Zobrazeno 1 - 10
of 33
pro vyhledávání: '"Shankara, Anand"'
Autor:
Mark Bustoros, Shankara Anand, Romanos Sklavenitis-Pistofidis, Robert Redd, Eileen M. Boyle, Benny Zhitomirsky, Andrew J. Dunford, Yu-Tzu Tai, Selina J. Chavda, Cody Boehner, Carl Jannes Neuse, Mahshid Rahmat, Ankit Dutta, Tineke Casneuf, Raluca Verona, Efstathis Kastritis, Lorenzo Trippa, Chip Stewart, Brian A. Walker, Faith E. Davies, Meletios-Athanasios Dimopoulos, P. Leif Bergsagel, Kwee Yong, Gareth J. Morgan, François Aguet, Gad Getz, Irene M. Ghobrial
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-10 (2022)
Existing clinical models cannot fully capture smoldering multiple myeloma (SMM) heterogeneity. Here, integration of 42 genetic alterations from 214 SMM patients using an unsupervised binary matrix factorization clustering approach results in the iden
Externí odkaz:
https://doaj.org/article/078805a3b909435fb477a229095a08ed
Autor:
Amaro Taylor-Weiner, François Aguet, Nicholas J. Haradhvala, Sager Gosai, Shankara Anand, Jaegil Kim, Kristin Ardlie, Eliezer M. Van Allen, Gad Getz
Publikováno v:
Genome Biology, Vol 20, Iss 1, Pp 1-5 (2019)
Abstract Current genomics methods are designed to handle tens to thousands of samples but will need to scale to millions to match the pace of data and hypothesis generation in biomedical science. Here, we show that high efficiency at low cost can be
Externí odkaz:
https://doaj.org/article/dcf50f447bc54152a6b4da1e1ef12b31
Autor:
Benjamin L. Ebert, Siddhartha Jaiswal, Robert K. Bradley, Gad Getz, Chip Stewart, Elli Papaemmanuil, Luca Malcovati, Eva Hellstrom-Lindberg, Steven A. Carr, Kasper Lage, Donna S. Neuberg, Monkol Lek, Daniel G. MacArthur, Ruth Loos, Andrew D. Johnson, Michael H. Cho, Pinkal Desai, Bruce M. Psaty, Shankara Anand, Alex Barbera, Timothy Wood, Amaro Taylor-Weiner, Andrew Dunford, Abhishek Niroula, Mendy Miller, Joshua S. Weinstock, Alexander G. Bick, Björn Nilsson, Edyta Malolepsza, Benjamin Tanenbaum, Caroline Stanclift, Monica Schenone, Waihay Wong, Akansha Tarun, Marie McConkey, Cecilia A. Castellano, Anna Gallì, Maria Creignou, Gabriele Todisco, Emma R. Hoppe, Elsa Bernard, Matthew Leventhal, Ellen M. Beauchamp
Supplementary Tables S1-S19
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e51f56a5f32d341b5c2e51674ff765e
https://doi.org/10.1158/2643-3230.22543738
https://doi.org/10.1158/2643-3230.22543738
Autor:
Benjamin L. Ebert, Siddhartha Jaiswal, Robert K. Bradley, Gad Getz, Chip Stewart, Elli Papaemmanuil, Luca Malcovati, Eva Hellstrom-Lindberg, Steven A. Carr, Kasper Lage, Donna S. Neuberg, Monkol Lek, Daniel G. MacArthur, Ruth Loos, Andrew D. Johnson, Michael H. Cho, Pinkal Desai, Bruce M. Psaty, Shankara Anand, Alex Barbera, Timothy Wood, Amaro Taylor-Weiner, Andrew Dunford, Abhishek Niroula, Mendy Miller, Joshua S. Weinstock, Alexander G. Bick, Björn Nilsson, Edyta Malolepsza, Benjamin Tanenbaum, Caroline Stanclift, Monica Schenone, Waihay Wong, Akansha Tarun, Marie McConkey, Cecilia A. Castellano, Anna Gallì, Maria Creignou, Gabriele Todisco, Emma R. Hoppe, Elsa Bernard, Matthew Leventhal, Ellen M. Beauchamp
Clonal hematopoiesis results from somatic mutations in cancer driver genes in hematopoietic stem cells. We sought to identify novel drivers of clonal expansion using an unbiased analysis of sequencing data from 84,683 persons and identified common mu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::55289da636eb1db4ca374a11330f8d09
https://doi.org/10.1158/2643-3230.c.6550390
https://doi.org/10.1158/2643-3230.c.6550390
Autor:
