Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Shannon, Nicolson"'
Autor:
Shannon Nicolson, Jantina A. Manning, Yoon Lim, Xin Jiang, Erica Kolze, Sonia Dayan, Ruchi Umargamwala, Tianqi Xu, Jarrod J. Sandow, Andrew I. Webb, Sharad Kumar, Donna Denton
Publikováno v:
Communications Biology, Vol 7, Iss 1, Pp 1-24 (2024)
Abstract Autophagy, the process of elimination of cellular components by lysosomal degradation, is essential for animal development and homeostasis. Using the autophagy-dependent Drosophila larval midgut degradation model we identified an autophagy r
Externí odkaz:
https://doaj.org/article/48b9fe21c5fc45f2b5b559b3895df865
Autor:
Andrew I. Webb, Shannon Nicolson, Xin Jiang, Donna Denton, Sharad Kumar, Jarrod J. Sandow, Sonia Dayan, Tianqi Xu, Jantina A. Manning
Publikováno v:
Autophagy. 17:2734-2749
Macroautophagy/autophagy is a highly conserved lysosomal degradative pathway important for maintaining cellular homeostasis. Much of our current knowledge of autophagy is focused on the initiation steps in this process. Recently, an understanding of
Autor:
Tianqi, Xu, Shannon, Nicolson, Jarrod J, Sandow, Sonia, Dayan, Xin, Jiang, Jantina A, Manning, Andrew I, Webb, Sharad, Kumar, Donna, Denton
Publikováno v:
Autophagy
Macroautophagy/autophagy is a highly conserved lysosomal degradative pathway important for maintaining cellular homeostasis. Much of our current knowledge of autophagy is focused on the initiation steps in this process. Recently, an understanding of
Publikováno v:
PLoS ONE, Vol 7, Iss 10, p e47447 (2012)
The spindle assembly checkpoint is crucial for the maintenance of a stable chromosome number. Defects in the checkpoint lead to Chromosomal INstability (CIN), which is linked to the progression of tumors with poor clinical outcomes such as drug resis
Externí odkaz:
https://doaj.org/article/f64353e28f654ddd994fa0b5a4be267d
Publikováno v:
Cell Death and Differentiation
Animal development and homeostasis require the programmed removal of cells. Autophagy-dependent cell deletion is a unique form of cell death often involved in bulk degradation of tissues. In Drosophila the steroid hormone ecdysone controls developmen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::590043b551a515c6d9bee7315b1ae4a0
https://hdl.handle.net/11541.2/132835
https://hdl.handle.net/11541.2/132835
Publikováno v:
Cell Death & Disease
Cell Death and Disease, Vol 10, Iss 2, Pp 1-8 (2019)
Cell Death and Disease, Vol 10, Iss 2, Pp 1-8 (2019)
The majority of developmentally programmed cell death (PCD) is mediated by caspase-dependent apoptosis; however, additional modalities, including autophagy-dependent cell death, have important spatiotemporally restricted functions. Autophagy involves
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c6e1841e65f586f245bc6deb91db5e8c
https://hdl.handle.net/11541.2/136044
https://hdl.handle.net/11541.2/136044
Publikováno v:
Cell Death & Differentiation. 19:87-95
Autophagy (the process of self-digestion by a cell through the action of enzymes originating within the lysosome of the same cell) is a catabolic process that is generally used by the cell as a mechanism for quality control and survival under nutrien
Publikováno v:
The International journal of developmental biology. 59(1-3)
During Drosophila development, the steroid hormone ecdysone plays a key role in the transition from embryo into larva and then into pupa. It is during larval-pupal metamorphosis that extensive programmed cell death occurs to remove large obsolete lar
Autor:
Shannon Nicolson, Sharad Kumar, Kathryn Mills, Wenying Zhu, May T. Aung-Htut, Nirmal Lorensuhewa, Dimitrios Cakouros, Andreas Bergmann, Donna Denton
Correct spatial and temporal induction of numerous cell type-specific genes during development requires regulated removal of the repressive histone H3 lysine 27 trimethylation (H3K27me3) modification. Here we show that the H3K27me3 demethylase dUTX i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a632da81620dd8ed2945691b96428d32
https://hdl.handle.net/1959.8/155445
https://hdl.handle.net/1959.8/155445
Publikováno v:
PLoS ONE
PLoS ONE, Vol 7, Iss 10, p e47447 (2012)
PLoS ONE, Vol 7, Iss 10, p e47447 (2012)
Background: The spindle assembly checkpoint is crucial for the maintenance of a stable chromosome number. Defects in the checkpoint lead to Chromosomal INstability (CIN), which is linked to the progression of tumors with poor clinical outcomes such a