Zobrazeno 1 - 10
of 384
pro vyhledávání: '"Shankar, Balasubramanian"'
Autor:
Sean M. Flynn, Somdutta Dhir, Krzysztof Herka, Colm Doyle, Larry Melidis, Angela Simeone, Winnie W. I. Hui, Rafael de Cesaris Araujo Tavares, Stefan Schoenfelder, David Tannahill, Shankar Balasubramanian
Publikováno v:
Genome Biology, Vol 25, Iss 1, Pp 1-10 (2024)
Abstract Methods to measure chromatin contacts at genomic regions bound by histone modifications or proteins are important tools to investigate chromatin organization. However, such methods do not capture the possible involvement of other epigenomic
Externí odkaz:
https://doaj.org/article/64f8f18f52c349d5bcf820beb8d79a27
Publikováno v:
Quantum, Vol 8, p 1448 (2024)
We propose a new model of quantum computation comprised of low-weight measurement sequences that simultaneously encode logical information, enable error correction, and apply logical gates. These measurement sequences constitute a new class of quantu
Externí odkaz:
https://doaj.org/article/cff6b228475441afb3891963b18daefd
Autor:
Xiaohan Qu, Zhen Lin, Janarthanan Jayawickramarajah, John S. Alsager, Emily Schmidt, Kenneth P. Nephew, Fang Fang, Shankar Balasubramanian, Bin Shan
Publikováno v:
iScience, Vol 26, Iss 12, Pp 108559- (2023)
Summary: The cancer-promoting lncRNA HOTAIR has multiple isoforms. Which isoform of HOTAIR accounts for its expression and functions in cancer is unknown. Unlike HOTAIR’s canonical intergenic isoform NR_003716 (HOTAIR-C), the novel isoform NR_04751
Externí odkaz:
https://doaj.org/article/fe73e8f106554b4b99f7ce44e4de26b0
Autor:
Katherine G. Zyner, Angela Simeone, Sean M. Flynn, Colm Doyle, Giovanni Marsico, Santosh Adhikari, Guillem Portella, David Tannahill, Shankar Balasubramanian
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-17 (2022)
Whether G-quadruplexes (G4s) regulate stem cell self-renewal and fate determination during embryonic development is not well understood. Here, the authors reveal that the embryonic stem cell state is defined by very high G4 abundance. G4s are progres
Externí odkaz:
https://doaj.org/article/23f994531a2a400ebdc8f744da78d2b7
Autor:
Shivanshu Misra, Shankar Balasubramanian, B Srikanth, Saravana Kumar, S Christinajoice, Deepa Nandhini, P Praveen Raj
Publikováno v:
Journal of Minimal Access Surgery, Vol 18, Iss 1, Pp 97-104 (2022)
Context: The importance of upper gastrointestinal (UGI) contrast study following sleeve gastrectomy (SG) is equivocal. It can, however, yield anatomical and functional details, the significance of which mostly remains unknown. Settings and Design: Th
Externí odkaz:
https://doaj.org/article/33e3eedfdc50496d8c59633217047d78
Autor:
Winnie W. I. Hui, Angela Simeone, Katherine G. Zyner, David Tannahill, Shankar Balasubramanian
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-7 (2021)
Abstract G-quadruplexes (G4s) are four-stranded DNA secondary structures that form in guanine-rich regions of the genome. G4s have important roles in transcription and replication and have been implicated in genome instability and cancer. Thus far mo
Externí odkaz:
https://doaj.org/article/003e83e1b961406db41ad6a9bc1d03f5
Autor:
Dhaval Varshney, Sergio Martinez Cuesta, Barbara Herdy, Ummi Binti Abdullah, David Tannahill, Shankar Balasubramanian
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-11 (2021)
Abstract Four-stranded G-quadruplex (G4) structures form from guanine-rich tracts, but the extent of their formation in cellular RNA and details of their role in RNA biology remain poorly defined. Herein, we first delineate the presence of endogenous
Externí odkaz:
https://doaj.org/article/74c8d5eda01043c79eff0b1eba8756f2
Autor:
IC Navarro, Dalila Bensaddek, Kin Man Suen, Angus Lamond, Arun Tanpure, Eric A Miska, Shankar Balasubramanian
Publikováno v:
Wellcome Open Research, Vol 7 (2022)
Background: Methylation of carbon-5 of cytosines (m5C) is a conserved post-transcriptional nucleotide modification of RNA with widespread distribution across organisms. It can be further modified to yield 5-hydroxymethylcytidine (hm5C), 5-formylcytid
Externí odkaz:
https://doaj.org/article/7be7f37ee54c49e68426dbf39db16b70
Publikováno v:
Journal of High Energy Physics, Vol 2021, Iss 7, Pp 1-47 (2021)
Abstract Reflectionless potentials play an important role in constructing exact solutions to classical dynamical systems (such as the Korteweg-de Vries equation), non-perturbative solutions of various large-N field theories (such as the Gross-Neveu m
Externí odkaz:
https://doaj.org/article/e3c6e2bbe33d44629ee9375a26194c16
Autor:
Jiazhen Shen, Dhaval Varshney, Angela Simeone, Xiaoyun Zhang, Santosh Adhikari, David Tannahill, Shankar Balasubramanian
Publikováno v:
Genome Biology, Vol 22, Iss 1, Pp 1-14 (2021)
Abstract Background Four-stranded G-quadruplexes (G4s) are DNA secondary structures in the human genome that are primarily found in active promoters associated with elevated transcription. Here, we explore the relationship between the folding of prom
Externí odkaz:
https://doaj.org/article/d4efa02a305743abbb6af4b97685632b