Benjamin L. Ebert, Siddhartha Jaiswal, Robert K. Bradley, Gad Getz, Chip Stewart, Elli Papaemmanuil, Luca Malcovati, Eva Hellstrom-Lindberg, Steven A. Carr, Kasper Lage, Donna S. Neuberg, Monkol Lek, Daniel G. MacArthur, Ruth Loos, Andrew D. Johnson, Michael H. Cho, Pinkal Desai, Bruce M. Psaty, Shankara Anand, Alex Barbera, Timothy Wood, Amaro Taylor-Weiner, Andrew Dunford, Abhishek Niroula, Mendy Miller, Joshua S. Weinstock, Alexander G. Bick, Björn Nilsson, Edyta Malolepsza, Benjamin Tanenbaum, Caroline Stanclift, Monica Schenone, Waihay Wong, Akansha Tarun, Marie McConkey, Cecilia A. Castellano, Anna Gallì, Maria Creignou, Gabriele Todisco, Emma R. Hoppe, Elsa Bernard, Matthew Leventhal, Ellen M. Beauchamp
Supplementary Figures S1-S11
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::08370a390f5261d6d0398c3791fc3597
https://doi.org/10.1158/2643-3230.22543741.v1
https://doi.org/10.1158/2643-3230.22543741.v1
Autor:
Gad Getz, Se-Hoon Lee, Chan-Young Ock, Andrew D. Cherniack, Peter W. Laird, Justin F. Gainor, David I. Heiman, Jaegil Kim, Shankara Anand, Mendy Miller, Hongui Cha, Yifat Geffen, Whijae Roh
Lung adenocarcinoma (LUAD) is one of the most common cancer types and has various treatment options. Better biomarkers to predict therapeutic response are needed to guide choice of treatment modality and to improve precision medicine. Here, we used a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::11f1d45cc3eaa2a17575de2c2e07fb34
https://doi.org/10.1158/0008-5472.c.6514175
https://doi.org/10.1158/0008-5472.c.6514175
Autor:
Gad Getz, Se-Hoon Lee, Chan-Young Ock, Andrew D. Cherniack, Peter W. Laird, Justin F. Gainor, David I. Heiman, Jaegil Kim, Shankara Anand, Mendy Miller, Hongui Cha, Yifat Geffen, Whijae Roh
Supplementary Figure from High-Resolution Profiling of Lung Adenocarcinoma Identifies Expression Subtypes with Specific Biomarkers and Clinically Relevant Vulnerabilities
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::11380696dbf1b401c9bef968af362e3b
https://doi.org/10.1158/0008-5472.22432583
https://doi.org/10.1158/0008-5472.22432583
Autor:
Gad Getz, Se-Hoon Lee, Chan-Young Ock, Andrew D. Cherniack, Peter W. Laird, Justin F. Gainor, David I. Heiman, Jaegil Kim, Shankara Anand, Mendy Miller, Hongui Cha, Yifat Geffen, Whijae Roh
Supplementary Data from High-Resolution Profiling of Lung Adenocarcinoma Identifies Expression Subtypes with Specific Biomarkers and Clinically Relevant Vulnerabilities
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::157ef2d7c49c20273273e7e67df67570
https://doi.org/10.1158/0008-5472.22432598
https://doi.org/10.1158/0008-5472.22432598
Autor:
Gad Getz, Se-Hoon Lee, Chan-Young Ock, Andrew D. Cherniack, Peter W. Laird, Justin F. Gainor, David I. Heiman, Jaegil Kim, Shankara Anand, Mendy Miller, Hongui Cha, Yifat Geffen, Whijae Roh
Supplementary Table from High-Resolution Profiling of Lung Adenocarcinoma Identifies Expression Subtypes with Specific Biomarkers and Clinically Relevant Vulnerabilities
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::00ff39a24b5d2fd1e5f608871b0f5bba
https://doi.org/10.1158/0008-5472.22432565.v1
https://doi.org/10.1158/0008-5472.22432565.v1
Autor:
Kirsten Kubler, Agostina Nardone, Shankara Anand, Daniel Gorvich, Marjolein Droog, Francisco Hermida-Prado, Tara Akshi, Avery S Feit, Gabriella Cohen, Gwen Dackus, Matthew Pun, Yanan Kuang, Justin Cha, Mendy Miller, William J Gibson, Cloud P Paweletz, Eliezer M Van Allen, Flora E van Leeuwen, Petra Nederlof, Harry Hollema, Quang-Dé Nguyen, Marian JE Mourits, Ignaty Leshchiner, Chip Stewart, Ursula A Matulonis, Wilbert Zwart, Yosef E Maruvka, Gad Getz, Rinath Jeselsohn
Publikováno v:
Cancer Research. 82:GS2-09
Tamoxifen is widely used in the adjuvant treatment of estrogen receptor–positive (ER+) breast cancer and is an important drug for pre-menopausal women and post-menopausal patients who cannot tolerate aromatase inhibitors. Despite the clear clinical
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6c533d1be37ca1b1d6a88816bc753271
https://doi.org/10.1158/1538-7445.sabcs21-gs2-09
https://doi.org/10.1158/1538-7445.sabcs21-gs2-09