Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Shanliang SUN"'
Autor:
Xuejiao Leng, Mengyuan Zhang, Yujing Xu, Jingjing Wang, Ning Ding, Yancheng Yu, Shanliang Sun, Weichen Dai, Xin Xue, Nianguang Li, Ye Yang, Zhihao Shi
Publikováno v:
Journal of Pharmaceutical Analysis, Vol 14, Iss 7, Pp 100947- (2024)
Cancer genomics has led to the discovery of numerous oncogenes and tumor suppressor genes that play critical roles in cancer development and progression. Oncogenes promote cell growth and proliferation, whereas tumor suppressor genes inhibit cell gro
Externí odkaz:
https://doaj.org/article/cd579f505e98476080e5ff80598e5220
Autor:
Yuqian Yuan, Xiaozhu Tang, Hongyan Li, Xufeng Lang, Can Li, Yihua Song, Shanliang Sun, Ye Yang, Zuojian Zhou
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
Due to the similarity and diversity among kinases, small molecule kinase inhibitors (SMKIs) often display multi-target effects or selectivity, which have a strong correlation with the efficacy and safety of these inhibitors. However, due to the limit
Externí odkaz:
https://doaj.org/article/455f26cca0194c02b9134b0674f7538c
Autor:
Xiaolin Sun, Chaorui Guo, Chunyan Huang, Ning Lv, Huili Chen, Haoyan Huang, Yulin Zhao, Shanliang Sun, Di Zhao, Jingwei Tian, Xijing Chen, Yongjie Zhang
Publikováno v:
Redox Biology, Vol 71, Iss , Pp 103116- (2024)
Oxidative stress plays an important role in the pathogenesis of acute lung injury (ALI). As a typical post-translational modification triggered by oxidative stress, protein S-glutathionylation (PSSG) is regulated by redox signaling pathways and plays
Externí odkaz:
https://doaj.org/article/15a23e4295e04d80a5dfcc6924adcc6c
Autor:
Chunyan Gu, Yajun Wang, Lulin Zhang, Li Qiao, Shanliang Sun, Miaomiao Shao, Xiaozhu Tang, Pinggang Ding, Chao Tang, Yuhao Cao, Yanyan Zhou, Mengjie Guo, Rongfang Wei, Nianguang Li, Yibei Xiao, Jinao Duan, Ye Yang
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 42, Iss 1, Pp 1-4 (2023)
Externí odkaz:
https://doaj.org/article/60981aa57de3419294bc8419b6f812fa
Autor:
Chao Tang, Mengying Ke, Xichao Yu, Shanliang Sun, Xian Luo, Xin Liu, Yanyan Zhou, Ze Wang, Xing Cui, Chunyan Gu, Ye Yang
Publikováno v:
Advanced Science, Vol 10, Iss 25, Pp n/a-n/a (2023)
Abstract Tumor stemness is associated with the recurrence and incurability of colorectal cancer (CRC), which lacks effective therapeutic targets and drugs. Glycinamide ribonucleotide transformylase (GART) fulfills an important role in numerous types
Externí odkaz:
https://doaj.org/article/726183e25c3f49f1b7d9b543ef59bcbc
Autor:
Chunyan Gu, Yajun Wang, Lulin Zhang, Li Qiao, Shanliang Sun, Miaomiao Shao, Xiaozhu Tang, Pinggang Ding, Chao Tang, Yuhao Cao, Yanyan Zhou, Mengjie Guo, Rongfang Wei, Nianguang Li, Yibei Xiao, Jinao Duan, Ye Yang
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 41, Iss 1, Pp 1-14 (2022)
Abstract Background Currently, multiple myeloma (MM) is still an incurable plasma cell malignancy in urgent need of novel therapeutic targets and drugs. Methods Bufalin was known as a highly toxic but effective anti-cancer compound. We used Bufalin a
Externí odkaz:
https://doaj.org/article/ae3d76e7c1924ac494159517a84e8a2a
Autor:
Yuanjiao Zhang, Zhendong Deng, Shanliang Sun, Siyuan Xie, Mingmei Jiang, Bing Chen, Chunyan Gu, Ye Yang
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
Multiple myeloma (MM) is a clinically distinctive plasma cell malignancy in the bone marrow (BM), in which epigenetic abnormalities are featured prominently. Epigenetic modifications including acetylation have been deemed to contribute to tumorigenes
Externí odkaz:
https://doaj.org/article/b07a06c8ddcb414da5d9e1109a4b3e17
Autor:
Xavier Gómez-Santacana, Sabrina M. de Munnik, Tamara A. M. Mocking, Niels J. Hauwert, Shanliang Sun, Prashanna Vijayachandran, Iwan J. P. de Esch, Henry F. Vischer, Maikel Wijtmans, Rob Leurs
Publikováno v:
Beilstein Journal of Organic Chemistry, Vol 15, Iss 1, Pp 2509-2523 (2019)
We report a detailed structure–activity relationship for the scaffold of VUF16216, a compound we have previously communicated as a small-molecule efficacy photoswitch for the peptidergic chemokine GPCR CXCR3. A series of photoswitchable azobenzene
Externí odkaz:
https://doaj.org/article/191d27a959cf464cbd751133e1acc2e9
Publikováno v:
Chinese Journal of Lung Cancer, Vol 12, Iss 2, Pp 106-110 (2009)
Background and objective Although there are increasing reports on localization of tracheal stem cells, the mechanism of proliferation and differentiation of tracheal stem cells remains unclear. Methods In this study, we developed an ex vivo model of
Externí odkaz:
https://doaj.org/article/e5732f3b12374af4b67dba9a8ee9de4e
Autor:
Xiang Chen, Luyao Han, Yulin Zhao, Haoyan Huang, He Pan, Chenmeng Zhang, Huili Chen, Shanliang Sun, Sihui Yao, Xijing Chen, Yongjie Zhang
Publikováno v:
Drug Metabolism and Disposition. 51:771-781
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2aefcc741ba403d6c2c8beabfd399015
https://doi.org/10.1124/dmd.122.001245
https://doi.org/10.1124/dmd.122.001245