Zobrazeno 1 - 10 of 15 pro vyhledávání: '"Shang-Chuan Ng"'
1
Akademický článek
Diallyl trisulfide (DATS) ameliorates cardiac fibrosis in a rat model of diabetes
Autor: Dennis Jine-Yuan Hsieh, Shang-Chuan Ng, Shang-Yeh Lu, Yen-Tun Chiu, Kuan-Ho Lin, Yueh-Min Lin, Chih-Yang Huang, Wei-Wen Kuo
Publikováno v: Journal of Functional Foods, Vol 111, Iss , Pp 105901- (2023)
Cardiac fibrosis is a prevalent pathological complication observed in individuals with diabetes. Diallyl trisulfide (DATS), a bioactive compound found in garlic oil, has been reported to exhibit anti-inflammatory and anti-apoptotic effects in various
Externí odkaz: https://doaj.org/article/ef4172a961aa40c1929b02fe526943eb
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2
Akademický článek
Activation of PI3K/Akt mediates the protective effect of diallyl trisulfide on doxorubicin induced cardiac apoptosis
Autor: Su-Ying Wen, Shang-Chuan Ng, Wen-Kun Ho, Han-Zhe Huang, Chih-Yang Huang, Wei-Wen Kuo
Publikováno v: Current Research in Toxicology, Vol 5, Iss , Pp 100136- (2023)
Diallyl trisulfide (DATS), an organosulfide compound derived from garlic, is renowned for its potent antioxidant properties, particularly in countering the generation of reactive oxygen species (ROS). It has also gained recognition as a potential age
Externí odkaz: https://doaj.org/article/42b4f8d1216345f780a062a4da6b0334
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4
Protective effects of galangin against H2O2/UVB-induced dermal fibroblast collagen degradation via hsa-microRNA-4535-mediated TGFβ/Smad signaling
Autor: Jian-Jr Lee, Shang-Chuan Ng, Yean-Tin Ni, Jian-Sheng Liu, Chih-Jung Chen, Viswanadha Vijaya Padma, Chih-Yang Huang, Wei-Wen Kuo
Publikováno v: Aging (Albany NY)
This study aimed to investigate the mechanism underlying the protective effects of galangin against H2O2/UVB-induced damage using in vitro and in vivo models of photodamage. Moreover, we identified the involvement of miRNA regulation in this process.
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::57aa3745b1c95c49da6f38ed46e37d97
https://doi.org/10.18632/aging.203750
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5
MicroRNA‐210 repression facilitates advanced glycation end‐product (AGE)‐induced cardiac mitochondrial dysfunction and apoptosis via JNK activation
Autor: Jian-Sheng Liu, Wei Wen Kuo, Hong-Chen Chen, Shang-Chuan Ng, Catherine R Paul, Kuan Ho Lin, Chih Yang Huang, Ren-You Zeng, V. Vijaya Padma
Publikováno v: Journal of Cellular Biochemistry. 122:1873-1885
Hyperglycemia results in the formation of reactive oxygen species which in turn causes advanced glycation end products (AGEs) formation, leading to diabetic cardiomyopathy. Our previous study showed that AGE-induced reactive oxygen species-dependent
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b9cfc7f6abc0a99dfaec3e959f82beaf
https://doi.org/10.1002/jcb.30146
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6
Seven traditional Chinese herbal extracts fermented by Lactobacillus rhamnosus provide anti‐pigmentation effects by regulating the CREB / MITF /tyrosinase pathway
Autor: Chih-Chu Ho, B Mahalakshmi, Jia-Yi Chen, Chia-Hua Kuo, Quoc-Vu Le, Chih Yang Huang, Su-Ying Wen, Wei Wen Kuo, Ho-Lin Chuang, Shang-Chuan Ng
Publikováno v: Environmental Toxicology. 36:654-664
Skin pigmentation is resulted from several processes, such as melanin synthesis transportation and abnormal melanin accumulation in keratinocytes. Various studies have suggested that seven traditional Chinese herbal extracts from Atractylodes macroce
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::ecc1b274f31fd07aa9d073516ebe11d7
https://doi.org/10.1002/tox.23069
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7
Extracts of Jasminum sambac flowers fermented by Lactobacillus rhamnosus inhibit H 2 O 2 ‐ and UVB‐induced aging in human dermal fibroblasts
Autor: Wei Wen Kuo, Shang-Chuan Ng, Chih-Chu Ho, Su-Ying Wen, Chih Yang Huang, Ho-Lin Chuang, B Mahalakshmi, Chia-Hua Kuo
Publikováno v: Environmental Toxicology. 36:607-619
Ultraviolet (UV) irradiation is a crucial factor that leads to skin photoaging and results in increased DNA damage, oxidative stress, and collagen degradation. Jasmine flowers have been utilized as a traditional medicine in Asia to treat various dise
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::c61441a70ffe568dc520898d08e4ac24
https://doi.org/10.1002/tox.23065
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8
Galangin Reverses H2O2-Induced Dermal Fibroblast Senescence via SIRT1-PGC-1α/Nrf2 Signaling
Autor: Jian-Jr Lee, Shang-Chuan Ng, Jia-Yun Hsu, Hsun Liu, Chih-Jung Chen, Chih-Yang Huang, Wei-Wen Kuo
Publikováno v: International Journal of Molecular Sciences; Volume 23; Issue 3; Pages: 1387
International Journal of Molecular Sciences, Vol 23, Iss 1387, p 1387 (2022)
UV radiation and H2O2 are the primary factors that cause skin aging. Both trigger oxidative stress and cellular aging. It has been reported that deacetylase silent information regulator 1 (SIRT1), a longevity gene, enhances activation of NF-E2-relate
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4297cee75f2bf0b19d820a0e26929dc4
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10
Akademický článek
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