Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Shannon D. Barker"'
Autor:
Shannon D. Barker, Timothy E. Allen
Publikováno v:
Biomedical Engineering Education
The COVID-19 induced abrupt transition to online learning that occurred in the Spring of 2020 presented particular challenges to the adaptation of hands-on laboratory courses in biomedical engineering. This paper describes the transition of such a co
Autor:
Christina Bridges, Ramaswamy K. Iyer, Lisa V. Kalman, Pinar Bayrak-Toydemir, Jack Tarleton, Shannon D. Barker, Arlene Buller-Burckle, Lorraine Toji, Sherri J. Bale, Soma Das, Timothy D. Vo, Val V. Zvereff, Alan K. Percy, Swaroop Aradhya
Publikováno v:
The Journal of Molecular Diagnostics. 16(2):273-279
Rett syndrome is a dominant X-linked disorder caused by point mutations (approximately 80%) or by deletions or insertions (approximately 15% to 18%) in the MECP2 gene. It is most common in females but lethal in males, with a distinctly different phen
Autor:
Barbara A. Zehnbauer, Ira M. Lubin, Shannon D. Barker, Sue Richards, Iris Schrijver, Lisa V. Kalman, Desirée du Sart, Mario Pazzagli, Rob Elles, Wayne W. Grody
Publikováno v:
Archives of Pathology & Laboratory Medicine. 137:983-988
Participation in proficiency testing (PT) or external quality assessment (EQA) programs allows the assessment and comparison of test performance among different clinical laboratories and technologies. In addition to the approximately 2300 tests for i
Autor:
Michele Caggana, Elizabeth M. Rohlfs, Shannon D. Barker, Victoria M. Pratt, Kasinathan Muralidharan, W. Edward Highsmith, Lisa V. Kalman, Leonard M. Holtegaard, Christina Bridges, Jack Tarleton, Arlene Buller, Lorraine Toji, Lisa DiAntonio
Publikováno v:
The Journal of Molecular Diagnostics. 11:186-193
The number of different laboratories that perform genetic testing for cystic fibrosis is increasing. However, there are a limited number of quality control and other reference materials available, none of which cover all of the alleles included in co
Autor:
Hidetaka Ono, Paul N. Reynolds, Chikara Kunisaki, Yasuo Adachi, David T. Curiel, Masato Yamamoto, Julia Davydova, Hiroshi Shimada, Shannon D. Barker, Koichi Takayama, Victor Krasnykh
Publikováno v:
Journal of Gastroenterology. 40:31-42
Gastric cancer is the fourth most common malignancy worldwide. Adenoviral vectors (Ads) have been applied for gene therapy of various cancers because of their high transduction efficiency. However, the infectivity of gastrointestinal cancer cells is
Autor:
Ronald D. Alvarez, B. Liu, Angel A. Rivera, Akseli Hemminki, Dirk M. Nettelbeck, Shannon D. Barker, Igor Dmitriev, David T. Curiel
Publikováno v:
Gene Therapy. 10:1198-1204
Adenoviruses are efficient gene delivery vehicles but have broad native tropism. To this end, finding ways to target this virus specifically to carcinomas has become an important focus of cancer gene therapy. Transductional and transcriptional forms
Autor:
J. Michael Straughn, Minghui Wang, John T. Lam, Anna Kanerva, Jerry L. Blackwell, David T. Curiel, Ronald D. Alvarez, Mack N. Barnes, Shannon D. Barker, Akseli Hemminki, Gene P. Siegal, Gerd J. Bauerschmitz
Publikováno v:
Cancer Gene Therapy. 10:377-387
Replication competent viruses hold promise for treatment of advanced cancers resistant to available therapeutic modalities. Although preliminary clinical results have substantiated their efficacy, preclinical development of these novel approaches is
Autor:
Victor Krasnykh, Yasuo Adachi, Julia Davydova, David T. Curiel, Koichi Takayama, Shannon D. Barker, Masato Yamamoto, Selwyn M. Vickers, Peter Nagi
Publikováno v:
Journal of Gastrointestinal Surgery. 7:364-371
Cholangiocarcinoma is an invasive malignancy that is most often unresectable upon diagnosis and unresponsive to chemotherapy and radiation. While adenoviral gene therapy has shown promise in treating many tumors, systemic toxicity and low tumor trans
Autor:
Gene P. Siegal, David T. Curiel, Dirk M. Nettelbeck, Shannon D. Barker, Waleed Arafat, Parameshwar J. Mahasreshti, M. Wang, Mack N. Barnes, Akseli Hemminki, Enrique Casado, Donald J. Buchsbaum, Jialing Xiang, Jesus Gomez-Navarro, Ronald D. Alvarez, Hidde J. Haisma
Publikováno v:
Gene Therapy, 9(4), 256-262. Nature Publishing Group
Single chain antibodies (scFv) represent powerful interventional agents for the achievement of targeted therapeutics. The practical utility of these agents have been limited, however, by difficulties related to production of recombinant scFv and the
Autor:
Bin Liu, Jesus Gomez-Navarro, Shannon D. Barker, Gene P. Siegal, Jialing Xiang, David T. Curiel, Waleed Arafat, Ronald D. Alvarez
Publikováno v:
The Journal of Gene Medicine. 2:97-106
Background Tumor cell heterogeneity and resistance to chemotherapy-mediated cell death are major obstacles in cancer therapy. It has been reported that expression of the pro-apoptotic molecule Bax can induce cell death or sensitize tumor cells to che