Zobrazeno 1 - 10
of 133
pro vyhledávání: '"Shang-zhong Xu"'
Autor:
Shang-Zhong Xu, Thozhukat Sathyapalan
Publikováno v:
Biomolecules, Vol 14, Iss 8, p 1032 (2024)
Cardiovascular diseases (CVDs) are the leading cause of death [...]
Externí odkaz:
https://doaj.org/article/deebb283ded74e259afca9c59c8989c1
Autor:
Hong-Ni Jiang, Bo Zeng, Yi Zhang, Nikoleta Daskoulidou, Hong Fan, Jie-Ming Qu, Shang-Zhong Xu
Publikováno v:
PLoS ONE, Vol 19, Iss 12, p e0315242 (2024)
[This corrects the article DOI: 10.1371/journal.pone.0067637.].
Externí odkaz:
https://doaj.org/article/ac2d2adaa51f4d599e98c06077ac2647
Autor:
Gui-Lan Chen, Bo Zeng, Hongni Jiang, Nikoleta Daskoulidou, Rahul Saurabh, Rumbidzai J. Chitando, Shang-Zhong Xu
Publikováno v:
Biomolecules, Vol 13, Iss 6, p 952 (2023)
An elevated level of circulating homocysteine (Hcy) has been regarded as an independent risk factor for cardiovascular disease; however, the clinical benefit of Hcy lowering-therapy is not satisfying. To explore potential unrevealed mechanisms, we in
Externí odkaz:
https://doaj.org/article/9fa36fe44b604655887cc5a0beb4faf4
Publikováno v:
Stem Cell Research & Therapy, Vol 11, Iss 1, Pp 1-11 (2020)
Abstract Background Bone mesenchymal stem cells (MSCs) can promote liver regeneration and inhibit inflammation and hepatic fibrosis. MSCs also can serve as a vehicle for gene therapy. Smad7 is an essential negative regulatory gene in the TGF-β1/Smad
Externí odkaz:
https://doaj.org/article/a3f997160ca04d32a676b788488cd6ca
Publikováno v:
PLoS ONE, Vol 16, Iss 2, p e0247234 (2021)
Elevated reactive oxygen species (ROS) in type 2 diabetes cause cellular damage in many organs. Recently, the new class of glucose-lowering agents, SGLT-2 inhibitors, have been shown to reduce the risk of developing diabetic complications; however, t
Externí odkaz:
https://doaj.org/article/85a3d9e368ef4bcd8f097f9b74fbd736
Autor:
Bo Zeng, Gui-Lan Chen, Eliana Garcia-Vaz, Sunil Bhandari, Nikoleta Daskoulidou, Lisa M. Berglund, Hongni Jiang, Thomas Hallett, Lu-Ping Zhou, Li Huang, Zi-Hao Xu, Viji Nair, Robert G. Nelson, Wenjun Ju, Matthias Kretzler, Stephen L. Atkin, Maria F. Gomez, Shang-Zhong Xu
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-12 (2017)
Patients with diabetic nephropathy suffer from impaired albumin reabsorption by proximal tubular epithelial cells. Here authors use diabetic and transgenic mouse models and in vitro models to show the cause for this lies in the down regulation and in
Externí odkaz:
https://doaj.org/article/d6d1cb0bcd8f49c9b88f64376cab64f6
Publikováno v:
Journal of Integrative Agriculture, Vol 15, Iss 6, Pp 1330-1337 (2016)
Omega-3 polyunsaturated fatty acids (ω-3 PUFAs) are essential components required for normal cellular function and have been shown to have important therapeutic and nutritional benefits in humans. But humans or mammals cannot naturally produce ω-3
Externí odkaz:
https://doaj.org/article/6b404d8a20f64f02a4cb800e7a22b60f
Publikováno v:
Journal of Integrative Agriculture, Vol 13, Iss 10, Pp 2253-2259 (2014)
This study investigated the effects of fermentation product containing phytase (FPP) that was fermented using waste vinegar residue (WVR) as substrate from Aspergillus ficuum NTG-23 on productive performance, egg quality, and phosphorus apparent meta
Externí odkaz:
https://doaj.org/article/fa9b59685789456881b14dbdfc331c55
Autor:
Hong-Ni Jiang, Bo Zeng, Yi Zhang, Nikoleta Daskoulidou, Hong Fan, Jie-Ming Qu, Shang-Zhong Xu
Publikováno v:
PLoS ONE, Vol 8, Iss 6, p e67637 (2013)
The canonical transient receptor potential (TRPC) channels are Ca(2+)-permeable cationic channels controlling the Ca(2+) influx evoked by G protein-coupled receptor activation and/or by Ca(2+) store depletion. Here we investigate the involvement of T
Externí odkaz:
https://doaj.org/article/6ed1cafe6c2143baaee33761a870845e
Autor:
Nawel Zaibi, Gui-Lan Chen, Thomas Hallett, Bo Zeng, Shang-Zhong Xu, Rahul Saurabh, Pengyun Li, Hussein N. Rubaiy
Publikováno v:
Br J Pharmacol
British Journal of Pharmacology
British Journal of Pharmacology
BACKGROUND AND PURPOSE: Mibefradil, a T‐type Ca(2+) channel blocker, has been investigated for treating solid tumours. However, its underlying mechanisms are still unclear. Here, we have investigated the pharmacological actions of mibefradil on Ora