Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Shann S, Yu"'
Autor:
Lisa R. Volpatti, Rachel P. Wallace, Shijie Cao, Michal M. Raczy, Ruyi Wang, Laura T. Gray, Aaron T. Alpar, Priscilla S. Briquez, Nikolaos Mitrousis, Tiffany M. Marchell, Maria Stella Sasso, Mindy Nguyen, Aslan Mansurov, Erica Budina, Ani Solanki, Elyse A. Watkins, Mathew R. Schnorenberg, Andrew C. Tremain, Joseph W. Reda, Vlad Nicolaescu, Kevin Furlong, Steve Dvorkin, Shann S. Yu, Balaji Manicassamy, James L. LaBelle, Matthew V. Tirrell, Glenn Randall, Marcin Kwissa, Melody A. Swartz, Jeffrey A. Hubbell
Publikováno v:
ACS Central Science, Vol 7, Iss 8, Pp 1368-1380 (2021)
Externí odkaz:
https://doaj.org/article/7d6f01c438c547eb843b88a5c03b6825
Lymphatic endothelial cells prime naïve CD8+ T cells into memory cells under steady-state conditions
Autor:
Efthymia Vokali, Shann S. Yu, Sachiko Hirosue, Marcela Rinçon-Restrepo, Fernanda V. Duraes, Stefanie Scherer, Patricia Corthésy-Henrioud, Witold W. Kilarski, Anna Mondino, Dietmar Zehn, Stéphanie Hugues, Melody A. Swartz
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-18 (2020)
Lymphatic endothelial cells (LECs) can cross-present antigen to naïve CD8+ T cells, but the significance of this interaction was unclear. Here the authors show that LECs directly induce CD8+ T cell differentiation with memory-like phenotypes, migrat
Externí odkaz:
https://doaj.org/article/f23b98b899c044b5baa15c4c746b6da2
Autor:
Laura T. Gray, Glenn Randall, Mindy Nguyen, Matthew Tirrell, Marcin Kwissa, Steve Dvorkin, Aaron T. Alpar, Balaji Manicassamy, Jeffrey A. Hubbell, Nikolaos Mitrousis, Elyse A. Watkins, James L. LaBelle, Tiffany M. Marchell, Erica Budina, Shann S. Yu, Shijie Cao, Ruyi Wang, Rachel P. Wallace, Michal M. Raczy, Mathew R. Schnorenberg, Kevin Furlong, Vlad Nicolaescu, Lisa R. Volpatti, Andrew C Tremain, Melody A. Swartz, Joseph W. Reda, Aslan Mansurov, Maria Stella Sasso, Priscilla S. Briquez, Ani Solanki
Publikováno v:
ACS Central Science, Vol 7, Iss 8, Pp 1368-1380 (2021)
bioRxiv
article-version (status) pre
article-version (number) 1
ACS Central Science
bioRxiv
article-version (status) pre
article-version (number) 1
ACS Central Science
The COVID-19 pandemic underscores the need for rapid, safe, and effective vaccines. In contrast to some traditional vaccines, nanoparticle-based subunit vaccines are particularly efficient in trafficking antigens to lymph nodes, where they induce pot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::00eb21cfa353bc8b2d6928782bffd622
https://doaj.org/article/7d6f01c438c547eb843b88a5c03b6825
https://doaj.org/article/7d6f01c438c547eb843b88a5c03b6825
Publikováno v:
Drug Delivery and Translational Research. 11:2273-2275
Immunotherapies are designed to treat disease by modulating the activity of immune cells. Here, we consider how anatomy and microphysiology create transport barriers to immunotherapeutic delivery and retention at diseased sites, and summarize recent
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e4da8b841e81449c7f4168d278c154fd
https://doi.org/10.1007/s13346-021-01084-4
https://doi.org/10.1007/s13346-021-01084-4
Publikováno v:
Drug delivery and translational research. 11(6)
Immunotherapies are designed to treat disease by modulating the activity of immune cells. Here, we consider how anatomy and microphysiology create transport barriers to immunotherapeutic delivery and retention at diseased sites, and summarize recent
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::361930eaf758345dce6a2bf126ce2e7a
https://pubmed.ncbi.nlm.nih.gov/34718959
https://pubmed.ncbi.nlm.nih.gov/34718959
Autor:
