Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Shanker Karunanithi"'
Autor:
Adekunle T. Bademosi, James Steeves, Shanker Karunanithi, Oressia H. Zalucki, Rachel S. Gormal, Shu Liu, Elsa Lauwers, Patrik Verstreken, Victor Anggono, Frederic A. Meunier, Bruno van Swinderen
Publikováno v:
Cell Reports, Vol 22, Iss 2, Pp 427-440 (2018)
Summary: Propofol is the most commonly used general anesthetic in humans. Our understanding of its mechanism of action has focused on its capacity to potentiate inhibitory systems in the brain. However, it is unknown whether other neural mechanisms a
Externí odkaz:
https://doaj.org/article/63392f39f6834fef94c3eb1372e16020
Autor:
Tong Wang, Sally Martin, Tam H. Nguyen, Callista B. Harper, Rachel S. Gormal, Ramon Martínez-Mármol, Shanker Karunanithi, Elizabeth J. Coulson, Nick R. Glass, Justin J. Cooper-White, Bruno van Swinderen, Frédéric A. Meunier
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-16 (2016)
Signalling endosomes are known to be essential for neuronal survival. Here the authors show that, in cultured hippocampal neurons and live Drosophilalarval motor neurons, neuronal activity increases the retrograde flux of signalling endosomes, and th
Externí odkaz:
https://doaj.org/article/be42e86f725a40bf81556fbeac83c206
Autor:
Tong Wang, Sally Martin, Tam H. Nguyen, Callista B. Harper, Rachel S. Gormal, Ramon Martínez-Mármol, Shanker Karunanithi, Elizabeth J. Coulson, Nick R. Glass, Justin J. Cooper-White, Bruno van Swinderen, Frédéric A. Meunier
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-1 (2016)
Nature Communications 7: Article number: 12976 doi: (2016); Published: 30 September 2016; Updated: 23 November 2016 In Fig. 3 of this Article, an image attribution was inadvertently omitted. The drawing of a Drosophila larva in Fig. 3a is reproduced
Externí odkaz:
https://doaj.org/article/630dbcd8152746cfa31d141ae271bd1e
Autor:
Juan Mena Gonzalez, Peter G. Noakes, Nickolas A. Lavidis, Yong Qi Lin, G. Lorenzo Odierna, Bruno van Swinderen, Shanker Karunanithi, Andrew J. Moorhouse, G. Gregory Neely, Hareesh Menon
Publikováno v:
J Neurosci
Within mammalian brain circuits, activity-dependent synaptic adaptations, such as synaptic scaling, stabilize neuronal activity in the face of perturbations. Stability afforded through synaptic scaling involves uniform scaling of quantal amplitudes a
Autor:
Leo Marin, Oressia Zalucki, Shanker Karunanithi, Nickolas A. Lavidis, Deniz Ertekin, Bruno van Swinderen, Harold L. Atwood, Drew Cylinder
Publikováno v:
eNeuro
Visual Abstract
Propofol is the most common general anesthetic used for surgery in humans, yet its complete mechanism of action remains elusive. In addition to potentiating inhibitory synapses in the brain, propofol also impairs excitatory neuro
Propofol is the most common general anesthetic used for surgery in humans, yet its complete mechanism of action remains elusive. In addition to potentiating inhibitory synapses in the brain, propofol also impairs excitatory neuro
Autor:
Victor Anggono, Shanker Karunanithi, Bruno van Swinderen, Oressia Zalucki, Benjamin Kottler, Michael Troup
Publikováno v:
Anesthesiology. 131(3)
Editor’s Perspective What We Already Know about This Topic What This Article Tells Us That Is New Background Mutations in the presynaptic protein syntaxin1A modulate general anesthetic effects in vitro and in vivo. Coexpression of a truncated synta
Autor:
Justin J. Cooper-White, Rachel S. Gormal, Frederic A. Meunier, Tong Wang, Nick R. Glass, Elizabeth J. Coulson, Sally Martin, Bruno van Swinderen, Callista B. Harper, Tam H. Nguyen, Ramón Martínez-Mármol, Shanker Karunanithi
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-16 (2016)
ResearcherID
Nature Communications
ResearcherID
Nature Communications
Axonal retrograde transport of signalling endosomes from the nerve terminal to the soma underpins survival. As each signalling endosome carries a quantal amount of activated receptors, we hypothesized that it is the frequency of endosomes reaching th
Publikováno v:
Methods in enzymology. 602
Investigating mechanisms of general anesthesia requires access to multiple levels of neuronal function, from effects at individual synapses to responses in behaving animals. Drosophila melanogaster provides an excellent model to test different theori
Investigating mechanisms of general anesthesia requires access to multiple levels of neuronal function, from effects at individual synapses to responses in behaving animals. Drosophila melanogaster provides an excellent model to test different theori
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::54664ce660c5c2ee903100cbe8b6cfca
https://doi.org/10.1016/bs.mie.2018.02.003
https://doi.org/10.1016/bs.mie.2018.02.003
Autor:
Shu Liu, Shanker Karunanithi, Adekunle T. Bademosi, Oressia Zalucki, Elsa Lauwers, Rachel S. Gormal, Frederic A. Meunier, Victor Anggono, James Steeves, Patrik Verstreken, Bruno van Swinderen
Publikováno v:
Cell Reports
Cell Reports, Vol 22, Iss 2, Pp 427-440 (2018)
Cell Reports, Vol 22, Iss 2, Pp 427-440 (2018)
Summary: Propofol is the most commonly used general anesthetic in humans. Our understanding of its mechanism of action has focused on its capacity to potentiate inhibitory systems in the brain. However, it is unknown whether other neural mechanisms a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cb0f73f71e8c1d9500b7111416d05922
http://linkinghub.elsevier.com/retrieve/pii/S2211-1247(17)31878-8
http://linkinghub.elsevier.com/retrieve/pii/S2211-1247(17)31878-8