Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Shannon L. Grahek"'
Autor:
Nicole Maier, Shannon L. Grahek, Jane Halpern, Suzanne Restrepo, Felipe Troncoso, Janet Shimko, Olga Torres, Jaime Belkind-Gerson, David A. Sack, Ann-Mari Svennerholm, Björn Gustafsson, Björn Sjöstrand, Nils Carlin, A. Louis Bourgeois, Chad K. Porter
Publikováno v:
Microorganisms, Vol 11, Iss 10, p 2414 (2023)
The efficacy of an Oral Whole Cell ETEC Vaccine (OEV) against Travelers’ Diarrhea (TD) was reexamined using novel outcome and immunologic measures. More specifically, a recently developed disease severity score and alternative clinical endpoints we
Externí odkaz:
https://doaj.org/article/369c3920388d46768fce8147e5741cf4
Autor:
Chad K. Porter, David R. Tribble, Barbara DeNearing, Stephen J. Savarino, Robin McKenzie, Shannon L. Grahek, Aisling O'Dowd, Stephanie A. Sincock, Carl Brinkley, Steven T. Poole, Joseph H. Crabb, Colleen M. Woods, A. Louis Bourgeois, Hye Kim
Publikováno v:
The Journal of Infectious Diseases. 220:505-513
BackgroundEnterotoxigenic Escherichia coli (ETEC) commonly cause diarrhea in children living in developing countries and in travelers to those regions. ETEC are characterized by colonization factors (CFs) that mediate intestinal adherence. We assesse
Autor:
Dang Duc Anh, Anna Lena Lopez, Vu Dinh Thiem, Shannon L Grahek, Tran Nhu Duong, Jin Kyung Park, Hye Jung Kwon, Michael Favorov, Nguyen Tran Hien, John D Clemens
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 5, Iss 1, p e1006 (2011)
BACKGROUND: Killed oral cholera vaccines (OCVs) are available but not used routinely for cholera control except in Vietnam, which produces its own vaccine. In 2007-2008, unprecedented cholera outbreaks occurred in the capital, Hanoi, prompting immuni
Externí odkaz:
https://doaj.org/article/cea54587506c4f178fb68de91a1b137d
Autor:
Chad K. Porter, Stephanie A. Sincock, Stephen J. Savarino, Joseph H. Crabb, Shannon L. Grahek, Colleen M. Woods, Joyce A. Cantrell, David R. Tribble, Robin McKenzie, A. Louis Bourgeois, Aisling O'Dowd, Carl Brinkley, Barbara DeNearing, Hye Kim, Steven T. Poole
Publikováno v:
The Journal of Infectious Diseases. 216:7-13
Background Tip-localized adhesive proteins of bacterial fimbriae from diverse pathogens confer protection in animal models, but efficacy in humans has not been reported. Enterotoxigenic Escherichia coli (ETEC) commonly elaborate colonization factors
Autor:
Robin McKenzie, Thomas L. Hale, Malabi M. Venkatesan, Colleen C. Woods, Andrea Feller, Dilara Islam, David N. Taylor, Shannon L. Grahek, August L. Bourgeois
Publikováno v:
Vaccine. 29:8487-8489
Accurately assessing mucosal immune responses to candidate vaccines remains a technical challenge. ELISPOT is widely used as a surrogate of mucosal immune response by directly enumerating circulating antibody secreting cells (ASCs), while antibody in
Autor:
Stephanie A. Sincock, David R. Tribble, Chad K. Porter, A. Louis Bourgeois, Joyce A. Cantrell, Colleen M. Woods, Robin McKenzie, Peter J. Sebeny, Barbara DeNearing, Shannon L. Grahek, David A. Sack, Aisling O'Dowd, Stephen J. Savarino
Publikováno v:
The Journal of infectious diseases. 204(1)
Human challenges with enterotoxigenic Escherichia coli (ETEC) have broadened our understanding of this important enteropathogen. We report findings from the first challenge studies using ETEC-expressing colonization factor fimbria CS17 and CS19. LSN0
Autor:
Robin McKenzie, Thomas L. Hale, Shannon L. Grahek, Andrea M. Jones, Arlene Bloom, Malabi M. Venkatesan, Marcia K. Wolf, David N. Taylor, A. Louis Bourgeois, Dilara Islam
Publikováno v:
Vaccine. 26(26)
Among Shigella serotypes Shigella dysenteriae type 1 produces the most severe disease, including cases of hemolytic-uremic syndrome and pandemic outbreaks. WRSd1 is a live S. dysenteriae 1 strain attenuated by deletion of the virG(icsA) gene, which e