Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Shannon L. Planer"'
Autor:
Emily Ainslie, Colette M. Hughes, Alan Aderem, Louis J. Picker, Scott G. Hansen, Thomas G. Evans, Michele Stone, Shannon L. Planer, Abigail B. Ventura, Daniel Malouli, Smitha Shankar, Guangwu Xu, Daniel E. Zak, Aurelio Bonavia, Roxanne M. Gilbride, Parker Rundstrom, Alfred W. Legasse, Lynn M. Amon, Christina Armstrong, Lauren Herlache, Kurt T. Randall, Robert C. Zweig, Martin Messerle, Dominick Laddy, John M. Turner, Klaus Früh, Haesun Park, Michael A. Jarvis, Emily E. Marshall, Andrea N. Selseth, Miranda Fischer, Joseph Valvo, Jackie Braun, Andrew W. Sylwester, Galit Alter, Michael K. Axthelm, Julia C. Ford, Lenette L. Lu, Paul T. Edlefsen, Matthew S. Lewis
Publikováno v:
Nature Medicine. 24:130-143
Despite widespread use of the bacille Calmette-Guerin (BCG) vaccine, tuberculosis (TB) remains a leading cause of global mortality from a single infectious agent (Mycobacterium tuberculosis or Mtb). Here, over two independent Mtb challenge studies, w
Autor:
Eileen D. Villasante, Kimberly A. Edgel, Joao C. Aguiar, Louis J. Picker, John M. Turner, Thomas L. Richie, Jennie Womack, Al Legasse, Paul T. Edlefsen, Isabel Scholz, Andrea Renner, Julia C. Ford, Klaus Früh, Walter R. Weiss, Michael K. Axthelm, Shannon L. Planer, Guangwu Xu, Mikayla Grey, Brandyce St. Laurent, Scott G. Hansen
Publikováno v:
PLoS ONE, Vol 14, Iss 1, p e0210252 (2019)
PLoS ONE
PLoS ONE
The development of a sterilizing vaccine against malaria remains one of the highest priorities for global health research. While sporozoite vaccines targeting the pre-erythrocytic stage show great promise, it has not been possible to maintain efficac
Autor:
Scott W. Wong, Alfred W. Legasse, Michael K. Axthelm, Shannon L. Planer, Anne D. Lewis, Minsha Manoharan, Jeremy P. Huynh, Margo A. Brinton, Stephanie Rawlings, Eric F. Donaldson, Ralph S. Baric, Mary F. Dickerson, Jerilyn K. Pecotte, Lois M. A. Colgin, Heather A. Vatter
Publikováno v:
Virology
Simian hemorrhagic fever virus is an arterivirus that naturally infects species of African nonhuman primates causing acute or persistent asymptomatic infections. Although it was previously estimated that 1% of baboons are SHFV-positive, more than 10%
Autor:
Shannon L. Planer, Katherine B. Hammond, Benjamin J. Burwitz, Jonah B. Sacha, Merete A. Ohme, Adam J. Ericsen, Yoram Richter, Alfred W. Legasse, Gershon Golomb, Jason S. Reed
Publikováno v:
Journal of Leukocyte Biology
Nonhuman primates are critical animal models for the study of human disorders and disease and offer a platform to assess the role of immune cells in pathogenesis via depletion of specific cellular subsets. However, this model is currently hindered by
Autor:
Shannon L. Planer, Magdalene So, Nyiawung A. Taku, Nathan J. Weyand, Susan Clary, Lewis M. Brown, Theodore R. Hobbs, Anne M. Wertheimer, Alfred W. Legasse, Scott W. Wong, Nicolas Biais, Dustin L. Higashi, Lindsay D. Gregston, Jennifer L. Sisko, Michael K. Axthelm
Publikováno v:
Proceedings of the National Academy of Sciences. 110:3059-3064
The strict tropism of many pathogens for man hampers the development of animal models that recapitulate important microbe–host interactions. We developed a rhesus macaque model for studying Neisseria –host interactions using Neisseria species ind
Autor:
Andrew W. Sylwester, Mukta Rohankhedkar, Chike O. Abana, Byung Park, Afam A. Okoye, Richard Lum, Christopher Pexton, Matthew D. Reyes, Alfred W. Legasse, Michael Piatak, Louis J. Picker, Shannon L. Planer, Audrie Pattenn, Michael K. Axthelm, Jeffrey D. Lifson
Publikováno v:
The Journal of Experimental Medicine
Memory CD4+ T cell homeostasis and AIDS progression are independent of naive CD4+ T cells in SIV infection of nonhuman primates.
