Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Shannon C. Kelly"'
Autor:
Jiameng Sun, Yiming Zhang, Joshua A. Adams, Cassandra B. Higgins, Shannon C. Kelly, Hao Zhang, Kevin Y. Cho, Ulysses G. Johnson, Benjamin M. Swarts, Shun-Ichi Wada, Gary J. Patti, Leah P. Shriver, Brian N. Finck, Erik D. Herzog, Brian J. DeBosch
Publikováno v:
Cell Reports, Vol 43, Iss 10, Pp 114865- (2024)
Summary: Organisms integrate circadian and metabolic signals to optimize substrate selection to survive starvation, yet precisely how this occurs is unclear. Here, we show that hepatocyte Period 1 (Per1) is selectively induced during fasting, and mic
Externí odkaz:
https://doaj.org/article/f3f84b6930c6468d8267aafa1547506a
Autor:
Yiming Zhang, Jiameng Sun, Henry D. Wasserman, Joshua A. Adams, Cassandra B. Higgins, Shannon C. Kelly, Louise Lantier, Brian J. DeBosch
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 17, Iss 5, Pp 801-820 (2024)
Background & Aims: Restoring hepatic and peripheral insulin sensitivity is critical to prevent or reverse metabolic syndrome and type 2 diabetes. Glucose homeostasis comprises in part the complex regulation of hepatic glucose production and insulin-m
Externí odkaz:
https://doaj.org/article/c22f4337f0d34c74a26c716f33616718
Autor:
Mohamed Zaid, Lorenzo Sala, Jan R. Ivey, Darla L. Tharp, Christina M. Mueller, Pamela K. Thorne, Shannon C. Kelly, Kleiton Augusto Santos Silva, Amira R. Amin, Pilar Ruiz-Lozano, Michael S. Kapiloff, Laurel Despins, Mihail Popescu, James Keller, Marjorie Skubic, Salman Ahmad, Craig A. Emter, Giovanna Guidoboni
Publikováno v:
Frontiers in Medical Technology, Vol 4 (2022)
Left ventricular (LV) catheterization provides LV pressure-volume (P-V) loops and it represents the gold standard for cardiac function monitoring. This technique, however, is invasive and this limits its applicability in clinical and in-home settings
Externí odkaz:
https://doaj.org/article/c8d1c5d427c24c598af79f22e9e6a80e
Publikováno v:
Redox Biology, Vol 27, Iss , Pp - (2019)
The reduction of extracellular oxidants by intracellular electrons is known as trans-plasma membrane electron transport (tPMET). The goal of this study was to characterize a role of tPMET in the sensing of glucose as a physiological signal. tPMET fro
Externí odkaz:
https://doaj.org/article/22e11ebedf6640d2a20621a19d730915
Autor:
Gordon I. Smith, Jun Yoshino, Shannon C. Kelly, Dominic N. Reeds, Adewole Okunade, Bruce W. Patterson, Samuel Klein, Bettina Mittendorfer
Publikováno v:
Cell Reports, Vol 17, Iss 3, Pp 849-861 (2016)
High-protein (HP) intake during weight loss (WL) therapy is often recommended because it reduces the loss of lean tissue mass. However, HP intake could have adverse effects on metabolic function, because protein ingestion reduces postprandial insulin
Externí odkaz:
https://doaj.org/article/76d10f73415545cdabce7bead19360cc
Autor:
Kelly L. Stromsdorfer, Shintaro Yamaguchi, Myeong Jin Yoon, Anna C. Moseley, Michael P. Franczyk, Shannon C. Kelly, Nathan Qi, Shin-ichiro Imai, Jun Yoshino
Publikováno v:
Cell Reports, Vol 16, Iss 7, Pp 1851-1860 (2016)
Obesity is associated with adipose tissue dysfunction and multi-organ insulin resistance. However, the mechanisms of such obesity-associated systemic metabolic complications are not clear. Here, we characterized mice with adipocyte-specific deletion
Externí odkaz:
https://doaj.org/article/ee35fd484f664b6aaf26e2f9d3f0e0d3
Autor:
Amanda M. Eccardt, Thomas P. Bell, Lyn Mattathil, Rohan Prasad, Shannon C. Kelly, Jonathan S. Fisher
Publikováno v:
Antioxidants, Vol 6, Iss 4, p 89 (2017)
Trans-plasma membrane electron transport (tPMET) and the antioxidant roles of ascorbate reportedly play a role in protection of cells from damage by reactive oxygen species, which have been implicated in causing metabolic dysfunction such as insulin
Externí odkaz:
https://doaj.org/article/6214ed887a6640e9b4c565864170b37b
Publikováno v:
Journal of Applied Physiology. 134:482-489
This retrospective analysis evaluated the impact of exercise, sex, and diet on ACE2 and TMPRSS2 mRNA levels in preclinical swine heart failure models. Unlike normal exercise intensities, exercise training of an intensity tolerable to a patient with h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::37f8556a54653c8a6ad4741815d1f3cc
https://doi.org/10.1152/japplphysiol.00736.2022
https://doi.org/10.1152/japplphysiol.00736.2022
Autor:
Jinliang Li, Shannon C. Kelly, Jan R. Ivey, Pamela K. Thorne, Kelly P. Yamada, Tadao Aikawa, Renata Mazurek, James R. Turk, Kleiton Augusto Santos Silva, Amira R. Amin, Darla L. Tharp, Christina M. Mueller, Hrishikesh Thakur, Emily V. Leary, Timothy L. Domeier, R. Scott Rector, Kenneth Fish, Federico Cividini, Kiyotake Ishikawa, Craig A. Emter, Michael S. Kapiloff
Publikováno v:
Physiol Genomics
Limited reports exist regarding adeno-associated virus (AAV) biodistribution in swine. This study assessed biodistribution following antegrade intracoronary and intravenous delivery of two self-complementary serotype 9 AAV (AAV9sc) biologics designed
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b0e3ddf76605f364784356e1691fe34
https://doi.org/10.1152/physiolgenomics.00032.2022
https://doi.org/10.1152/physiolgenomics.00032.2022
Publikováno v:
The FASEB Journal. 36
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2db9a22adfd12172e31f69ff7318ae66
https://doi.org/10.1096/fasebj.2022.36.s1.r5112
https://doi.org/10.1096/fasebj.2022.36.s1.r5112