Zobrazeno 1 - 10
of 50
pro vyhledávání: '"Shankha Satpathy"'
Autor:
Jennifer G. Abelin, Erik J. Bergstrom, Keith D. Rivera, Hannah B. Taylor, Susan Klaeger, Charles Xu, Eva K. Verzani, C. Jackson White, Hilina B. Woldemichael, Maya Virshup, Meagan E. Olive, Myranda Maynard, Stephanie A. Vartany, Joseph D. Allen, Kshiti Phulphagar, M. Harry Kane, Suzanna Rachimi, D. R. Mani, Michael A. Gillette, Shankha Satpathy, Karl R. Clauser, Namrata D. Udeshi, Steven A. Carr
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-22 (2023)
Patient samples are often available in limited amounts, restricting the number of possible omics analyses. Here the authors present MONTE, a workflow that enables serial HLA-I and HLA-II immunopeptidome, ubiquitylome, proteome, phosphoproteome, and a
Externí odkaz:
https://doaj.org/article/2cb22e1fb42e4c8ab1737bea5ee8836a
Autor:
Hasmik Keshishian, E Robert McDonald, Filip Mundt, Randy Melanson, Karsten Krug, Dale A Porter, Luke Wallace, Dominique Forestier, Bokang Rabasha, Sara E Marlow, Judit Jane‐Valbuena, Ellen Todres, Harrison Specht, Margaret Lea Robinson, Pierre M Jean Beltran, Ozgun Babur, Meagan E Olive, Javad Golji, Eric Kuhn, Michael Burgess, Melanie A MacMullan, Tomas Rejtar, Karen Wang, DR Mani, Shankha Satpathy, Michael A Gillette, William R Sellers, Steven A Carr
Publikováno v:
Molecular Systems Biology, Vol 17, Iss 9, Pp 1-22 (2021)
Abstract Reliable methods to quantify dynamic signaling changes across diverse pathways are needed to better understand the effects of disease and drug treatment in cells and tissues but are presently lacking. Here, we present SigPath, a targeted mas
Externí odkaz:
https://doaj.org/article/8c21ac714ff142d89c9c58dde8847a35
Autor:
Shankha Satpathy, Eric J. Jaehnig, Karsten Krug, Beom-Jun Kim, Alexander B. Saltzman, Doug W. Chan, Kimberly R. Holloway, Meenakshi Anurag, Chen Huang, Purba Singh, Ari Gao, Noel Namai, Yongchao Dou, Bo Wen, Suhas V. Vasaikar, David Mutch, Mark A. Watson, Cynthia Ma, Foluso O. Ademuyiwa, Mothaffar F. Rimawi, Rachel Schiff, Jeremy Hoog, Samuel Jacobs, Anna Malovannaya, Terry Hyslop, Karl R. Clauser, D. R. Mani, Charles M. Perou, George Miles, Bing Zhang, Michael A. Gillette, Steven A. Carr, Matthew J. Ellis
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-16 (2020)
Connecting genomics and proteomics allows the development of more efficient and specific treatments for cancer. Here, the authors develop proteogenomic methods to defining cancer signaling in-vivo starting from core needle biopsies and with applicati
Externí odkaz:
https://doaj.org/article/1139337b9d47460b818a84e3816a1de9
Autor:
Namrata D. Udeshi, Deepak C. Mani, Shankha Satpathy, Shaunt Fereshetian, Jessica A. Gasser, Tanya Svinkina, Meagan E. Olive, Benjamin L. Ebert, Philipp Mertins, Steven A. Carr
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-11 (2020)
Comprehensive protein ubiquitylation profiling by mass spectrometry typically requires large sample amounts, limiting its applicability to tissue samples. Here, the authors present an optimized proteomics method that enables multiplexed ubiquitylome
Externí odkaz:
https://doaj.org/article/68ca13e669fe40e6b40606c8ff538f1d
Autor:
Shankha Satpathy, Sebastian A Wagner, Petra Beli, Rajat Gupta, Trine A Kristiansen, Dessislava Malinova, Chiara Francavilla, Pavel Tolar, Gail A Bishop, Bruce S Hostager, Chunaram Choudhary
Publikováno v:
Molecular Systems Biology, Vol 11, Iss 6, Pp 1-22 (2015)
Abstract B‐cell receptor (BCR) signaling is essential for the development and function of B cells; however, the spectrum of proteins involved in BCR signaling is not fully known. Here we used quantitative mass spectrometry‐based proteomics to mon
Externí odkaz:
https://doaj.org/article/6e9e558b60ec42e8b4adc1da130fe1df
Autor:
Meenakshi Anurag, Eric J. Jaehnig, Karsten Krug, Jonathan T. Lei, Erik J. Bergstrom, Beom-Jun Kim, Tanmayi D. Vashist, Anh Minh Tran Huynh, Yongchao Dou, Xuxu Gou, Chen Huang, Zhiao Shi, Bo Wen, Viktoriya Korchina, Richard A. Gibbs, Donna M. Muzny, Harshavardhan Doddapaneni, Lacey E. Dobrolecki, Henry Rodriguez, Ana I. Robles, Tara Hiltke, Michael T. Lewis, Julie R. Nangia, Maryam Nemati Shafaee, Shunqiang Li, Ian S. Hagemann, Jeremy Hoog, Bora Lim, C. Kent Osborne, D.R. Mani, Michael A. Gillette, Bing Zhang, Gloria V. Echeverria, George Miles, Mothaffar F. Rimawi, Steven A. Carr, Foluso O. Ademuyiwa, Shankha Satpathy, Matthew J. Ellis
