Zobrazeno 1 - 10
of 42
pro vyhledávání: '"Shannon M, Miller"'
Autor:
Viktoria Rungelrath, Mushtaq Ahmed, Linda Hicks, Shannon M. Miller, Kendal T. Ryter, Kyle Montgomery, George Ettenger, Alexander Riffey, Walid M. Abdelwahab, Shabaana Abdul Khader, Jay T. Evans
Publikováno v:
npj Vaccines, Vol 9, Iss 1, Pp 1-15 (2024)
Abstract Tuberculosis (TB), caused by Mycobacterium tuberculosis (Mtb), is one of the top infectious killers in the world. The only licensed vaccine against TB, Bacille Calmette-Guérin (BCG), provides variable protection against pulmonary TB, especi
Externí odkaz:
https://doaj.org/article/e64a5807aee049cf945f9fb7b0aaa82f
Autor:
Konner J. Jackson, Cassandra Buhl, Shannon M. Miller, Juhienah K. Khalaf, Janine Ward, Cherrokee Sands, Lois Walsh, Margaret Whitacre, David J. Burkhart, Hélène G. Bazin-Lee, Jay T. Evans
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
IntroductionAtopic diseases have been steadily increasing over the past decades and effective disease-modifying treatment options are urgently needed. These studies introduce a novel synthetic Toll-like receptor 4 (TLR4) agonist, INI-2004, with remar
Externí odkaz:
https://doaj.org/article/9b60a2eb358d47ecbea880c10933a65d
Autor:
Bethany Crouse, Shannon M. Miller, Peter Muelken, Linda Hicks, Jennifer R. Vigliaturo, Cheryl L. Marker, Alonso G. P. Guedes, Paul R. Pentel, Jay T. Evans, Mark G. LeSage, Marco Pravetoni
Publikováno v:
npj Vaccines, Vol 8, Iss 1, Pp 1-17 (2023)
Abstract Opioid use disorders (OUD) and overdose are public health threats worldwide. Widespread access to highly potent illicit synthetic opioids such as fentanyl is driving the recent rise in fatal overdoses. Vaccines containing fentanyl-based hapt
Externí odkaz:
https://doaj.org/article/84711b1689474c11879e5e0dec9e620c
Autor:
Shannon M. Miller, Bethany Crouse, Linda Hicks, Hardik Amin, Shelby Cole, Helene G. Bazin, David J. Burkhart, Marco Pravetoni, Jay T. Evans
Publikováno v:
npj Vaccines, Vol 8, Iss 1, Pp 1-14 (2023)
Abstract Opioid use disorders (OUD) and opioid-related fatal overdoses are a public health concern in the United States. Approximately 100,000 fatal opioid-related overdoses occurred annually from mid-2020 to the present, the majority of which involv
Externí odkaz:
https://doaj.org/article/1da1be1405e24b4a9876d785eb6244f4
Autor:
Valery C. Román-Cruz, Shannon M. Miller, Roman A. Schoener, Chase Lukasiewicz, Amelia K. Schmidt, Blair L. DeBuysscher, David Burkhart, Patrick R. Secor, Jay T. Evans
Publikováno v:
Vaccines, Vol 12, Iss 2, p 115 (2024)
Pseudomonas aeruginosa (Pa), a WHO priority 1 pathogen, resulted in approximately 559,000 deaths globally in 2019. Pa has a multitude of host-immune evasion strategies that enhance Pa virulence. Most clinical isolates of Pa are infected by a phage ca
Externí odkaz:
https://doaj.org/article/9528f8ec464343d482cb4702bfdba912
Autor:
Ana B. Enriquez, Angelo Izzo, Shannon M. Miller, Erica L. Stewart, Robert N. Mahon, Daniel J. Frank, Jay T. Evans, Jyothi Rengarajan, James A. Triccas
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Tuberculosis (TB) remains one of the leading causes of death worldwide due to a single infectious disease agent. BCG, the only licensed vaccine against TB, offers limited protection against pulmonary disease in children and adults. TB vaccine researc
Externí odkaz:
https://doaj.org/article/81e79ce3e4c342ac8953b5b791c71fc5
Autor:
Shannon M. Miller, Van Cybulski, Margaret Whitacre, Laura S. Bess, Mark T. Livesay, Lois Walsh, David Burkhart, Hélène G. Bazin, Jay T. Evans
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Most licensed seasonal influenza vaccines are non-adjuvanted and rely primarily on vaccine-induced antibody titers for protection. As such, seasonal antigenic drift and suboptimal vaccine strain selection often results in reduced vaccine efficacy. Fu
Externí odkaz:
https://doaj.org/article/f8c158556d2845698014a963a9729949
Autor:
Hye Kyung Lee, Michaela Willi, Shannon M. Miller, Sojung Kim, Chengyu Liu, David R. Liu, Lothar Hennighausen
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-6 (2018)
Understanding the risks of bystander and off-target editing is essential for genome engineering applications. Here, the authors analyze the fidelity of adenine and cytosine base editors in vivo.
Externí odkaz:
https://doaj.org/article/6f5a2eab54b647bf9d594d5cbd192da5
Autor:
Tony P. Huang, Zachary J. Heins, Shannon M. Miller, Brandon G. Wong, Pallavi A. Balivada, Tina Wang, Ahmad S. Khalil, David R. Liu
Publikováno v:
Nature Biotechnology. 41:96-107
Despite the availability of Cas9 variants with varied protospacer-adjacent motif (PAM) compatibilities, some genomic loci—especially those with pyrimidine-rich PAM sequences—remain inaccessible by high-activity Cas9 proteins. Moreover, broadening
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6b88cb5bc945d5b3c46f62083e22c96c
https://doi.org/10.1038/s41587-022-01410-2
https://doi.org/10.1038/s41587-022-01410-2
Autor:
Alyson J. Smith, Shannon M. Miller, Cassandra Buhl, Robert Child, Margaret Whitacre, Roman Schoener, George Ettenger, David Burkhart, Kendal Ryter, Jay T. Evans
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
Despite the ever present need for an effective Mycobacterium tuberculosis (Mtb) vaccine, efforts for development have been largely unsuccessful. Correlates of immune protection against Mtb are not wholly defined, but Th1 and likely Th17 adaptive immu
Externí odkaz:
https://doaj.org/article/be15d9495c834bfea241ccae8fbb3636