Zobrazeno 1 - 10
of 98
pro vyhledávání: '"Shang Hung, Chen"'
Autor:
Chi-Che Hsieh, Ting-Wei Li, Chun-Chun Li, Shang-Hung Chen, You-Lin Wei, Nai-Jung Chiang, Che-Hung Shen
Publikováno v:
Oncogenesis, Vol 13, Iss 1, Pp 1-13 (2024)
Abstract Oxaliplatin is effective against colorectal cancer (CRC), but resistance hampers treatment. We found upregulated Dickkopf-1 (DKK1, a secreted protein) in oxaliplatin-resistant (OR) CRC cell lines and DKK1 levels increased by more than 2-fold
Externí odkaz:
https://doaj.org/article/ee2e1490b4cb44288d128c539eb734cf
Autor:
Siao Muk Cheng, Yung-Yeh Su, Nai-Jung Chiang, Chih-Jung Wang, Ying-Jui Chao, Chien-Jui Huang, Hui-Jen Tsai, Shang-Hung Chen, Chi-Yen Chang, Chia-Rung Tsai, Yi-Jie Li, Chia-Jui Yen, Shih-Chang Chuang, Jeffrey Shu-Ming Chang, Yan-Shen Shan, Daw-Yang Hwang, Li-Tzong Chen
Publikováno v:
Journal of Biomedical Science, Vol 31, Iss 1, Pp 1-14 (2024)
Abstract Background Cancer susceptibility germline mutations are associated with pancreatic ductal adenocarcinoma (PDAC). However, the hereditary status of PDAC and its impact on survival is largely unknown in the Asian population. Methods Exome sequ
Externí odkaz:
https://doaj.org/article/df7f60f9ec36445e8735f2495587c8d3
Autor:
Shang‐Hung Chen, Ka‐Po Tse, Yen‐Jung Lu, Shu‐Jen Chen, Yu‐Feng Tian, Kien Thiam Tan, Chien‐Feng Li
Publikováno v:
Cancer Medicine, Vol 13, Iss 12, Pp n/a-n/a (2024)
Abstract Background Breast cancer is a heterogeneous disease categorized based on molecular characteristics, including hormone receptor (HR) and human epidermal growth factor receptor 2 (HER2) expression levels. The emergence of profiling technology
Externí odkaz:
https://doaj.org/article/556eec84f6ec4018be34d1e7a502c792
Autor:
Sheng-Yen Hsiao, Shang-Mei Weng, Jenn-Ren Hsiao, Yi-Ying Wu, Jia-En Wu, Chia-Hao Tung, Wan-Lin Shen, Shu-Fang Sun, Wen-Tsung Huang, Cheng-Yao Lin, Shang-Hung Chen, Tse-Ming Hong, Yuh-Ling Chen, Jang-Yang Chang
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 42, Iss 1, Pp 1-19 (2023)
Abstract Background Lymph node and distant metastasis contribute to poor outcomes in patients with oral squamous cell carcinoma (OSCC). The mechanisms regulating cancer migration and invasion play a key role in OSCC. Methods We determined migration a
Externí odkaz:
https://doaj.org/article/0aac509a7647492fab204db355a88715
Autor:
Chia-Hung Chien, Wen-Bin Yang, Jian-Ying Chuang, Jung-Shun Lee, Wei-An Liao, Chih-Yuan Huang, Pin-Yuan Chen, An-Chih Wu, Shun-Tai Yang, Chien-Cheng Lai, Pei-I Chi, Jui-Mei Chu, Siao Muk Cheng, Chan-Chuan Liu, Daw-Yang Hwang, Shang-Hung Chen, Kwang-Yu Chang
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 41, Iss 1, Pp 1-14 (2022)
Abstract Background The mechanism by which glioblastoma evades temozolomide (TMZ)-induced cytotoxicity is largely unknown. We hypothesized that mitochondria plays a role in this process. Methods RNA transcriptomes were obtained from tumor samples and
Externí odkaz:
