Candida-induced granulocytic myeloid-derived suppressor cells are protective against polymicrobial sepsis

Autor: Shannon Esher Righi, Amanda J. Harriett, Elizabeth A. Lilly, Paul L. Fidel, Mairi C. Noverr

Publikováno v: mBio, Vol 14, Iss 5 (2023)

ABSTRACT Polymicrobial intra-abdominal infections (IAI) can lead to life-threatening sepsis with significant morbidity and mortality, especially when pathogenic fungi are involved. We have employed an established clinically relevant mouse model of fu

Externí odkaz: https://doaj.org/article/578699ebd6e44690bb0e88d032773236

Gender disparities among medical students choosing to pursue careers in medical research: a secondary cross-sectional cohort analysis

Autor: Austin Snyder, David Xiang, Alison Smith, Shannon Esswein, Omar Toubat, John Di Capua, Jennifer M. Kwan, Dania Daye

Publikováno v: BMC Medical Education, Vol 21, Iss 1, Pp 1-10 (2021)

Abstract Background Though the proportion of women in medical schools has increased, gender disparities among those who pursue research careers still exists. In this study, we seek to better understand the main factors contributing to the existing ge

Externí odkaz: https://doaj.org/article/fcfeef3462164f4cb5c3f6e304d6ed36

Efficacy of Candida dubliniensis and Fungal β-Glucans in Inducing Trained Innate Immune Protection Against Inducers of Sepsis

Autor: Amanda J. Harriett, Shannon Esher Righi, Elizabeth A. Lilly, Paul Fidel, Mairi C. Noverr

Publikováno v: Frontiers in Cellular and Infection Microbiology, Vol 12 (2022)

Fungal-bacterial intra-abdominal infections (IAI) can lead to sepsis with significant morbidity and mortality. We have established a murine model of Candida albicans (Ca) and Staphylococcus aureus (Sa) IAI that results in acute lethal sepsis. Prior i

Externí odkaz: https://doaj.org/article/5f4fea64c6cf4a07a613e97e8f94448f

Comparative analysis of RNA enrichment methods for preparation of Cryptococcus neoformans RNA sequencing libraries

Autor: Calla L Telzrow, Paul J Zwack, Shannon Esher Righi, Fred S Dietrich, Cliburn Chan, Kouros Owzar, J Andrew Alspaugh, Joshua A Granek

Publikováno v: G3: Genes, Genomes, Genetics, Vol 11, Iss 11 (2021)

AbstractRNA sequencing (RNA-Seq) experiments focused on gene expression involve removal of ribosomal RNA (rRNA) because it is the major RNA constituent of cells. This process, called RNA enrichment, is done primarily to reduce cost: without rRNA remo

Externí odkaz: https://doaj.org/article/1f1e7f4c0f8d42818c119b3b8b401db4

The effect of sodium bicarbonate mini-tablets ingested in a carbohydrate hydrogel system on 40 km cycling time trial performance and metabolism in trained male cyclists.

Autor: Shannon ES; Nutrition, Sport and Exercise Performance Research Group, Department of Sport and Physical Activity, Edge Hill University, Ormskirk, UK. elishannon48@gmail.com., Regnier A; Nutrition, Sport and Exercise Performance Research Group, Department of Sport and Physical Activity, Edge Hill University, Ormskirk, UK., Dobson B; Nutrition, Sport and Exercise Performance Research Group, Department of Sport and Physical Activity, Edge Hill University, Ormskirk, UK., Yang X; China Institute of Sport and Health Science, Beijing Sport University, Beijing, China., Sparks SA; Maurten AB, Gothenburg, Sweden.; Research Institute for Sport and Exercise Sciences, Liverpool John Moores University, Liverpool, UK., Mc Naughton LR; Nutrition, Sport and Exercise Performance Research Group, Department of Sport and Physical Activity, Edge Hill University, Ormskirk, UK.

Publikováno v: European journal of applied physiology [Eur J Appl Physiol] 2024 Dec; Vol. 124 (12), pp. 3671-3682. Date of Electronic Publication: 2024 Jul 28.