The development of AIDS in chronic HIV/simian immunodeficiency virus (SIV) infection has been closely linked to prog
The development of AIDS in chronic HIV/simian immunodeficiency virus (SIV) infection has been closely linked to prog
Autor:
Shannon L. Planer, Alfred W. Legasse, Guangwu Xu, Paul T. Edlefsen, Abigail B. Ventura, Jay A. Nelson, Kelli Oswald, Jacob D. Estes, Yuan Li, Awbrey N. Gilliam, Jonah B. Sacha, Benjamin J. Burwitz, Brandon F. Keele, Michael K. Axthelm, Julia C. Ford, Jeffrey D. Lifson, Michael Piatak, Matthew S. Lewis, John M. Turner, Colette M. Hughes, Rebecca Shoemaker, Nathan Whizin, Klaus Früh, Scott G. Hansen, Louis J. Picker, Roxanne M. Gilbride
Publikováno v:
Nature. 547:123-124
Autor:
Michael K. Axthelm, Helen Li, Scott W. Wong, Alfred W. Legasse, Michael F. Powers, Ilhem Messaoudi, Shannon L. Planer, Flora Engelmann, Minsha Manoharan, Beata U. Orzechowska, Bonnie Yen, Bridget A. Robinson, John M. Jones, Jerald Sprague, Alexander Barron, Megan A. O'Connor, Jennifer Wilk, Ryan D. Estep
Publikováno v:
Journal of Virology. 85:9527-9542
Monkeypox virus (MPXV) is an orthopoxvirus closely related to variola virus, the causative agent of smallpox. Human MPXV infection results in a disease that is similar to smallpox and can also be fatal. Two clades of MPXV have been identified, with v
Autor:
Mukta Rohankhedkar, Lia Coyne-Johnson, Louis J. Picker, Joshua M. Walker, Richard Lum, Haesun Park, Andrew W. Sylwester, Alfred W. Legasse, Joern E. Schmitz, Michael K. Axthelm, Donald L. Sodora, Michael Piatak, Shannon L. Planer, Francois Villinger, Jeffrey D. Lifson, Afam A. Okoye
Publikováno v:
The Journal of Experimental Medicine
Depletion of CD8(+) lymphocytes during acute simian immunodeficiency virus (SIV) infection of rhesus macaques (RMs) results in irreversible prolongation of peak-level viral replication and rapid disease progression, consistent with a major role for C
Autor:
Jason M. Brenchley, Jeffrey D. Lifson, Donald L. Sodora, Alfred W. Legasse, Martin Meier-Schellersheim, Afam A. Okoye, John B. Edgar, Michael Piatak, Shoko I. Hagen, Vernon C. Maino, Michael K. Axthelm, Shannon L. Planer, Joshua M. Walker, Richard Lum, Mukta Rohankhedkar, Louis J. Picker, Andrew W. Sylwester, Zvi Grossman, Daniel C. Douek
Publikováno v:
The Journal of Experimental Medicine
Primary simian immunodeficiency virus (SIV) infections of rhesus macaques result in the dramatic depletion of CD4(+) CCR5(+) effector-memory T (T(EM)) cells from extra-lymphoid effector sites, but in most infections, an increased rate of CD4(+) memor