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pro vyhledávání: '"Shannon L. Thol"'
Kinetic Stability of Long-Lived Human Lens γ-Crystallins and Their Isolated Double Greek Key Domains
Autor:
Ishara A. Mills-Henry, Eugene Serebryany, Jonathan King, Shannon L. Thol, Melissa S. Kosinski-Collins
Publikováno v:
Biophys J
The γ-crystallins of the eye lens nucleus are among the longest-lived proteins in the human body. Synthesized in utero, they must remain folded and soluble throughout adulthood to maintain lens transparency and avoid cataracts. γD- and γS-crystall
Autor:
Eugene Serebryany, Shannon L. Thol, Jonathan King, Ishara Mills Henry, Melissa S. Kosinski-Collins
Publikováno v:
Biophysical Journal. 118:181a
Autor:
Shannon L. Thol, Melissa S. Kosinski-Collins, Eugene Serebryany, Jonathan King, Ishara Mills Henry
Publikováno v:
Biophysical Journal. 116:321a-322a
Autor:
Katerina, Papanikolopoulou, Ishara, Mills-Henry, Shannon L, Thol, Yongting, Wang, Abby A R, Gross, Daniel A, Kirschner, Sean M, Decatur, Jonathan, King
Publikováno v:
Molecular Vision
Amyloid fibrils are associated with a variety of human protein misfolding and protein deposition diseases. Previous studies have shown that bovine crystallins form amyloid fibers under denaturing conditions and amyloid fibers accumulate in the lens o