Tiffany M. Marchell, Nikolaos Mitrousis, Ruyi Wang, Laura T. Gray, Glenn Randall, Melody A. Swartz, Marcin Kwissa, Rachel P. Wallace, Kevin Furlong, Vlad Nicolaescu, Michal M. Raczy, Mindy Nguyen, Elyse A. Watkins, Balaji Manicassamy, Andrew C Tremain, D. Scott Wilson, Lisa R. Volpatti, Ani Solanki, Steve Dvorkin, Maria Stella Sasso, Shijie Cao, Erica Budina, Aaron T. Alpar, Jeffrey A. Hubbell, Joseph W. Reda, Aslan Mansurov, Priscilla S. Briquez, Shann S. Yu
The SARS-CoV-2 virus has caused an unprecedented global crisis, and curtailing its spread requires an effective vaccine which elicits a diverse and robust immune response. We have previously shown that vaccines made of a polymeric glyco-adjuvant conj
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::609dc88b5ac6a29a8652cb34dab4d818
https://doi.org/10.1101/2021.05.20.445060
https://doi.org/10.1101/2021.05.20.445060
Autor:
Ani Solanki, Marcin Kwissa, Andrew C Tremain, Vlad Nicolaescu, Aaron T. Alpar, Nikolaos Mitrousis, Melody A. Swartz, Lisa R. Volpatti, Shann S. Yu, Rachel P. Wallace, Matthew Tirrell, Ruyi Wang, Elyse A. Watkins, Maria Stella Sasso, Tiffany M. Marchell, Balaji Manicassamy, Michal M. Raczy, Shijie Cao, Steve Dvorkin, Joseph W. Reda, Aslan Mansurov, Priscilla S. Briquez, Kevin Furlong, Mathew R. Schnorenberg, Glenn Randall, Erica Budina, Mindy Nguyen, Laura T. Gray, Jeffrey A. Hubbell, James L. LaBelle
A diverse portfolio of SARS-CoV-2 vaccine candidates is needed to combat the evolving COVID-19 pandemic. Here, we developed a subunit nanovaccine by conjugating SARS-CoV-2 Spike protein receptor binding domain (RBD) to the surface of oxidation-sensit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f29e4a1f213b1a04920be54ae8e85047
https://doi.org/10.1101/2021.04.08.438884
https://doi.org/10.1101/2021.04.08.438884
Lymphatic endothelial cells prime naïve CD8+ T cells into memory cells under steady-state conditions
Autor:
Stefanie Scherer, Melody A. Swartz, Marcela Rincon-Restrepo, Stéphanie Hugues, Efthymia Vokali, Witold W. Kilarski, Sachiko Hirosue, Dietmar Zehn, Anna Mondino, Patricia Corthésy-Henrioud, Fernanda V. Duraes, Shann S. Yu
Publikováno v:
Nature Communications
Nature Communications, Vol 11, Iss 1, Pp 1-18 (2020)
Nature Communications, Vol. 11, No 1 (2020) P. 538
Nature Communications, Vol 11, Iss 1, Pp 1-18 (2020)
Nature Communications, Vol. 11, No 1 (2020) P. 538
Lymphatic endothelial cells (LECs) chemoattract naïve T cells and promote their survival in the lymph nodes, and can cross-present antigens to naïve CD8+ T cells to drive their proliferation despite lacking key costimulatory molecules. However, the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::718400f022630378a2c95e8658dd96e8
Autor:
Mukesh K. Gupta, Joel M. Walthall, Raghav Venkataraman, Spencer W. Crowder, Dae Kwang Jung, Shann S. Yu, Tromondae K. Feaster, Xintong Wang, Todd D. Giorgio, Charles C. Hong, Franz J. Baudenbacher, Antonis K. Hatzopoulos, Hak-Joon Sung
Publikováno v:
PLoS ONE, Vol 7, Iss 9 (2012)
Externí odkaz:
https://doaj.org/article/cd461aa6dddb449692cd9abb95cf879b
Autor:
Mukesh K Gupta, Joel M Walthall, Raghav Venkataraman, Spencer W Crowder, Dae Kwang Jung, Shann S Yu, Tromondae K Feaster, Xintong Wang, Todd D Giorgio, Charles C Hong, Franz J Baudenbacher, Antonis K Hatzopoulos, Hak-Joon Sung
Publikováno v:
PLoS ONE, Vol 6, Iss 12, p e28935 (2011)
Myocardial infarction results in extensive cardiomyocyte death which can lead to fatal arrhythmias or congestive heart failure. Delivery of stem cells to repopulate damaged cardiac tissue may be an attractive and innovative solution for repairing the
Externí odkaz:
https://doaj.org/article/5d700bf19d284914824bbd4f60dc8edd