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Autor:
Daryl M. Okamura, Allison A. Eddy, Ravi Maruvada, Sarah J. Collins, Streamson C. Chua, Jesus M. Lopez-Guisa, Guoqiang Zhang, Shannon L. Alexander, Xiaohe Cai, Shunya Matsuo
Publikováno v:
Nephron Experimental Nephrology. 104:e23-e34
Background:Elevated plasma levels of plasminogen activator inhibitor-1 (PAI-1) are observed in patients with obesity, hypertension and diabetes, and several observations suggest that PAI-1 mediates diabetic vascular complications. Although increased