Zobrazeno 1 - 10
of 448
pro vyhledávání: '"Shannon Glaser"'
Autor:
Konstantina Kyritsi, Nan Wu, Tianhao Zhou, Guido Carpino, Leonardo Baiocchi, Lindsey Kennedy, Lixian Chen, Ludovica Ceci, Alison Ann Meyer, Nipuni Barupala, Antonio Franchitto, Paolo Onori, Burcin Ekser, Eugenio Gaudio, Chaodong Wu, Corinn Marakovits, Sanjukta Chakraborty, Heather Francis, Shannon Glaser, Gianfranco Alpini
Publikováno v:
Cell & Bioscience, Vol 13, Iss 1, Pp 1-22 (2023)
Abstract Background Alcohol-related liver disease (ALD) is characterized by ductular reaction (DR), liver inflammation, steatosis, fibrosis, and cirrhosis. The secretin (Sct)/secretin receptor (SR) axis (expressed only by cholangiocytes) regulates li
Externí odkaz:
https://doaj.org/article/66bae7ada46a4c41b1ce528643d8098f
Autor:
Tianhao Zhou, Vik Meadows, Debjyoti Kundu, Konstantina Kyritsi, Travis Owen, Ludovica Ceci, Guido Carpino, Paolo Onori, Eugenio Gaudio, Nan Wu, Shannon Glaser, Burcin Ekser, Gianfranco Alpini, Lindsey Kennedy, Heather Francis
Publikováno v:
Hepatology Communications, Vol 6, Iss 10, Pp 2715-2731 (2022)
Abstract Bile ducts are heterogenous in structure and function, and primary sclerosing cholangitis (PSC) damages specific bile ducts leading to ductular reaction (DR), mast cell (MC) infiltration, increased histamine release, inflammation, and fibros
Externí odkaz:
https://doaj.org/article/e83b2d915a0a497a8aaef3f28af65ce5
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 15, Iss 3, Pp 803-805 (2023)
Externí odkaz:
https://doaj.org/article/fc71f3ea5deb45d8853b9ff911aa602d
Autor:
April O’Brien, Tianhao Zhou, Tori White, Abigail Medford, Lixian Chen, Konstantina Kyritsi, Nan Wu, Jonathan Childs, Danaleigh Stiles, Ludovica Ceci, Sanjukta Chakraborty, Burcin Ekser, Leonardo Baiocchi, Guido Carpino, Eugenio Gaudio, Chaodong Wu, Lindsey Kennedy, Heather Francis, Gianfranco Alpini, Shannon Glaser
Publikováno v:
Hepatology Communications, Vol 6, Iss 7, Pp 1574-1588 (2022)
Fibroblast growth factor 1 (FGF1) belongs to a family of growth factors involved in cellular growth and division. MicroRNA 16 (miR‐16) is a regulator of gene expression, which is dysregulated during liver injury and insult. However, the role of FGF
Externí odkaz:
https://doaj.org/article/69304a63d3f14d1cb6f65abe81d68eed
Autor:
Zahra Alghoul, Junsik Sung, Kenji Wu, Gianfranco Alpini, Shannon Glaser, Chunhua Yang, Didier Merlin
Publikováno v:
Bio-Protocol, Vol 13, Iss 7 (2023)
Interleukin-22 (IL-22) has been demonstrated as a critical regulator of epithelial homeostasis and repair; it showed an anti-inflammatory effect against ulcerative colitis. Local microinjection of IL-22 cDNA vector has been shown to be effective in t
Externí odkaz:
https://doaj.org/article/e27e20b27f4a4c9a9370ddf0066cd2a2
Autor:
Diletta Overi, Guido Carpino, Laura Cristoferi, Paolo Onori, Lindsey Kennedy, Heather Francis, Nicola Zucchini, Cristina Rigamonti, Mauro Viganò, Annarosa Floreani, Daphne D’Amato, Alessio Gerussi, Rosanna Venere, Gianfranco Alpini, Shannon Glaser, Domenico Alvaro, Pietro Invernizzi, Eugenio Gaudio, Vincenzo Cardinale, Marco Carbone
Publikováno v:
JHEP Reports, Vol 4, Iss 11, Pp 100556- (2022)
Background & Aims: Primary biliary cholangitis (PBC) is a chronic cholangiopathy characterised by immuno-mediated injury of interlobular bile ducts leading to intrahepatic cholestasis and progressive liver fibrosis. PBC histology is characterised by
Externí odkaz:
https://doaj.org/article/d0606557065e42109cd7f0e8e0b8838f
Autor:
Leonardo Baiocchi, Shannon Glaser, Heather Francis, Lindsey Kennedy, Eric Felli, Gianfranco Alpini, Jordi Gracia‐Sancho
Publikováno v:
Hepatology Communications, Vol 5, Iss 7, Pp 1125-1137 (2021)
The aging process is represented by the time‐dependent decay in physiologic functions of living beings. Major interest has been focused in recent years on the determinants of this progressive condition due to its correlative relationship with the o
Externí odkaz:
https://doaj.org/article/4c60cca8127f4f58a8a298be84acc229
Autor:
Xin Guo, Bilian Zhu, Hang Xu, Honggui Li, Boxiong Jiang, Yina Wang, Benrong Zheng, Shannon Glaser, Gianfranco Alpini, Chaodong Wu
Publikováno v:
Liver Research, Vol 4, Iss 3, Pp 136-144 (2020)
Background and objectives: Hepatic steatosis and inflammation are key characteristics of non-alcoholic fatty liver disease (NAFLD). However, whether and how hepatic steatosis and liver inflammation are differentially regulated remains to be elucidate
Externí odkaz:
https://doaj.org/article/93f7eedd3f7c4c2faf624ad44c2579a5
Autor:
Priyanka Banerjee, Subhashree Kumaravel, Sukanya Roy, Niyanshi Gaddam, Johnny Odeh, Kayla J. Bayless, Shannon Glaser, Sanjukta Chakraborty
Publikováno v:
Cells, Vol 12, Iss 4, p 526 (2023)
Conjugated bile acids (BA) are significantly elevated in several liver pathologies and in the metastatic lymph node (LN). However, the effects of BAs on pathological lymphangiogenesis remains unknown. The current study explores the effects of BAs on
Externí odkaz:
https://doaj.org/article/7108d2a56f2e4e4aa56e71bdceebe2cf
Autor:
Vik Meadows, Leonardo Baiocchi, Debjyoti Kundu, Keisaku Sato, Yessenia Fuentes, Chaodong Wu, Sanjukta Chakraborty, Shannon Glaser, Gianfranco Alpini, Lindsey Kennedy, Heather Francis
Publikováno v:
Frontiers in Molecular Biosciences, Vol 8 (2021)
Cellular senescence is a pathophysiological phenomenon in which proliferative cells enter cell cycle arrest following DNA damage and other stress signals. Natural, permanent DNA damage can occur after repetitive cell division; however, acute stress o
Externí odkaz:
https://doaj.org/article/5ff3901a9c2a4102a124718c2466f0be