Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Shanique Young"'
Autor:
Joe Ryan Delaney, Chandni B. Patel, Katelyn McCabe Willis, Mina Haghighiabyaneh, Joshua Axelrod, Isabelle Tancioni, Dan Lu, Jaidev Bapat, Shanique Young, Octavia Cadassou, Alena Bartakova, Parthiv Sheth, Carley Haft, Sandra Hui, Cheryl Saenz, David D. Schlaepfer, Olivier Harismendy, Dwayne G. Stupack
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-11 (2017)
Cancers accumulate multiple single copy number alterations, but their impact is unclear. Here, the authors computationally demonstrate a disruption of genes associated with autophagy in ovarian cancer, show impact on autophagic flux, and note the eff
Externí odkaz:
https://doaj.org/article/4693ab4669b34978ad4a226632a7b4a7
Autor:
Chandni Patel, Dan Lu, Joshua Axelrod, Katelyn McCabe Willis, Dwayne G. Stupack, Isabelle Tancioni, Sandra Hui, David D. Schlaepfer, Shanique Young, Octavia Cadassou, Parthiv Sheth, Carley Haft, Jaidev Bapat, Cheryl C. Saenz, Mina Haghighiabyaneh, Olivier Harismendy, Alena Bartakova, Joe R. Delaney
Publikováno v:
Nature Communications
Nature Communications, Vol 8, Iss 1, Pp 1-11 (2017)
Nature communications, vol 8, iss 1
Delaney, JR; Patel, CB; Willis, KM; Haghighiabyaneh, M; Axelrod, J; Tancioni, I; et al.(2017). Haploinsufficiency networks identify targetable patterns of allelic deficiency in low mutation ovarian cancer. NATURE COMMUNICATIONS, 8. doi: 10.1038/ncomms14423. UC San Diego: Retrieved from: http://www.escholarship.org/uc/item/5vp9070r
Nature Communications, Vol 8, Iss 1, Pp 1-11 (2017)
Nature communications, vol 8, iss 1
Delaney, JR; Patel, CB; Willis, KM; Haghighiabyaneh, M; Axelrod, J; Tancioni, I; et al.(2017). Haploinsufficiency networks identify targetable patterns of allelic deficiency in low mutation ovarian cancer. NATURE COMMUNICATIONS, 8. doi: 10.1038/ncomms14423. UC San Diego: Retrieved from: http://www.escholarship.org/uc/item/5vp9070r
Identification of specific oncogenic gene changes has enabled the modern generation of targeted cancer therapeutics. In high-grade serous ovarian cancer (OV), the bulk of genetic changes is not somatic point mutations, but rather somatic copy-number
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9f6f59052e1381187b497e2e9e6fa0f1
https://pubmed.ncbi.nlm.nih.gov/28198375
https://pubmed.ncbi.nlm.nih.gov/28198375
Autor:
Dwayne G. Stupack, Ainhoa Mielgo, Robert Yuan, Shanique Young, Jesse Liang, Michael C. Schmid
Publikováno v:
Apoptosis. 17:229-235
Caspase-8 can trigger cell death following prodomain-mediated recruitment to the 'death-inducing signaling complex.' The prodomain consists of two death effector domain (DED) motifs that undergo homotypic interactions within the cell. Aside from medi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2205d32e4511ef4e31f5128216ac2d76
https://doi.org/10.1007/s10495-011-0677-y
https://doi.org/10.1007/s10495-011-0677-y
Autor:
Catherine Yang, Jody D. Berry, Ella Mendoza, Janean Fisher, Dwayne G. Stupack, Shanique Young
Publikováno v:
Therapeutic Fc-Fusion Proteins
Therapeutic Fc-fusion proteins can be categorized loosely, based upon structural design, into two general classes. The first is the classical Fc fusion, whereby an extracellular domain (ECD) of a natural receptor is fused in-frame to the constant dom
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::558fc21001d55ca90da8c796e369f5a8
https://doi.org/10.1002/9783527675272.ch02
https://doi.org/10.1002/9783527675272.ch02
