Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Shannon E. Best"'
Autor:
Rajiv Kumar, Patrick T. Bunn, Siddharth Sankar Singh, Susanna S. Ng, Marcela Montes de Oca, Fabian De Labastida Rivera, Shashi Bhushan Chauhan, Neetu Singh, Rebecca J. Faleiro, Chelsea L. Edwards, Teija C.M. Frame, Meru Sheel, Rebecca J. Austin, Steven W. Lane, Tobias Bald, Mark J. Smyth, Geoffrey.R. Hill, Shannon E. Best, Ashraful Haque, Dillon Corvino, Nic Waddell, Lambross Koufariotis, Pamela Mukhopadhay, Madhukar Rai, Jaya Chakravarty, Om Prakash Singh, David Sacks, Susanne Nylen, Jude Uzonna, Shyam Sundar, Christian R. Engwerda
Publikováno v:
Cell Reports, Vol 30, Iss 8, Pp 2512-2525.e9 (2020)
Summary: Type I interferons (IFNs) play critical roles in anti-viral and anti-tumor immunity. However, they also suppress protective immune responses in some infectious diseases. Here, we identify type I IFNs as major upstream regulators of CD4+ T ce
Externí odkaz:
https://doaj.org/article/e785a439bde64e73885e903f52fe0682
Autor:
Marcela Montes de Oca, Rajiv Kumar, Fabian de Labastida Rivera, Fiona H. Amante, Meru Sheel, Rebecca J. Faleiro, Patrick T. Bunn, Shannon E. Best, Lynette Beattie, Susanna S. Ng, Chelsea L. Edwards, Glen M. Boyle, Ric N. Price, Nicholas M. Anstey, Jessica R. Loughland, Julie Burel, Denise L. Doolan, Ashraful Haque, James S. McCarthy, Christian R. Engwerda
Publikováno v:
Cell Reports, Vol 17, Iss 2, Pp 399-412 (2016)
The development of immunoregulatory networks is important to prevent disease. However, these same networks allow pathogens to persist and reduce vaccine efficacy. Here, we identify type I interferons (IFNs) as important regulators in developing anti-
Externí odkaz:
https://doaj.org/article/9b05fd1ed67d459e9852bf440f0c5250
Autor:
Ashraful Haque, Shannon E. Best, Dillon Corvino, Fabian de Labastida Rivera, Rajiv Kumar, Marcela Montes de Oca, David B. Sacks, Meru Sheel, Chelsea L. Edwards, Pamela Mukhopadhay, Rebecca Austin, Teija C. M. Frame, Neetu Singh, Madhukar Rai, Patrick T. Bunn, Siddharth Sankar Singh, Susanna S. Ng, Geoffrey R. Hill, Rebecca J. Faleiro, Steven W. Lane, Nic Waddell, Om Prakash Singh, Shyam Sundar, Jude E. Uzonna, Mark J. Smyth, Shashi Bhushan Chauhan, Tobias Bald, Susanne Nylén, Christian R. Engwerda, Lambross Koufariotis, Jaya Chakravarty
Publikováno v:
Cell Reports, Vol 30, Iss 8, Pp 2512-2525.e9 (2020)
Cell reports
Cell reports
SUMMARY Type I interferons (IFNs) play critical roles in anti-viral and anti-tumor immunity. However, they also suppress protective immune responses in some infectious diseases. Here, we identify type I IFNs as major upstream regulators of CD4+ T cel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::78bf3ffbda169ab00612b40ec142a440
http://www.sciencedirect.com/science/article/pii/S2211124720301339
http://www.sciencedirect.com/science/article/pii/S2211124720301339
Autor:
Christian R. Engwerda, Arya Sheela Nair, Rebecca Austin, Shannon E. Best, Daniel Fernandez-Ruiz, Lianne I. M. Lansink, Ashraful Haque, Gayle M. Davey, Megan S. F. Soon, Chelsea L. Edwards, William R. Heath, Kate Schroder, Lily Fogg, Geoffrey R. Hill, Steven W. Lane, Jane A. C. Wilson, Ismail Sebina, Urijah N. Liligeto, Andreas Suhrbier, Kylie R. James
Publikováno v:
The Journal of Immunology. 200:1443-1456
Differentiation of CD4+ Th cells is critical for immunity to malaria. Several innate immune signaling pathways have been implicated in the detection of blood-stage Plasmodium parasites, yet their influence over Th cell immunity remains unclear. In th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3060e008910708daddfbafcb568b6b17
https://doi.org/10.4049/jimmunol.1700782
https://doi.org/10.4049/jimmunol.1700782
Autor:
Trish Elliott, Rosemary A. Aogo, Jasmin Akter, Ashraful Haque, Jessica A. Engel, Shannon E. Best, David S. Khoury, Deborah Cromer, Miles P. Davenport, Bryce S. Thomas, Kylie R. James, Ismail Sebina, Megan S. F. Soon, Kate H. Gartlan
Publikováno v:
International Journal for Parasitology. 47:913-922
