Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Shankar Venkatraman"'
Autor:
Guisheng Li, Zhulin Tan, Yibo Xu, Kanwar P. S. Sidhu, Bo Qu, Melissa A. Herbage, Magnus C. Eriksson, Xingzhong Zeng, Carl A. Busacca, Jean-Nicolas Desrosiers, Thomas Hampel, Oliver Niemeier, Carsten Reichel, Mai Thi Quynh Dang, Marvin Schoerer, Dirk Kemmer, Melanie Eick, Holger Werle, Soojin Kim, Zhibin Li, Shankar Venkatraman, Lanqi Jia, David A. Claremon, Klaus Fuchs, Niklas Heine, Denis Byrne, Bikshandarkoil Narayanan, Max Sarvestani, Joe Johnson, Ajith Premasiri, Larry J. Nummy, Jon C. Lorenz, Nizar Haddad, Nina C. Gonnella, Scott Pennino, Mariusz Krawiec, Chris H. Senanayake, Frederic Buono, Heewon Lee, Azad Hossain, Jinhua J. Song, Jonathan T. Reeves
Publikováno v:
Organic Process Research & Development. 26:3345-3372
Publikováno v:
SSRN Electronic Journal.
Socially Responsible investing has become a key point of discussion within the past few years as society gravitates towards producing positive externalities. The topic remains greatly contested especially when considering the perspectives of Milton F
Black-Litterman Framework to Test the Effectiveness of Technical Indicators in Portfolio Optimization
Publikováno v:
SSRN Electronic Journal.
This project explored the Black-Litterman framework to construct a portfolio of stocks listed in the S&P 100 index, and tracked the performance of the efficient portfolio against the S&P 100 index. Thirteen technical indicators (viz. RSI, Bollinger B
Publikováno v:
SSRN Electronic Journal.
A portfolio of commodity index-ETF pairs was constructed and its performance was compared against the Bloomberg commodity index. The portfolio was trained on data from 2011 to 2014 to determine the optimal parameters for trade-execution thresholds. U
Autor:
Suresh B. Singh, Shankar Venkatraman, Ya-Jun Zheng, Brian M. McKeever, Jing Yuan, Lawrence W. Dillard
Publikováno v:
Journal of Medicinal Chemistry. 56:4156-4180
The amyloid hypothesis asserts that excess production or reduced clearance of the amyloid-β (Aβ) peptides in the brain initiates a sequence of events that ultimately lead to Alzheimer's disease and dementia. The Aβ hypothesis has identified BACE1
Publikováno v:
Burger's Medicinal Chemistry and Drug Discovery. :447-828
Autor:
Salony Maniar, Russell B. Lingham, Benito Munoz, Michael F. Gardner, Kenneth Alves, Alec D. Lebsack, Shankar Venkatraman, Joyce K. James, Qian Si, Bowei Wang, Richard A. Mumford, Nicholas Stock, Kelly M. Treonze, Jasmine Zunic
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 19:5803-5806
A series of prolyl-N-isonicotinoyl-(L)-4-aminophenylalanine derivatives substituted at the proline 4-position with cyclic amines was evaluated as VLA-4 antagonists. The ring size and presence or absence of fluorine affected potency and receptor occup
Autor:
Lawrence W. Dillard, Margit Bauer, Lamont Howard, Achim Sauer, Barbara A. Kruk, Scott Hobson, Angel Morales-Ramos, Yi Zhao, Shankar Venkatraman, Klaus Fuchs, Yuri Bukhtiyarov, Cornelia Dorner-Ciossek, Deepak S. Lala
Publikováno v:
Alzheimer's & Dementia. 11
Autor:
Gregg Wesolowski, James T. Palmer, Walter Yu, Eduardo L. Setti, Harry Cheung, Shankar Venkatraman, Joel Robichaud, Xiaoming Xie
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 16:4296-4299
The synthesis and biological profile of a novel series of potent and selective inhibitors of cysteine protease cathepsin K (Cat K) are described. Pharmacokinetic evaluation of 12 indicated that some members of this series could be suitable candidates
Autor:
Peppi Prasit, James T. Palmer, Robert G. Strickley, M. David Percival, Liang Liu, Dan-Xiong Wang, Rohan Mendonca, Donald B. Kimmel, Leland C. Ii Burrill, Oballa Renata Marcella, Denis Riendeau, Colena Johnson, Tobee Chung, Young Robert N, Mary E. McGrath, John McCarter, Gregg Wesolowski, Michael C. Venuti, Eric B. Springman, Sevgi B. Rodan, Robert M. Rydzewski, James W. Janc, Bryant Clifford M, Z. Walter Yu, Harry Cheung, Eduardo L. Setti, Tian Zong-Qiang, Dana E. Davis, Jean-Pierre Falgueyret, Philip Enriquez, John R. Somoza, Gideon A. Rodan, Shankar Venkatraman
Publikováno v:
Journal of Medicinal Chemistry. 48:7520-7534
We have prepared a series of achiral aminoacetonitriles, bearing tri-ring benzamide moieties and an aminocyclohexanecarboxylate residue at P2. This combination of binding elements resulted in sub-250 pM, reversible, selective, and orally bioavailable