Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Shankar Revu"'
Autor:
Shankar Revu, Jing Wu, Matthew Henkel, Natalie Rittenhouse, Ashley Menk, Greg M. Delgoffe, Amanda C. Poholek, Mandy J. McGeachy
Publikováno v:
Cell Reports, Vol 22, Iss 10, Pp 2642-2653 (2018)
Summary: Th17 cells drive autoimmune disease but also control commensal microbes. A common link among antigens from self-proteins or commensal microbiota is relatively low activation of T cell receptor (TCR) and costimulation signaling. Indeed, stron
Externí odkaz:
https://doaj.org/article/ccc4f882024b4e13883ca1100600cc92
Autor:
Shankar Revu, Lawrence P. Kane, Mandy J. McGeachy, Itay Raphael, Catherine H. Poholek, William F. Hawse, Gerard Hernandez-Mir, Lyndsay Avery
Publikováno v:
J Immunol
β-site amyloid precursor protein-cleaving enzyme 1 (BACE1) is best known for its role in Alzheimer's disease amyloid plaque formation but also contributes to neurodegenerative processes triggered by CNS injury. In this article, we report that BACE1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6a173d3495a15b65229eba25409d2870
https://doi.org/10.4049/jimmunol.1800363
https://doi.org/10.4049/jimmunol.1800363
IL-17 metabolically reprograms activated fibroblastic reticular cells for proliferation and survival
Autor:
Natalie Rittenhouse, Shankar Revu, Saikat Majumder, Fang Du, Sarah L. Gaffen, Ashley V. Menk, Ulrich Siebenlist, Timothy W. Hand, Chetan V. Jawale, Dongwen Wu, Mandy J. McGeachy, Itay Raphael, Nilesh Amatya, Amanda C. Poholek, Greg M. Delgoffe, Saran Kupul, Partha S. Biswas, Amrita Bhattacharjee
Publikováno v:
Nature Immunology. 20:534-545
Lymph-node (LN) stromal cell populations expand during the inflammation that accompanies T cell activation. Interleukin-17 (IL-17)-producing helper T cells (TH17 cells) promote inflammation through the induction of cytokines and chemokines in periphe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e12007f060c12a3360c009eb2df49332
https://doi.org/10.1038/s41590-019-0367-4
https://doi.org/10.1038/s41590-019-0367-4
Publikováno v:
Racing for the Surface ISBN: 9783030344702
Orthopedic implants are medical devices surgically placed into the body to replace a missing joint or bone or to reinforce a damaged structure. However, there is up to a 28% loosening rate on cementless implanted knee joint prostheses within a 4–10
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::95bbc7903a632fb63fb135ad73ddd6b0
https://doi.org/10.1007/978-3-030-34471-9_3
https://doi.org/10.1007/978-3-030-34471-9_3
Autor:
Greg M. Delgoffe, Amanda C. Poholek, Ashley V. Menk, Natalie Rittenhouse, Shankar Revu, Matthew Henkel, Mandy J. McGeachy, Jing Wu
Publikováno v:
Cell Reports, Vol 22, Iss 10, Pp 2642-2653 (2018)
Summary: Th17 cells drive autoimmune disease but also control commensal microbes. A common link among antigens from self-proteins or commensal microbiota is relatively low activation of T cell receptor (TCR) and costimulation signaling. Indeed, stron
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::146d724cd40051de81b4d2307137a607
https://doi.org/10.1016/j.celrep.2018.02.044
https://doi.org/10.1016/j.celrep.2018.02.044
Autor:
Uzodinma Uche, Natalie Rittenhouse, Mandy J. McGeachy, Itay Raphael, Lawrence P. Kane, Amanda C. Poholek, Saikat Majumder, Shankar Revu, Catherine H. Poholek, Dongwen Wu
Publikováno v:
The Journal of Experimental Medicine
