Výsledky vyhledávání - "Shankar K. Nayak"

Cancer Vaccine Potency: Is There a Dose/Response Relationship for Patient-Specific Vaccines and Clinical Outcomes?

Autor: Robert O. Dillman, Linda D. Beutel, Shankar K. Nayak, Carol DePriest, Senthamil R. Selvan, Patric M. Schiltz

Publikováno v: Cancer Biotherapy and Radiopharmaceuticals. 20:373-378

Determination of potency is a challenging problem for patient-specific products derived from autologous cells. For several years, we have been investigating the safety and therapeutic potential of patient- specific vaccines derived from short-term au

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3464a50440f496f9bc0bf6a83de917ca
https://doi.org/10.1089/cbr.2005.20.373

Zobrazit plný text záznamu

Autologous Tumor Cell Line–Derived Vaccine for Patient-Specific Treatment of Advanced Renal Cell Carcinoma

Autor: Linda D. Beutel, Louis A. VanderMolen, Robert O. Dillman, Cristina de Leon, Carol DePriest, Neil M. Barth, Khosrow Mahdavi, Shankar K. Nayak

Publikováno v: Cancer Biotherapy and Radiopharmaceuticals. 19:570-580

We previously reported the laboratory methodology for producing patient-specific irradiated autologous tumor-cell products derived from short-term cultured tumor cells from resected renal cell carcinoma, and described preliminary clinical results. In

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::54116ca724f0fac38b5ffaf985b08981
https://doi.org/10.1089/cbr.2004.19.570

Zobrazit plný text záznamu

Phase I/II Trial of Autologous Tumor Cell Line–Derived Vaccines for Recurrent or Metastatic Sarcomas

Autor: Cheryl Peterson, Linda D. Beutel, Shankar K. Nayak, Senthamil R. Selvan, Robert O. Dillman, Neil M. Barth, Cristina de Leon, Carol DePriest

Publikováno v: Cancer Biotherapy and Radiopharmaceuticals. 19:581-588

We previously reported the laboratory methodology for producing patient-specific irradiated autologous tumor-cell products derived from short-term cultured tumor cells. We attempted to determine the feasibility, safety, and clinical effects of autolo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d9dd9d4ddc8886b91ed164cdadb44a0
https://doi.org/10.1089/cbr.2004.19.581

Zobrazit plný text záznamu

Interferon-Gamma or Granulocyte-Macrophage Colony-Stimulating Factor Administered as Adjuvants With a Vaccine of Irradiated Autologous Tumor Cells From Short-Term Cell Line Cultures: A Randomized Phase 2 Trial of the Cancer Biotherapy Research Group

Autor: Carol DePriest, Robert O. Dillman, Michael C. Wiemann, Shankar K. Nayak, C DeLeon, K Hood

Publikováno v: Journal of Immunotherapy. 26:367-373

The objective was to study the effects of patient-specific vaccine immunotherapy administered with either interferon-gamma (IFNgamma) or granulocyte-macrophage colony stimulating factor (GM-CSF) in patients with metastatic cancer. Short-term cell lin

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::33ba6863c8fef3277123d193f732163e
https://doi.org/10.1097/00002371-200307000-00009

Zobrazit plný text záznamu

Irradiated Cells from Autologous Tumor Cell Lines as Patient-Specific Vaccine Therapy in 125 Patients with Metastatic Cancer: Induction of Delayed-Type Hypersensitivity to Autologous Tumor is Associated with Improved Survival

Autor: Linda D. Beutel, Robert O. Dillman, Shankar K. Nayak, Audrey A. O'Connor, Neil M. Barth, B. S. N. Carol Depriest, Cristina de Leon

Publikováno v: Cancer Biotherapy and Radiopharmaceuticals. 17:51-66

We established short-term cultures of pure tumor cells for use as autologous tumor cell vaccines in an effort to study the effects of patients-specific immunotherapy.Surgically resected fresh tumor was obtained from patients with metastatic cancer. S

