Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Shannon A Bryan"'
Autor:
Jennifer L. McGRATH, Jamey Khan, David A Okrongly, Ann Dewar, John F. Burman, Shannon A Bryan, Trevor T. Hansel, Peter J. Barnes, Margaret J Leckie, Sarah L. Aikman
Publikováno v:
Thorax. 55:471-477
Background—Asthma has been associated with eosinophil activation, measured in serum, sputum, bronchoalveolar lavage (BAL) fluid, and urine. A whole blood automated method was developed to assess eosinophil and neutrophil activity in terms of peroxi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f44377025179cbca98a143fb987525b
https://doi.org/10.1136/thorax.55.6.471
https://doi.org/10.1136/thorax.55.6.471
Autor:
Peter J. Barnes, Ian Sabroe, Gavin R. Jenkins, Timothy J. Williams, Trevor T. Hansel, Margaret J Leckie, Shannon A Bryan
During the Phase I/II assessment of new therapies with the potential to suppress eosinophil and neutrophil inflammation, there is a need to assess the peripheral blood pharmacokinetic (PK) and pharmacodynamic (PD) profiles of the drug. This has relev
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3e7732cfa4fc5a0ed6504d128e8c1210
https://doi.org/10.1385/1-59259-151-5:345
https://doi.org/10.1385/1-59259-151-5:345
Autor:
Joanna R. Topping, Peter J. Jose, Robert Stephen Wilhelm, Carol Soderberg, Trevor T. Hansel, Timothy J. Williams, Denis John Kertesz, Shannon A Bryan, Peter J. Barnes, Ian Sabroe
Publikováno v:
American journal of respiratory and critical care medicine. 165(12)
CC-chemokine receptor 3 (CCR3)-stimulating chemokines are likely to have important in vivo roles in the regulation of eosinophil, basophil, and potentially helper T cell type 2 and mast cell recruitment. We have developed techniques to investigate th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6095faff99ea13f283d211e7aefa2837
https://pubmed.ncbi.nlm.nih.gov/12070060
https://pubmed.ncbi.nlm.nih.gov/12070060
Publikováno v:
Expert opinion on investigational drugs. 9(1)
The health burden of asthma is increasing globally at an alarming rate, providing a strong impetus for the development of new therapeutics. Currently available inhaled bronchodilators and anti-inflammatory drugs are effective in most asthmatics, but
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dd7ec4b1a24fba18ea2cfaa7f011ef25
https://pubmed.ncbi.nlm.nih.gov/11060658
https://pubmed.ncbi.nlm.nih.gov/11060658
Publikováno v:
Expert opinion on investigational drugs. 9(1)
The incidence of chronic obstructive pulmonary disease (COPD) is increasing throughout the world. Much less is known about the pathogenesis of COPD than that of asthma and there is little response to current therapy. Most patients with COPD have acqu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eacb51867c4dc79cd95ce74304e4e1a7
https://pubmed.ncbi.nlm.nih.gov/11060657
https://pubmed.ncbi.nlm.nih.gov/11060657