Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Shannon L Kordus"'
Autor:
Kateryna Nabukhotna, Shannon L Kordus, John A Shupe, Rubén Cano Rodríguez, Anna Smith, Julia K Bohannon, M Kay Washington, D Borden Lacy
Publikováno v:
PLoS Pathogens, Vol 20, Iss 9, p e1012568 (2024)
Clostridioides difficile is a spore-forming pathogen and the most common cause of healthcare-associated diarrhea and colitis in the United States. Besides producing the main virulence factors, toxin A (TcdA) and toxin B (TcdB), many of the common cli
Externí odkaz:
https://doaj.org/article/e4b4bb5a738b4efeab523e61d2c2ba67
Autor:
Shannon L Kordus, Heather K Kroh, Rubén Cano Rodríguez, Rebecca A Shrem, F Christopher Peritore-Galve, John A Shupe, Brian E Wadzinski, D Borden Lacy, Benjamin W Spiller
Publikováno v:
PLoS Pathogens, Vol 19, Iss 10, p e1011496 (2023)
Clostridioides difficile is a leading cause of antibiotic-associated diarrhea and nosocomial infection in the United States. The symptoms of C. difficile infection (CDI) are associated with the production of two homologous protein toxins, TcdA and Tc
Externí odkaz:
https://doaj.org/article/5c0a09492fa445118a189e4830bc1d37
Autor:
Yusuke Minato, Surendra Dawadi, Shannon L. Kordus, Abiram Sivanandam, Courtney C. Aldrich, Anthony D. Baughn
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-7 (2018)
The antibiotics trimethoprim (TMP) and sulfamethoxazole (SMX) synergistically inhibit bacterial tetrahydrofolate biosynthesis, apparently because SMX potentiates TMP activity. Here, Minato et al. identify a metabolic feedback loop in this pathway, re
Externí odkaz:
https://doaj.org/article/693c54c67db3481ba3a9bc7c7cdf3759
Autor:
Michael D. Howe, Shannon L. Kordus, Malcolm S. Cole, Allison A. Bauman, Courtney C. Aldrich, Anthony D. Baughn, Yusuke Minato
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 8 (2018)
para-Aminosalicylic acid (PAS) is a second-line anti-tubercular drug that is used for the treatment of drug-resistant tuberculosis (TB). PAS efficacy in the treatment of TB is limited by its lower potency against Mycobacterium tuberculosis relative t
Externí odkaz:
https://doaj.org/article/4245dd97c2cc47328c586d12bec19087
Publikováno v:
Nat Rev Microbiol
Clostridioides difficile is a Gram-positive anaerobe that can cause a spectrum of disorders that range in severity from mild diarrhoea to fulminant colitis and/or death. The bacterium produces up to three toxins, which are considered the major virule
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fd8832f58ba63a748c5f477ffff36540
https://doi.org/10.1038/s41579-021-00660-2
https://doi.org/10.1038/s41579-021-00660-2