Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Shang‐Kun Dai"'
Autor:
Pei‐Pei Liu, Shang‐Kun Dai, Ting‐Wei Mi, Gang‐Bin Tang, Zhuo Wang, Hui Wang, Hong‐Zhen Du, Yi Tang, Zhao‐Qian Teng, Chang‐Mei Liu
Publikováno v:
EMBO Molecular Medicine, Vol 14, Iss 12, Pp 1-20 (2022)
Abstract Mutations in AT‐rich interactive domain‐containing protein 1A (ARID1A) cause Coffin‐Siris syndrome (CSS), a rare genetic disorder that results in mild to severe intellectual disabilities. However, the biological role of ARID1A in the b
Externí odkaz:
https://doaj.org/article/b4f7592562874eeaa694011fbfd342d4
Autor:
Pei-Pei Liu, Ya-Jie Xu, Shang-Kun Dai, Hong-Zhen Du, Ying-Ying Wang, Xing-Guo Li, Zhao-Qian Teng, Chang-Mei Liu
Publikováno v:
Stem Cell Reports, Vol 13, Iss 1, Pp 115-131 (2019)
Summary: EED (embryonic ectoderm development) is a core component of the Polycomb repressive complex 2 (PRC2) which catalyzes the methylation of histone H3 lysine 27 (H3K27) during the process of self-renewal, proliferation, and differentiation of em
Externí odkaz:
https://doaj.org/article/cf21ff90bee54e7eae1c52632ffbc2e3
Autor:
Xue-Qi Peng, Shang-Kun Dai, Chang-Ping Li, Pei-Pei Liu, Zhi-Meng Wang, Hong-Zhen Du, Zhao-Qian Teng, Shu-Guang Yang, Chang-Mei Liu
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 14 (2020)
Trauma or neurodegenerative diseases trigger the retrograde death of retinal ganglion cells (RGCs), causing an irreversible functional loss. AT-rich interaction domain 1A (ARID1A), a subunit of the SWItch/Sucrose Non-Fermentable (SWI/SNF) chromatin r
Externí odkaz:
https://doaj.org/article/239fde24534e44418fdf42e45f582e59
Autor:
Cong Liu, Shang-Kun Dai, Zhen Sun, Zhuo Wang, Pei-Pei Liu, Hong-Zhen Du, Shuyang Yu, Chang-Mei Liu, Zhao-Qian Teng
Publikováno v:
Stem Cell Research, Vol 39, Iss , Pp - (2019)
GA binding protein (GABP) is a ubiquitously expressed transcription factor that regulates the development of multiple cell types, including osteoblast, hematopoietic stem cells, B cells and T cells. However, so little is known about its biological fu
Externí odkaz:
https://doaj.org/article/fd800e8c912f443e90b05e71e0ee82ed
Autor:
Gang-Bin Tang, Yu-Qiang Zeng, Pei-Pei Liu, Ting-Wei Mi, Shuang-Feng Zhang, Shang-Kun Dai, Qing-Yuan Tang, Lin Yang, Ya-Jie Xu, Hai-Liang Yan, Hong-Zhen Du, Zhao-Qian Teng, Feng-Quan Zhou, Chang-Mei Liu
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 10 (2017)
Histone demethylase UTX mediates removal of repressive trimethylation of histone H3 lysine 27 (H3K27me3) to establish a mechanistic switch to activate large sets of genes. Mutation of Utx has recently been shown to be associated with Kabuki syndrome,
Externí odkaz:
https://doaj.org/article/037be87e5a04453da1ac2fe5de07e87e
Publikováno v:
Biochemical and Biophysical Research Communications. 613:187-192
Histone lysine crotonylation (Kcr) is a novel hydrophobic histone acylation modification, and we recently report its crucial roles in neural differentiation. However, it is still unclear how histone Kcr involve in early neural commitment. Here, we sy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::788eab6f60c5a4b00a06ba603ef00252
https://doi.org/10.1016/j.bbrc.2022.05.032
https://doi.org/10.1016/j.bbrc.2022.05.032
Autor:
Chang-Mei Liu, Pei-Pei Liu, Shi-Ping lu, Xiao Li, Gang-Bin Tang, Xiao Liu, Shang-Kun Dai, Lin-Fei Jiao, Xi-Wen Lin, Xing-Guo Li, Zhao-Qian Teng, Chunsheng Han
ARID1A, an SWI/SNF chromatin-remodeling gene, is commonly mutated in cancer and hypothesized to be a tumor suppressor. Recently, loss-of-function of ARID1A gene has been shown to cause intellectual disability. Here we generate Arid1a conditional knoc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a854c258b269cbe63ca7cdcdc0d3dc29
https://doi.org/10.21203/rs.3.rs-2735113/v1
https://doi.org/10.21203/rs.3.rs-2735113/v1
Autor:
Pei‐Pei Liu, Shang‐Kun Dai, Ting‐Wei Mi, Gang‐Bin Tang, Zhuo Wang, Hui Wang, Hong‐Zhen Du, Yi Tang, Zhao‐Qian Teng, Chang‐Mei Liu
Publikováno v:
EMBO Molecular Medicine. 14
Mutations in AT-rich interactive domain-containing protein 1A (ARID1A) cause Coffin-Siris syndrome (CSS), a rare genetic disorder that results in mild to severe intellectual disabilities. However, the biological role of ARID1A in the brain remains un
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::807cc78d40b672ab7678408bd558147d
https://doi.org/10.15252/emmm.202215795
https://doi.org/10.15252/emmm.202215795
Publikováno v:
Development. 149
Metabolites such as crotonyl-CoA and lactyl-CoA influence gene expression by covalently modifying histones, known as histone lysine crotonylation (Kcr) and lysine lactylation (Kla). However, the existence patterns, dynamic changes, biological functio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3196f6d3d1d1c558ae7802485071f36d
https://doi.org/10.1242/dev.200049
https://doi.org/10.1242/dev.200049
Autor:
Chang-Mei Liu, Ying-Ying Wang, Hong-Zhen Du, Zhao-Qian Teng, Qing Yuan Tang, Cong Liu, Shang-Kun Dai, Shuang-Feng Zhang
Publikováno v:
Stem Cell Reports
Summary UTX, a H3K27me3 demethylase, plays an important role in mouse brain development. However, so little is known about the function of UTX in human neural differentiation and dendritic morphology. In this study, we generated UTX-null human embryo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::42c9b66c7505bc42a868846e5b4a9b36
https://doi.org/10.1016/j.stemcr.2020.06.015
https://doi.org/10.1016/j.stemcr.2020.06.015