Zobrazeno 1 - 10
of 36
pro vyhledávání: '"Shangeng Weng"'
Publikováno v:
Frontiers in Oncology, Vol 14 (2024)
ObjectiveThe aim of this study was to evaluate the prognostic potential of combining clinical features and radiomics with multiple machine learning (ML) algorithms in pancreatic ductal adenocarcinoma (PDAC).MethodsA total of 116 patients with PDAC wh
Externí odkaz:
https://doaj.org/article/c194906b858c4df08873057508d86890
A significant and persistent rise in the global burden of adolescent NAFLD and NASH estimated by BMI
Autor:
Xiao-Yun Lin, Jing-Mao Li, Ling-Yi Huang, Li-Yan Lin, Mei-Zhu Hong, Shangeng Weng, Jin-Shui Pan
Publikováno v:
Frontiers in Public Health, Vol 12 (2024)
BackgroundCurrently, there is a lack of global or even country/regional level data on adolescent non-alcoholic fatty liver disease (NAFLD) prevalence. However, an evidenced dose-dependent relationship exists between body mass index (BMI) and the risk
Externí odkaz:
https://doaj.org/article/5a4cad78c924415fad3280274a54f9bd
Publikováno v:
Frontiers in Oncology, Vol 14 (2024)
ObjectiveThe early recurrence of hepatocellular carcinoma (HCC) correlates with decreased overall survival. Microvascular invasion (MVI) stands out as a prominent hazard influencing post-resection survival status and metastasis in patients with HBV-r
Externí odkaz:
https://doaj.org/article/2d90b955127a42df97951e0fcf895508
Autor:
Yue Huang, Han Zhang, Lingfeng Chen, Qingzhu Ding, Dehua Chen, Guozhong Liu, Xiang Zhang, Qiang Huang, Denghan Zhang, Shangeng Weng
Publikováno v:
Frontiers in Oncology, Vol 14 (2024)
ObjectivesThis research aimed to assess the value of radiomics combined with multiple machine learning algorithms in the diagnosis of pancreatic ductal adenocarcinoma (PDAC) lymph node (LN) metastasis, which is expected to provide clinical treatment
Externí odkaz:
https://doaj.org/article/c6083bfb9ce940acaf88e88046ef46a4
Publikováno v:
Frontiers in Oncology, Vol 14 (2024)
ObjectiveTo construct and validate radiomics models for hepatocellular carcinoma (HCC) grade predictions based on contrast-enhanced CT (CECT).MethodsPatients with pathologically confirmed HCC after surgery and underwent CECT at our institution betwee
Externí odkaz:
https://doaj.org/article/c69a67653bee4664afc647cbf36b659e
Autor:
Chengjie Lin, Ting Li, Yan Wang, Shihui Lai, Yue Huang, Zhenyun Guo, Xiang Zhang, Shangeng Weng
Publikováno v:
Cell Death and Disease, Vol 14, Iss 3, Pp 1-11 (2023)
Abstract The aim of the present study was to clarify the mechanism of how METTL3 regulated pancreatic ductal adenocarcinoma (PDAC) progression by m6A modification of its downstream target mRNA and signaling pathway. Immunoblotting and qRT-PCR assays
Externí odkaz:
https://doaj.org/article/a61e8a6d7d7645faa4a6a19a0e03cd6f
Publikováno v:
Biology Direct, Vol 17, Iss 1, Pp 1-19 (2022)
Abstract Background Pancreatic cancer (PC) is highly malignant. Chemotherapy is the main treatment strategy, especially for patients with advanced PC. However, chemoresistance has always been a frequently encountered bottleneck. Hence, there is an ur
Externí odkaz:
https://doaj.org/article/86e1f71b518b4b99a9b6e25fb52dd94a
Autor:
Shihui Lai, Yan Wang, Ting Li, Yihong Dong, Yihao Lin, Liang Wang, Shangeng Weng, Xiang Zhang, Chengjie Lin
Publikováno v:
Cell & Bioscience, Vol 12, Iss 1, Pp 1-20 (2022)
Abstract Background Alternative splicing (AS) of genes has been found to affect gene stability, and its abnormal regulation can lead to tumorigenesis. CELF2 is a vital splicing factor to participate in mRNA alternative splicing. Its downregulation ha
Externí odkaz:
https://doaj.org/article/b646e201356c4ec391c3bc846c2f29ed
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-12 (2021)
Abstract To investigate the effect of duodenal-jejunal bypass (DJB) surgery on postoperative blood glucose in type 2 diabetic rats, and further explore possible mechanisms for the effect of surgical treatment of type 2 diabetes. Forty rats with type
Externí odkaz:
https://doaj.org/article/0f89dfa7057040d8a7c77fb7d0dc1cd0
Autor:
Zhenyun Guo, Xiang Zhang, Chengjie Lin, Yue Huang, Yun Zhong, Hailing Guo, Zhou Zheng, Shangeng Weng
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
Spermine synthase (SMS) is an enzyme participating in polyamine synthesis; however, its function and role in pancreatic cancer remains elusive. Here we report that SMS is upregulated in pancreatic cancer and predicts a worse overall survival and sign
Externí odkaz:
https://doaj.org/article/722c1cffc30d45f9b0908137d626c559