Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Shanique C Smythe"'
Publikováno v:
JAIDS Journal of Acquired Immune Deficiency Syndromes. 55:161-169
Dapivirine, a nonnucleoside reverse transcriptase inhibitor, is in development as a microbicide for the protection of women against HIV infection. A randomized, double-blind, phase 1 trial was conducted in 36 healthy HIV-negative women to compare the
Autor:
Mark Mitchnick, Joseph Romano, Paul Coplan, Paulina E. Kaptur, Shanique C Smythe, Karen McCord, Annalene Nel
Publikováno v:
AIDS research and human retroviruses. 26(11)
To assess the pharmacokinetics of dapivirine in plasma and dapivirine concentrations in cervicovaginal fluids (CVF) and cervicovaginal tissues following vaginal administration of dapivirine microbicide gel in healthy, HIV-negative women for 10 days.
Autor:
Joseph Romano, Annalene Nel, Zeda F. Rosenberg, Shanique C Smythe, Karl Malcolm, Clare McCoy, Katherine Young
Publikováno v:
Journal of acquired immune deficiency syndromes (1999). 51(4)
Vaginal microbicides for the prevention of HIV transmission may be an important option for protecting women from infection. Incorporation of dapivirine, a lead candidate nonnucleoside reverse transcriptase inhibitor, into intravaginal rings (IVRs) fo
Autor:
Ireen Kiwelu, Gileard Masenga, Janneke van de Wijgert, Annalene Nel, Eveline Geubbels, Helen Rees, Claire von Mollendorf, Saidi Kapiga, Paul Coplan, Shanique C Smythe, Joseph Vyankandondera, Jocelyn Moyes
Publikováno v:
AIDS (London, England), 23(12), 1531-1538. Lippincott Williams and Wilkins
Objectives: To assess the local and systemic safety of dapivirine vaginal gel vs. placebo gel as well as the systemic absorption of dapivirine in healthy, HIV-negative women. Methods: Two prospective, randomized, double-blind, placebo-controlled phas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d652f36fe6710d0a1c978a938953f9b6
https://pure.amc.nl/en/publications/safety-tolerability-and-systemic-absorption-of-dapivirine-vaginal-microbicide-gel-in-healthy-hivnegative-women(5d7af859-bf2f-4e36-8d63-06dd38ce805f).html
https://pure.amc.nl/en/publications/safety-tolerability-and-systemic-absorption-of-dapivirine-vaginal-microbicide-gel-in-healthy-hivnegative-women(5d7af859-bf2f-4e36-8d63-06dd38ce805f).html
Autor:
Annalene M. Nel, Paul Coplan, Shanique C. Smythe, Karen McCord, Mark Mitchnick, Paulina E. Kaptur, Joseph Romano
Publikováno v:
AIDS Research & Human Retroviruses; Nov2010, Vol. 26 Issue 11, p1181-1190, 10p