Zobrazeno 1 - 10
of 112
pro vyhledávání: '"Shannon M Mumenthaler"'
Autor:
Yan Yang, Fang-Shu Ou, Emil Lou, Joanne Xiu, Hiroyuki Arai, Francesca Battaglin, Heinz-Josef Lenz, Richard M Goldberg, Anthony F Shields, Yasmine Baca, Philip A Philip, John L Marshall, W Michael Korn, Andreas Seeber, Natsuko Kawanishi, Jingyuan Wang, Shivani Soni, Wu Zhang, Shannon M Mumenthaler, Joshua Millstein, Priya Jayachandran, Federico Innocenti, Annika Lenz, Sandra Algaze, Taline Khoukaz, Evanthia Roussos Torres, Jim P Abraham, Benjamin A Weinberg, Alan P Venook
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 12, Iss 1 (2024)
Background The C-C motif chemokine receptor 5 (CCR5)/C-C motif chemokine ligand 5 (CCL5) axis plays a major role in colorectal cancer (CRC). We aimed to characterize the molecular features associated with CCR5/CCL5 expression in CRC and to determine
Externí odkaz:
https://doaj.org/article/0070d43d733f41d1a13e1ef74847bb8d
Autor:
Chiara Cremolini, Fotios Loupakis, Alfredo Falcone, Francesca Battaglin, Heinz-Josef Lenz, Natsuko Kawanishi, Shivani Soni, Wu Zhang, Christoph Mancao, Bodour Salhia, Shannon M Mumenthaler, Daniel J Weisenberger, Gangning Liang, Joshua Millstein
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 8, Iss 2 (2020)
Background Immunogenic cell death (ICD) is a tumor cell death involving both innate and adaptive immune responses. Given published findings that oxaliplatin, but not irinotecan, drives ICD, we investigated whether single nucleotide polymorphisms (SNP
Externí odkaz:
https://doaj.org/article/63cb3449cb6048b68ddf421f2efdf186
Autor:
Ahmadreza Ghaffarizadeh, Randy Heiland, Samuel H Friedman, Shannon M Mumenthaler, Paul Macklin
Publikováno v:
PLoS Computational Biology, Vol 14, Iss 2, p e1005991 (2018)
Many multicellular systems problems can only be understood by studying how cells move, grow, divide, interact, and die. Tissue-scale dynamics emerge from systems of many interacting cells as they respond to and influence their microenvironment. The i
Externí odkaz:
https://doaj.org/article/60c232cf9e84483a8a9fd61aac5cfed3
Publikováno v:
PLoS Computational Biology, Vol 12, Iss 8, p e1005077 (2016)
Experimental studies have shown that one key factor in driving the emergence of drug resistance in solid tumors is tumor hypoxia, which leads to the formation of localized environmental niches where drug-resistant cell populations can evolve and surv
Externí odkaz:
https://doaj.org/article/ef50b8c52ca3440e80a214f80408d638
Autor:
Hermann B Frieboes, Bryan R Smith, Zhihui Wang, Masakatsu Kotsuma, Ken Ito, Armin Day, Benjamin Cahill, Colin Flinders, Shannon M Mumenthaler, Parag Mallick, Eman Simbawa, A S Al-Fhaid, S R Mahmoud, Sanjiv S Gambhir, Vittorio Cristini
Publikováno v:
PLoS ONE, Vol 10, Iss 6, p e0129433 (2015)
We combine mathematical modeling with experiments in living mice to quantify the relative roles of intrinsic cellular vs. tissue-scale physiological contributors to chemotherapy drug resistance, which are difficult to understand solely through experi
Externí odkaz:
https://doaj.org/article/e3487eba4853460f845a086b6083a380
Autor:
Priya Jayachandran, Francesca Battaglin, Carly Strelez, Annika Lenz, Sandra Algaze, Shivani Soni, Jae Ho Lo, Yan Yang, Joshua Millstein, Wu Zhang, Jean C. Shih, Janice Lu, Shannon M. Mumenthaler, Darcy Spicer, Josh Neman, Evanthia T. Roussos Torres, Heinz-Josef Lenz
Publikováno v:
Oncogene. 42:627-637
Exploring the relationship between various neurotransmitters and breast cancer cell growth has revealed their likely centrality to improving breast cancer treatment. Neurotransmitters play a key role in breast cancer biology through their effects on
Publikováno v:
Trends in Biotechnology. 41:278-280
Autor:
Francesca Battaglin, Priya Jayachandran, Carly Strelez, Annika Lenz, Sandra Algaze, Shivani Soni, Jae Ho Lo, Yan Yang, Joshua Millstein, Wu Zhang, Evanthia T. Roussos Torres, Jean C. Shih, Shannon M. Mumenthaler, Josh Neman, Heinz-Josef Lenz
Publikováno v:
Oncogene. 41:4769-4778
The brain-gut axis, a bidirectional network between the central and enteric nervous system, plays a critical role in modulating the gastrointestinal tract function and homeostasis. Recently, increasing evidence suggests that neuronal signaling molecu
Autor:
Nikhil B. Ghate, Sungmin Kim, Yonghwan Shin, Jinman Kim, Michael Doche, Scott Valena, Alan Situ, Sangnam Kim, Suhn K. Rhie, Heinz-Josef Lenz, Tobias S. Ulmer, Shannon M. Mumenthaler, Woojin An
Publikováno v:
Nature Communications. 14
Our recent work has shown that DCAF1 (also known as VprBP) is overexpressed in colon cancer and phosphorylates histone H2AT120 to drive epigenetic gene inactivation and oncogenic transformation. We have extended these observations by investigating wh
Autor:
Anna M. Wu, James D. Marks, Yu Zhou, Parag Mallick, Shannon M. Mumenthaler, Kirstin A. Zettlitz, Richard Tavaré, Keyu Li
Supplementary methods not included in the primary manuscript.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b6d723b52a3859deb0f184d32429ccab
https://doi.org/10.1158/1535-7163.22502460
https://doi.org/10.1158/1535-7163.22502460