Zobrazeno 1 - 10
of 66
pro vyhledávání: '"Shannon M Matulis"'
Publikováno v:
PLoS ONE, Vol 7, Iss 12, p e52662 (2012)
Arsenic trioxide (ATO) has been tested in relapsed/refractory multiple myeloma with limited success. In order to better understand drug mechanism and resistance pathways in myeloma we generated an ATO-resistant cell line, 8226/S-ATOR05, with an IC50
Externí odkaz:
https://doaj.org/article/4fa433d622014801bf8364aec04ac7da
Autor:
Vikas A. Gupta, Shannon M. Matulis, Benjamin G. Barwick, R. Devin Bog, Conrad W. Shebelut, Mala Shanmugam, Paola Neri, Nizar J. Bahlis, Madhav V. Dhodapkar, Leonard T. Heffner, Craig C. Hofmeister, Nisha S. Joseph, Sagar Lonial, Jonathan L. Kaufman, David L. Jaye, Ajay K. Nooka, Lawrence H. Boise
Publikováno v:
Blood Cancer Journal, Vol 12, Iss 8, Pp 1-4 (2022)
Externí odkaz:
https://doaj.org/article/b80806186ba7462e812a4322e8cf5287
Autor:
Remya Nair, Vimal Subramaniam, Benjamin G. Barwick, Vikas A. Gupta, Shannon M. Matulis, Sagar Lonial, Lawrence H. Boise, Ajay K. Nooka, Kuzhali Muthumalaiappan, Mala Shanmugam
Publikováno v:
Haematologica, Vol 107, Iss 9 (2022)
Externí odkaz:
https://doaj.org/article/e555d024adbd48c9975863d16d1d2407
Autor:
Richa Bajpai, Aditi Sharma, Abhinav Achreja, Claudia L. Edgar, Changyong Wei, Arusha A. Siddiqa, Vikas A. Gupta, Shannon M. Matulis, Samuel K. McBrayer, Anjali Mittal, Manali Rupji, Benjamin G. Barwick, Sagar Lonial, Ajay K. Nooka, Lawrence H. Boise, Deepak Nagrath, Mala Shanmugam
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-16 (2020)
Venetoclax monotherapy is effective in 40% of t(11:14) positive multiple myeloma (MM). Here, the authors show that electron transport chain complex I (CI) and complex II (CII) activity predict MM sensitivity to venetoclax, and inhibition of CI with I
Externí odkaz:
https://doaj.org/article/ab542c51a366402d8b83cd98c687f243
Autor:
Shannon M. Matulis, Lawrence H. Boise
Publikováno v:
Haematologica, Vol 105, Iss 8 (2020)
Externí odkaz:
https://doaj.org/article/806d51b37060444ba0637fb53a57f83b
Autor:
Adriana E. Tron, Matthew A. Belmonte, Ammar Adam, Brian M. Aquila, Lawrence H. Boise, Elisabetta Chiarparin, Justin Cidado, Kevin J. Embrey, Eric Gangl, Francis D. Gibbons, Gareth P. Gregory, David Hargreaves, J. Adam Hendricks, Jeffrey W. Johannes, Ricky W. Johnstone, Steven L. Kazmirski, Jason G. Kettle, Michelle L. Lamb, Shannon M. Matulis, Ajay K. Nooka, Martin J. Packer, Bo Peng, Philip B. Rawlins, Daniel W. Robbins, Alwin G. Schuller, Nancy Su, Wenzhan Yang, Qing Ye, Xiaolan Zheng, J. Paul Secrist, Edwin A. Clark, David M. Wilson, Stephen E. Fawell, Alexander W. Hird
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-14 (2018)
High expression of Mcl-1 promotes tumorigenesis and resistance to anticancer therapies. Here they report a macrocyclic molecule with high selectivity and affinity for Mcl-1 that exhibits potent anti-tumor effects as single agent and in combination wi
Externí odkaz:
https://doaj.org/article/814ff3ef6b204d84917e2b025f3e1da9
Autor:
Lawrence H. Boise, Paula M. Vertino, Sagar Lonial, Jonathan J. Keats, Ajay K. Nooka, Craig C. Hofmeister, Yin C. Lin, Karen N. Conneely, David L. Jaye, Yanyan Gu, Doris R. Powell, Jonathan C. Patton, Shannon M. Matulis, Vikas A. Gupta, Benjamin G. Barwick
Purpose:Multiple myeloma is a malignancy of plasma cells. Extensive genetic and transcriptional characterization of myeloma has identified subtypes with prognostic and therapeutic implications. In contrast, relatively little is known about the myelom
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8231e1a1523111cfc9e76bccdc23f3ab
https://doi.org/10.1158/1078-0432.c.6530127
https://doi.org/10.1158/1078-0432.c.6530127
Autor:
Lawrence H. Boise, Paula M. Vertino, Sagar Lonial, Jonathan J. Keats, Ajay K. Nooka, Craig C. Hofmeister, Yin C. Lin, Karen N. Conneely, David L. Jaye, Yanyan Gu, Doris R. Powell, Jonathan C. Patton, Shannon M. Matulis, Vikas A. Gupta, Benjamin G. Barwick
Enrichment of transcription factor consensus binding motifs in regulatory elements predictive of gene expression associated with poor overall survival.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d2651b49bcdb0992053e0e2097624700
https://doi.org/10.1158/1078-0432.22479099
https://doi.org/10.1158/1078-0432.22479099
Autor:
Lawrence H. Boise, Paula M. Vertino, Sagar Lonial, Jonathan J. Keats, Ajay K. Nooka, Craig C. Hofmeister, Yin C. Lin, Karen N. Conneely, David L. Jaye, Yanyan Gu, Doris R. Powell, Jonathan C. Patton, Shannon M. Matulis, Vikas A. Gupta, Benjamin G. Barwick
Correlation of regulatory element transcription and gene expression in CoMMpass specimens.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::35d650b79c4a30ec3287aef7e564918d
https://doi.org/10.1158/1078-0432.22479105.v1
https://doi.org/10.1158/1078-0432.22479105.v1
Autor:
Lawrence H. Boise, Paula M. Vertino, Sagar Lonial, Jonathan J. Keats, Ajay K. Nooka, Craig C. Hofmeister, Yin C. Lin, Karen N. Conneely, David L. Jaye, Yanyan Gu, Doris R. Powell, Jonathan C. Patton, Shannon M. Matulis, Vikas A. Gupta, Benjamin G. Barwick
ATAC-seq data for Emory patients.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::50a73abc27baa80a64d4173c8b4e3cca
https://doi.org/10.1158/1078-0432.22479093
https://doi.org/10.1158/1078-0432.22479093