Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Shang-Lin Chang"'
Autor:
Fu-Lung Yeh, Shang-Lin Chang, Golam Rizvee Ahmed, Hsin-I Liu, Luh Tung, Chung-Shu Yeh, Leah Stands Lanier, Corina Maeder, Che-Min Lin, Shu-Chun Tsai, Wan-Yi Hsiao, Wei-Hau Chang, Tien-Hsien Chang
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-9 (2021)
Yeast helicase Prp28 promotes the first step of spliceosome remodeling. By placing a photoactivatable unnatural amino acid in Prp28, the authors capture Prp28 in action revealing its dynamic interactions and cofactor Npl3.
Externí odkaz:
https://doaj.org/article/9e81c7d52d55433ab0c6e27d3c001065
Publikováno v:
PLoS Genetics, Vol 9, Iss 1, p e1003232 (2013)
Large-scale genome rearrangements have been observed in cells adapting to various selective conditions during laboratory evolution experiments. However, it remains unclear whether these types of mutations can be stably maintained in populations and h
Externí odkaz:
https://doaj.org/article/3493ed0f0ca54fb0a6ac7707f7b44ae9
Autor:
Shang-Lin Chang, Jun-Yi Leu
Publikováno v:
PLoS Genetics, Vol 7, Iss 3, p e1002034 (2011)
Various types of genetic modification and selective forces have been implicated in the process of adaptation to novel or adverse environments. However, the underlying molecular mechanisms are not well understood in most natural populations. Here we r
Externí odkaz:
https://doaj.org/article/705cd65ffeb348229bff488d33d6b195
Autor:
Shang-Lin Chang, 張尚麟
93
When Oreochromis mossambicus (tilapia) goes from a hypoosmotic (freshwater; FW) to a hyperosmotic (seawater, SW) environment, the osmolarity and the ionic concentrations of sodium and chloride ion in the Cerebral Spinal Fluid are raised. Howe
When Oreochromis mossambicus (tilapia) goes from a hypoosmotic (freshwater; FW) to a hyperosmotic (seawater, SW) environment, the osmolarity and the ionic concentrations of sodium and chloride ion in the Cerebral Spinal Fluid are raised. Howe
Externí odkaz:
http://ndltd.ncl.edu.tw/handle/23909276751551049952
Autor:
Che-Min Lin, Shu-Chun Tsai, Tien-Hsien Chang, Luh Tung, Hsin-I Liu, Wei-Hau Chang, Chung-Shu Yeh, Leah Stands Lanier, Golam Rizvee Ahmed, Corina Maeder, Fu-Lung Yeh, Wan-Yi Hsiao, Shang-Lin Chang
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-9 (2021)
Nature Communications
Nature Communications
Splicing, a key step in the eukaryotic gene-expression pathway, converts precursor messenger RNA (pre-mRNA) into mRNA by excising introns and ligating exons. This task is accomplished by the spliceosome, a macromolecular machine that must undergo seq
Publikováno v:
Nature Ecology & Evolution. 2:1818-1823
Essential genes form the core of a genome and are therefore thought to be indispensable for cellular viability. However, recent findings have challenged this notion in that cells may survive in the absence of some essential genes provided that releva
Autor:
Shang-Lin Chang, Jeffrey A. Pleiss, Jui-Hui Chen, Wei-Hau Chang, Chung-Shu Yeh, Chun-Hsiung Wang, Shih-Hsin Huang, Yue-Chang Chou, Tien-Hsien Chang, Amy Larson, Hsuan-Kai Wang
Publikováno v:
Nucleic Acids Research
Splicing is initiated by a productive interaction between the pre-mRNA and the U1 snRNP, in which a short RNA duplex is established between the 5′ splice site of a pre-mRNA and the 5′ end of the U1 snRNA. A long-standing puzzle has been why the A
Publikováno v:
Scientific Reports
Scientific Reports, Vol 9, Iss 1, Pp 1-9 (2019)
Scientific Reports, Vol 9, Iss 1, Pp 1-9 (2019)
Ciliates are unicellular eukaryotes known for their cellular complexity and wide range of natural habitats. How they adapt to their niches and what roles they play in ecology remain largely unknown. The genus Tetrahymena is among the best-studied gro
Publikováno v:
Nature ecologyevolution. 4(3)
Sex is common among eukaryotes, but entails considerable costs. The selective conditions that drive the evolutionary maintenance of sexual reproduction remain an open question. One long-standing explanation is that sex and recombination facilitate ad