The artemisinins are the first-line therapy for severe and uncomplicated malaria, since they cause rapid declines in parasitemia after treatment. Despite this, in vivo mechanisms underlying this rapid decline remain poorly characterised. The overall
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::61660a70a0099d018c0aa7e9e1341cd4
https://doi.org/10.1016/j.ijpara.2017.05.009
https://doi.org/10.1016/j.ijpara.2017.05.009
Autor:
Ashraful Haque, Shannon E Best, Fiona H Amante, Seri Mustafah, Laure Desbarrieres, Fabian de Labastida, Tim Sparwasser, Geoffrey R Hill, Christian R Engwerda
Publikováno v:
PLoS Pathogens, Vol 6, Iss 12, p e1001221 (2010)
Studies in malaria patients indicate that higher frequencies of peripheral blood CD4(+) Foxp3(+) CD25(+) regulatory T (Treg) cells correlate with increased blood parasitemia. This observation implies that Treg cells impair pathogen clearance and thus
Externí odkaz:
https://doaj.org/article/0bc03bb710e84f59aad5adc95adbcf44
Autor:
Rebecca J. Faleiro, Ric N. Price, Nicholas M. Anstey, Christian R. Engwerda, Marcela Montes de Oca, Susanna S. Ng, Meru Sheel, Julie G. Burel, Rajiv Kumar, Chelsea L. Edwards, Shannon E. Best, Patrick T. Bunn, Glen M. Boyle, Jessica R. Loughland, Ashraful Haque, Fabian de Labastida Rivera, James S. McCarthy, Fiona H. Amante, Lynette Beattie, Denise L. Doolan
Publikováno v:
Cell Reports, Vol 17, Iss 2, Pp 399-412 (2016)
Cell reports
Cell reports
Summary The development of immunoregulatory networks is important to prevent disease. However, these same networks allow pathogens to persist and reduce vaccine efficacy. Here, we identify type I interferons (IFNs) as important regulators in developi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7f99776f17dfd7ca0b6cbf88d5b3438c
http://www.sciencedirect.com/science/article/pii/S2211124716312207
http://www.sciencedirect.com/science/article/pii/S2211124716312207
Autor:
Christian R. Engwerda, Shaun R. McColl, Ashraful Haque, Rachel D. Kuns, Patrick T. Bunn, Marcela Montes de Oca, Antiopi Varelias, Fabian de Labastida Rivera, Meru Sheel, Fiona H. Amante, Kelli P. A. MacDonald, Rebecca J. Faleiro, Geoff R. Hill, Mark J. Smyth, Lynette Beattie, Shannon E. Best, Rajiv Kumar, Chelsea L. Edwards, Teija C. M. Frame, Susanna S. Ng
Publikováno v:
The Journal of Immunology. 195:5707-5717
Intracellular infections, such as those caused by the protozoan parasite Leishmania donovani, a causative agent of visceral leishmaniasis (VL), require a potent host proinflammatory response for control. IL-17 has emerged as an important proinflammat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a51b3d52ba350810bdad936836a6deb
https://doi.org/10.4049/jimmunol.1501046
https://doi.org/10.4049/jimmunol.1501046
Autor:
Rhiannon B. Werder, Shannon E. Best, Fabian de Labastida Rivera, Ashraful Haque, Simon Phipps, Fiona H. Amante, Chelsea L. Edwards, Rebecca J. Faleiro, Kylie R. James, Ismail Sebina, Christian R. Engwerda, Vivian Zhang
Publikováno v:
Clinical and Vaccine Immunology. 22:477-483
Acute lower respiratory tract infections (ALRTI) are the leading cause of global childhood mortality, with human respiratory syncytial virus (hRSV) being a major cause of viral ALRTI in young children worldwide. In sub-Saharan Africa, many young chil
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3694db6c16eecd2e1431e909554c0733
https://doi.org/10.1128/cvi.00051-15
https://doi.org/10.1128/cvi.00051-15
Autor:
Megan S. F. Soon, Kylie R. James, Bryce S. Thomas, Ashraful Haque, Shannon E. Best, Jasmin Akter, David S. Khoury, Miles P. Davenport, Ismail Sebina, Deborah Cromer, Trish Elliott
Severe malaria and associated high parasite burdens occur more frequently in humans lacking robust adaptive immunity to Plasmodium falciparum Nevertheless, the host may partly control blood-stage parasite numbers while adaptive immunity is gradually
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b7b52db4b6b6ca8227bb28fe8f98306d
https://europepmc.org/articles/PMC5530648/
https://europepmc.org/articles/PMC5530648/