Publikováno v:
Cancer Discovery. 12:2586-2605
Microscaled proteogenomics was deployed to probe the molecular basis for differential response to neoadjuvant carboplatin and docetaxel combination chemotherapy for triple-negative breast cancer (TNBC). Proteomic analyses of pretreatment patient biop
Autor:
Matthew J. Ellis, Shankha Satpathy, Foluso O. Ademuyiwa, Steven A. Carr, Mothaffar F. Rimawi, George Miles, Gloria V. Echeverria, Bing Zhang, Michael A. Gillette, D.R. Mani, C. Kent Osborne, Bora Lim, Jeremy Hoog, Ian S. Hagemann, Shunqiang Li, Maryam Nemati Shafaee, Julie R. Nangia, Michael T. Lewis, Tara Hiltke, Ana I. Robles, Henry Rodriguez, Lacey E. Dobrolecki, Harshavardhan Doddapaneni, Donna M. Muzny, Richard A. Gibbs, Viktoriya Korchina, Bo Wen, Zhiao Shi, Chen Huang, Xuxu Gou, Yongchao Dou, Anh Minh Tran Huynh, Tanmayi D. Vashist, Beom-Jun Kim, Erik J. Bergstrom, Jonathan T. Lei, Karsten Krug, Eric J. Jaehnig, Meenakshi Anurag
Microscaled proteogenomics was deployed to probe the molecular basis for differential response to neoadjuvant carboplatin and docetaxel combination chemotherapy for triple-negative breast cancer (TNBC). Proteomic analyses of pretreatment patient biop
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2213f3db6710d869c1c4f3f803aa9523
https://doi.org/10.1158/2159-8290.c.6549759.v1
https://doi.org/10.1158/2159-8290.c.6549759.v1
Autor:
Matthew J. Ellis, Shankha Satpathy, Foluso O. Ademuyiwa, Steven A. Carr, Mothaffar F. Rimawi, George Miles, Gloria V. Echeverria, Bing Zhang, Michael A. Gillette, D.R. Mani, C. Kent Osborne, Bora Lim, Jeremy Hoog, Ian S. Hagemann, Shunqiang Li, Maryam Nemati Shafaee, Julie R. Nangia, Michael T. Lewis, Tara Hiltke, Ana I. Robles, Henry Rodriguez, Lacey E. Dobrolecki, Harshavardhan Doddapaneni, Donna M. Muzny, Richard A. Gibbs, Viktoriya Korchina, Bo Wen, Zhiao Shi, Chen Huang, Xuxu Gou, Yongchao Dou, Anh Minh Tran Huynh, Tanmayi D. Vashist, Beom-Jun Kim, Erik J. Bergstrom, Jonathan T. Lei, Karsten Krug, Eric J. Jaehnig, Meenakshi Anurag
Supplementary Figure from Proteogenomic Markers of Chemotherapy Resistance and Response in Triple-Negative Breast Cancer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5cddd49408408cb8699c178559bdada3
https://doi.org/10.1158/2159-8290.22541898
https://doi.org/10.1158/2159-8290.22541898
Autor:
Matthew J. Ellis, Shankha Satpathy, Foluso O. Ademuyiwa, Steven A. Carr, Mothaffar F. Rimawi, George Miles, Gloria V. Echeverria, Bing Zhang, Michael A. Gillette, D.R. Mani, C. Kent Osborne, Bora Lim, Jeremy Hoog, Ian S. Hagemann, Shunqiang Li, Maryam Nemati Shafaee, Julie R. Nangia, Michael T. Lewis, Tara Hiltke, Ana I. Robles, Henry Rodriguez, Lacey E. Dobrolecki, Harshavardhan Doddapaneni, Donna M. Muzny, Richard A. Gibbs, Viktoriya Korchina, Bo Wen, Zhiao Shi, Chen Huang, Xuxu Gou, Yongchao Dou, Anh Minh Tran Huynh, Tanmayi D. Vashist, Beom-Jun Kim, Erik J. Bergstrom, Jonathan T. Lei, Karsten Krug, Eric J. Jaehnig, Meenakshi Anurag
Supplementary Table from Proteogenomic Markers of Chemotherapy Resistance and Response in Triple-Negative Breast Cancer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0aaa3ac19a23458641597347d9d61321
https://doi.org/10.1158/2159-8290.22541895
https://doi.org/10.1158/2159-8290.22541895
Autor:
Shankha Satpathy, Fernanda Martins Rodrigues, Li Ding, Humam Kadara, Chandra Goparaju, Steven A. Carr, Irena Lanc, Jeffrey P. Ward, Ignacio I. Wistuba, Siddhartha Devarakonda, Ashiq Masood, Robert S. Fulton, Harvey I. Pass, Richard K. Wilson, Lucinda Fulton, Ramaswamy Govindan, Kymberlie H. Pepin, Daniel Morgensztern, Yize Li, Michael A. Gillette, Saiama N. Waqar, Sumithra Sankararaman
Publikováno v:
J Clin Oncol
PURPOSE Approximately 10%-40% of patients with lung cancer report no history of tobacco smoking (never-smokers). We analyzed whole-exome and RNA-sequencing data of 160 tumor and normal lung adenocarcinoma (LUAD) samples from never-smokers to identify