https://doaj.org/article/74d3093ae005449f902018ee36784041
Autor:
Shang-Hung Chen, Wen-Tsung Huang, Wan-Chen Kao, Sheng-Yen Hsiao, Hsin-Yi Pan, Chin-Wen Fang, Yow-Ling Shiue, Chia-Lin Chou, Chien-Feng Li
Publikováno v:
Journal of Biomedical Science, Vol 28, Iss 1, Pp 1-21 (2021)
Abstract Background The homologous recombination (HR) pathway is involved in DNA damage response (DDR), which is crucial to cancer cell survival after treatment with DNA damage agents. O6-methylguanine DNA methyltransferase (MGMT) is associated with
Externí odkaz:
https://doaj.org/article/336580ba0bb245cdb9a8dbf6b05b8023
Autor:
Yu-Min Yeh, Peng-Chan Lin, Chung-Ta Lee, Shang-Hung Chen, Bo-Wen Lin, Shao-Chieh Lin, Po-Chuan Chen, Ren-Hao Chan, Meng-Ru Shen
Publikováno v:
Molecular Cancer, Vol 19, Iss 1, Pp 1-6 (2020)
Abstract Circulating cell-free DNA (cfDNA) analysis is an important tool for cancer monitoring. The patient-specific mutations identified in colorectal cancer (CRC) tissues are usually used to design the cfDNA analysis. Despite high specificity in pr
Externí odkaz:
https://doaj.org/article/83ffba8e787d4cc38b9133bdef453344
Autor:
Chia-Hung Chien, Jian-Ying Chuang, Shun-Tai Yang, Wen-Bin Yang, Pin-Yuan Chen, Tsung-I Hsu, Chih-Yuan Huang, Wei-Lun Lo, Ka-Yen Yang, Ming-Sheng Liu, Jui-Mei Chu, Pei-Hsuan Chung, Jr-Jiun Liu, Shao-Wen Chou, Shang-Hung Chen, Kwang-Yu Chang
Publikováno v:
Journal of Biomedical Science, Vol 26, Iss 1, Pp 1-16 (2019)
Abstract Background Intratumor subsets with tumor-initiating features in glioblastoma are likely to survive treatment. Our goal is to identify the key factor in the process by which cells develop temozolomide (TMZ) resistance. Methods Resistant cell
Externí odkaz:
https://doaj.org/article/a4d420e0b4e94a6d81430e61fa42269e
Autor:
Shang-Hung Chen, Hsiang-Lin Tsai, Jeng-Kai Jiang, Yung-Chuan Sung, Ching-Wen Huang, Yu-Min Yeh, Li-Tzong Chen, Jaw-Yuan Wang
Publikováno v:
BMC Cancer, Vol 19, Iss 1, Pp 1-7 (2019)
Abstract Background In the management of patients with RAS wild-type metastatic colorectal cancer (mCRC), anti-epidermal growth factor receptor (EGFR) therapies have demonstrated a clinical benefit, with longer survival. However, the correlation betw
Externí odkaz:
https://doaj.org/article/8d64115be8ba444a9c430f4648739fb4
Autor:
Hsin-Yu Kuo, Meng-Zhi Han, Chih-Hsiang Liao, Yih-Jyh Lin, Chung-Teng Wang, Shang-Hung Chen, Ting-Tsung Chang, Po-Jun Chen, Sheng-Hsiang Lin, Chiung-Yu Chen, Chiao-Hsiung Chuang, I-Chin Wu, Juei-Seng Wu, Tzu-Chun Hong, Ming-Tsung Hsieh, Yang-Cheng Lee, Hung-Tsung Wu, Hong-Ming Tsai
Publikováno v:
Pharmaceutics, Vol 14, Iss 11, p 2263 (2022)
Purpose: Immune checkpoint inhibitors are effective therapies for advanced hepatocellular carcinoma (HCC); however, comparisons of the clinical efficacy and safety profile for these drugs are still scarce. Thus, the aims of this study were to investi
Externí odkaz:
https://doaj.org/article/ebb2164eecf94db09388c555197a1482