STAT3 transcription factor activity is critical for Th17 cell development. Poholek et al. report that STAT3 maintains proliferation and function of autoimmune effector Th17 cells by limiting STAT1 activation and sustaining mitochondrial membrane pote
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ac83e4599b39da6ec3555f79b557f305
https://pubmed.ncbi.nlm.nih.gov/32697822
https://pubmed.ncbi.nlm.nih.gov/32697822
IL-17 metabolically reprograms activated fibroblastic reticular cells for proliferation and survival
Autor:
Saikat, Majumder, Nilesh, Amatya, Shankar, Revu, Chetan V, Jawale, Dongwen, Wu, Natalie, Rittenhouse, Ashley, Menk, Saran, Kupul, Fang, Du, Itay, Raphael, Amrita, Bhattacharjee, Ulrich, Siebenlist, Timothy W, Hand, Greg M, Delgoffe, Amanda C, Poholek, Sarah L, Gaffen, Partha S, Biswas, Mandy J, McGeachy
Publikováno v:
Nature immunology. 20(5)
Lymph-node (LN) stromal cell populations expand during the inflammation that accompanies T cell activation. Interleukin-17 (IL-17)-producing helper T cells (T
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::bf5b36dec8d4668a55ed9d9bf96d96bc
https://pubmed.ncbi.nlm.nih.gov/30971770
https://pubmed.ncbi.nlm.nih.gov/30971770
Autor:
Mandy J. McGeachy, Shankar Revu, Jing Wu, Natalie Rittenhouse, Ashley Menk, Greg M. Delgoffe, Amanda C. Poholek
Publikováno v:
The Journal of Immunology. 200:164.1-164.1
Th17 cells drive autoimmune disease but also control commensal microbes. A common link between antigens from self-proteins or commensal microbiota is relatively low activation of T cell receptor and costimulation signaling. Indeed, strong TCR/CD28 st
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::84f8db5c80979be7ed6af2d6feabe054
https://doi.org/10.4049/jimmunol.200.supp.164.1
https://doi.org/10.4049/jimmunol.200.supp.164.1
Autor:
Michael Hummel, Thottala Jayaraman, Eduardo E. Castilla, Juan C. Mereb, Dana T. Brožková, Timothy D. Ruff, Alexandre R. Vieira, José Mauro Granjeiro, Jessica Briseño-Ruiz, Hong Yuan Hsin, Mary L. Marazita, Jessalyn Forella, Marcelo de Castro Costa, Leonardo Santos Antunes, Shankar Revu, Merve Bayram, Regina C. Sencak, Erika Calvano Küchler, Megan L. Weber, Kathleen Deeley, Lívia Azeredo Alves Antunes, Vanessa M. Trombetta, Fernando A. Poletta, Hongjiao Ouyang, Patricia Nivoloni Tannure, Fernanda Volpe de Abreu, Iêda M. Orioli, Figen Seymen, Mine Koruyucu, Ersan Kalay, Takehiko Shimizu, Asli Patir
Publikováno v:
BMC Medical Genetics
CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
BACKGROUND: Congenital forms of hearing impairment can be caused by mutations in the estrogen related receptor beta (ESRRB) gene. Our initial linkage studies suggested the ESRRB locus is linked to high caries experience in humans. METHODS: We tested
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a0d2c17be063fc9b616f490f9490db1
https://pubmed.ncbi.nlm.nih.gov/25023176
https://pubmed.ncbi.nlm.nih.gov/25023176
Autor:
Petra Neregård, Anca I. Catrina, Shankar Revu, af Klint E, Marianne Engström, Akilan Krishnamurthy
Publikováno v:
Scandinavian Journal of Rheumatology; Vol 43
Etanercept is an effective tumour necrosis factor (TNF)-α inhibitor drug with the unique ability to block not only TNF-α but also lymphotoxin (LT)-α, at least in vitro. We aimed to investigate the in vivo effect of etanercept on synovial expressio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d64d09befdad6b5f81fb18178e82856
https://pubmed.ncbi.nlm.nih.gov/24313444
https://pubmed.ncbi.nlm.nih.gov/24313444