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aea22b71a0cb8cb560e1f2bbd8cb7c08
https://doi.org/10.1089/10849780252824073

Zobrazit plný text záznamu

Short-Term Tumor Cell Lines from Breast Cancer for Use as Autologous Tumor Cell Vaccines in the Treatment of Breast Cancer

Autor: Shankar K. Nayak, Linda D. Beutel, Robert O. Dillman, Cristina de Leon

Publikováno v: Cancer Biotherapy and Radiopharmaceuticals. 16:205-211

We tried to establish short-term cultures of autologous tumors from patients with breast carcinoma for potential use as active specific immunotherapy (i.e., autologous vaccine) after resection of primary breast cancer, and/or for the treatment of met

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1315723cedf03c24ddf4176bc0c0c8c9
https://doi.org/10.1089/10849780152389393

Zobrazit plný text záznamu

Treatment of Kidney Cancer with Autologous Tumor Cell Vaccines of Short-Term Cell Lines Derived from Renal Cell Carcinoma

Autor: Louis A. VanderMolen, Audrey A. O'Connor, Robert O. Dillman, Neil M. Barth, David H. Garfield, Shankar K. Nayak, Khosrow Mahdavi, Cristina de Leon

Publikováno v: Cancer Biotherapy and Radiopharmaceuticals. 16:47-54

We established short-term cultures of autologous tumors from patients with renal carcinoma for use as active specific immunotherapy (i.e., autologous vaccine).Between 9/91 and 9/99 the cell biology laboratory of the Hoag Cancer Center received 69 kid

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::100ddcb3517e0eb4196b38ff65a7c885
https://doi.org/10.1089/108497801750096023

Zobrazit plný text záznamu

Short-Term Tumor Cell Lines from Renal Cell Carcinoma for Use as Autologous Tumor Cell Vaccines in the Treatment of Kidney Cancer

Autor: Robert O. Dillman, Linda D. Beutel, Shankar K. Nayak, Andrew N. Cornforth

Publikováno v: Cancer Biotherapy and Radiopharmaceuticals. 15:161-168

We have tried to establish short-term cultures of autologous tumors from patients with renal cell carcinoma that could be used as active specific immunotherapy (i.e., autologous vaccine) in such patients after resection of primary kidney cancer, and/

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c53ecddf8a08ba9c3537b09d2fe2141
https://doi.org/10.1089/cbr.2000.15.161

Zobrazit plný text záznamu

Tumor Localization by Tumor Infiltrating Lymphocytes Labeled with Indium-111 in Patients With Metastatic Renal Cell Carcinoma, Melanoma, and Colorectal Cancer

Autor: Linda D. Beutel, Neil M. Barth, Shankar K. Nayak, Audrey A. O'Connor, Robert O. Dillman, Patric M. Schiltz, S. Robert Hurwitz

Publikováno v: Cancer Biotherapy and Radiopharmaceuticals. 12:65-71

Adoptive immunotherapy with autologous tumor infiltrating lymphocytes (TIL) is a promising approach for cancer bio-therapy. One issue, however, is whether such cells actually migrate to sites of tumor after intravenous infusion. There have been sever

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9881efd2105237476ab29cffd9a1e878
https://doi.org/10.1089/cbr.1997.12.65

Zobrazit plný text záznamu

Establishing In Vitro Cultures of Autologous Tumor Cells for Use in Active Specific Immunotherapy

Autor: Shankar K. Nayak, Robert O. Dillman, Linda D. Beutel

Publikováno v: Journal of Immunotherapy. 14:65-69

For active specific immunotherapy, autologous tumor cells grown in vitro may be a more appropriate source of tumor antigen than allogeneic tumor cell lines, autologous tumor cell suspensions, or purified/synthetic tumor antigen. A major limitation to

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ec9952e0fc331dbb76d97bd5c1b8fdcc
https://doi.org/10.1097/00002371-199307000-00009

Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání