Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Shang-Yin Chiang"'
Autor:
Pei-Rung Wu, Shang-Yin Chiang, Robert Midence, Wen-Chao Kao, Chun-Lun Lai, I-Cheng Cheng, Shen-Ju Chou, Chih-Cheng Chen, Chih-Yang Huang, Ruey-Hwa Chen
Publikováno v:
Cell Death and Disease, Vol 14, Iss 1, Pp 1-16 (2023)
Abstract Patients with mutations of WDR4, a substrate adaptor of the CUL4 E3 ligase complex, develop cerebellar atrophy and gait phenotypes. However, the underlying mechanisms remain unexplored. Here, we identify a crucial role of Wdr4 in cerebellar
Externí odkaz:
https://doaj.org/article/bcfab74854e6422e82765ba22f9778e9
Autor:
Hsin-Yi Chen, Shu-Jou Chan, Xinxin Liu, An-Chi Wei, Ru-In Jian, Kuan-Wei Huang, Yaw-Dong Lang, Jou-Ho Shih, Chun-Chieh Liao, Chiu-Lin Luan, Yu-Tung Kao, Shang-Yin Chiang, Pei-Wen Hsiao, Yuh-Shan Jou, Yunching Chen, Ruey-Hwa Chen
Publikováno v:
Journal of Hematology & Oncology, Vol 15, Iss 1, Pp 1-24 (2022)
Abstract Background Metastasis and chemoresistance are major culprits of cancer mortality, but factors contributing to these processes are incompletely understood. Methods Bioinformatics methods were used to identify the relations of Smyca expression
Externí odkaz:
https://doaj.org/article/a8ced82434e347259ea6f0bb87743738
Autor:
Shang-Yin Chiang, 江尚殷
103
In the ubiquitin-proteasome pathway, ubiquitin is conjugated to the target proteins by ubiquitin E3 ligases and removed by deubiquitinating enzymes (DUBs). Although a number of E3 ligases are known to play roles in neural development, little
In the ubiquitin-proteasome pathway, ubiquitin is conjugated to the target proteins by ubiquitin E3 ligases and removed by deubiquitinating enzymes (DUBs). Although a number of E3 ligases are known to play roles in neural development, little
Externí odkaz:
http://ndltd.ncl.edu.tw/handle/71353814603064694756
Autor:
Ruey-Hwa Chen, Shang Yin Chiang, Shen Ju Chou, Hung-Chih Kuo, Hsin Chieh Wu, Hsin Yi Chen, Chia Fang Wang, Nai Hsing Yeh, Shu-Yu Lin, Yi-Shuian Huang, Jou Ho Shih
Publikováno v:
Science Advances
Protein deubiquitination contributes to cortical development, and its dysregulation is linked to intellectual disability.
The role of protein stabilization in cortical development remains poorly understood. A recessive mutation in the USP11 gene
The role of protein stabilization in cortical development remains poorly understood. A recessive mutation in the USP11 gene
Autor:
Yulia V. Shulga, Tian-Min Fu, Shang Yin Chiang, Jonathan D. Lee, Jesse Katon, Suresh Jain, Lydia E. Matesic, Ruey-Hwa Chen, Chih-Hung Hsu, Shu-Yu Lin, Jacqueline Fung, Jinfang Zhang, Wenyi Wei, Yang Zhang, Chen Shen, Tomoki Ishikawa, Lixin Wan, Ming Chen, Julie Teruya-Feldstein, Hao Wu, Pier Paolo Pandolfi, John G. Clohessy, Assaf C. Bester, Emanuele Monteleone, Yu-Ru Lee, Hao Chen, Antonella Papa
Publikováno v:
Science. 364
Supporting tumor suppression The protein PTEN is a phosphatase and tumor suppressor whose activity is often decreased in human cancers. Thus, reactivating such a protein could potentially be an effective therapy against cancer. Lee et al. identified