Zobrazeno 1 - 10
of 165
pro vyhledávání: '"Shang-Der Chen"'
Autor:
Kai-Jung Lin, Shang-Der Chen, Kai-Lieh Lin, Chia-Wei Liou, Min-Yu Lan, Yao-Chung Chuang, Pei-Wen Wang, Jong-Jer Lee, Feng-Sheng Wang, Hung-Yu Lin, Tsu-Kung Lin
Publikováno v:
Cells, Vol 11, Iss 23, p 3829 (2022)
Parkinson disease (PD) is the second-most common neurodegenerative disease. The characteristic pathology of progressive dopaminergic neuronal loss in people with PD is associated with iron accumulation and is suggested to be driven in part by the nov
Externí odkaz:
https://doaj.org/article/e4d04c2af58b4fbdaec38e3da9af748b
Autor:
Kai-Lieh Lin, Shang-Der Chen, Kai-Jung Lin, Chia-Wei Liou, Yao-Chung Chuang, Pei-Wen Wang, Jiin-Haur Chuang, Tsu-Kung Lin
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
Cardiovascular diseases are one of the leading causes of death and global health problems worldwide. Multiple factors are known to affect the cardiovascular system from lifestyles, genes, underlying comorbidities, and age. Requiring high workload, me
Externí odkaz:
https://doaj.org/article/2b5f3de465f0446091156045b5020ba4
Autor:
Tsu-Kung Lin, Kai-Jung Lin, Kai-Lieh Lin, Chia-Wei Liou, Shang-Der Chen, Yao-Chung Chuang, Pei-Wen Wang, Jiin-Haur Chuang, Tzu-Jou Wang
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 8 (2020)
Parkinson's disease (PD) is a complex neurodegenerative disease with pathological hallmarks including progressive neuronal loss from the substantia nigra pars compacta and α-synuclein intraneuronal inclusions, known as Lewy bodies. Although the etio
Externí odkaz:
https://doaj.org/article/c8ffac486a2f4ab2ae251dd3f8af73a6
Publikováno v:
Redox Biology, Vol 16, Iss , Pp 263-275 (2018)
Stroke is the leading cause of adult disability and mortality in most developing and developed countries. The current best practices for patients with acute ischemic stroke include intravenous tissue plasminogen activator and endovascular thrombectom
Externí odkaz:
https://doaj.org/article/5818bae3581d4df3a9088301ad329d32
Autor:
Kai-Jung Lin, Tzu-Jou Wang, Shang-Der Chen, Kai-Lieh Lin, Chia-Wei Liou, Min-Yu Lan, Yao-Chung Chuang, Jiin-Haur Chuang, Pei-Wen Wang, Jong-Jer Lee, Feng-Sheng Wang, Hung-Yu Lin, Tsu-Kung Lin
Publikováno v:
Antioxidants, Vol 10, Iss 12, p 1935 (2021)
Parkinson’s disease (PD) is the second most common neurodegenerative disease after Alzheimer’s disease affecting more than 1% of the population over 65 years old. The etiology of the disease is unknown and there are only symptomatic managements a
Externí odkaz:
https://doaj.org/article/9cffad36f89c4cafbadb824f2c1e9cec
Autor:
Shang-Der Chen, Jenq-Lin Yang, Yi-Heng Hsieh, Tsu-Kung Lin, Yi-Chun Lin, A-Ching Chao, Ding-I Yang
Publikováno v:
Biomedicines, Vol 9, Iss 10, p 1308 (2021)
Alzheimer’s disease (AD) is the most common age-related neurodegenerative disease. It presents with progressive memory loss, worsens cognitive functions to the point of disability, and causes heavy socioeconomic burdens to patients, their families,
Externí odkaz:
https://doaj.org/article/1f1621e08b33413c8fa445e411e96ed5
Autor:
Chi-Ren Huang, Chih-Hsiang Lin, Shu-Chen Hsiao, Nai-Ching Chen, Wan-Chen Tsai, Shang-Der Chen, Yan-Ting Lu, Yao-Chung Chuang
Publikováno v:
Kaohsiung Journal of Medical Sciences, Vol 33, Iss 3, Pp 130-136 (2017)
Valproic acid (VPA) is a widely used antiepileptic drug (AED). When carbapenems are concomitantly used with VPA, the serum levels of VPA may decrease and aggravate seizures. The aim of this study was to evaluate the risk factors associated with decre
Externí odkaz:
https://doaj.org/article/37026a15f70848d0812c2c7326b1daff
Autor:
Tsu-Kung Lin, Yung-Yee Chang, Hung-Yu Lin, Chia-Wei Liou, Pei-Wen Wang, Jiin-Haur Chuang, Shang-Der Chen, Yao-Chung Chuang, Sheng-Teng Huang, Te-Yao Hsu, Cheng-Huei Peng, Min-Yu Lan
Publikováno v:
PLoS ONE, Vol 14, Iss 10, p e0224173 (2019)
Several inherited human diseases have been linked to mitochondrial aminoacyl-tRNA synthetases (mtARSs). Leukoencephalopathy with brainstem and spinal cord involvement and lactate elevation (LBSL) is a leukodystrophy caused by mutations in the DARS2 g
Externí odkaz:
https://doaj.org/article/273559d6f21f4cb3a0459a56e53033f9
Autor:
Jyun-Bin Huang, Nai-Ching Chen, Chien-Liang Chen, Mu-Hui Fu, Hsiu-Yung Pan, Chung-Yao Hsu, Shang-Der Chen, Yao-Chung Chuang
Publikováno v:
Journal of Clinical Medicine, Vol 10, Iss 1, p 61 (2020)
Stroke is a neurological emergency, where the mechanism of the blood supply to the brain is impaired, resulting in brain cell ischemia and death. Neuroinflammation is a key component in the ischemic cascade that results in cell damage and death after
Externí odkaz:
https://doaj.org/article/4bfcfef8bb3341b8bd56b61ecfa52562
Publikováno v:
International Journal of Molecular Sciences, Vol 16, Iss 11, Pp 26406-26416 (2015)
Recent studies suggested that sestrin2 is a crucial modulator for the production of reactive oxygen species (ROS). In addition, sestrin2 may also regulate ribosomal protein S6 (RpS6), a molecule important for protein synthesis, through the effect of
Externí odkaz:
https://doaj.org/article/e607c26a36934560bfad7c08ca22ceb1