Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Shanell Mojta"'
Autor:
Karl J. M. Hanf, Joseph W. Arndt, YuTing Liu, Bang Jian Gong, Mia Rushe, Richelle Sopko, Ramiro Massol, Benjamin Smith, Yan Gao, Isin Dalkilic-Liddle, Xinhua Lee, Shanell Mojta, Zhaohui Shao, Sha Mi, R. Blake Pepinsky
Publikováno v:
mAbs, Vol 12, Iss 1 (2020)
LINGO-1 is a membrane protein of the central nervous system (CNS) that suppresses myelination of axons. Preclinical studies have revealed that blockade of LINGO-1 function leads to CNS repair in demyelinating animal models. The anti-LINGO-1 antibody
Externí odkaz:
https://doaj.org/article/90b48837c1134c3892cafeda6316ee68
Autor:
Shanell Mojta, Xinhua Lee, Yan Gao, Bang Jian Gong, Isin Dalkilic-Liddle, Ramiro H. Massol, YuTing Liu, Sha Mi, Karl J. M. Hanf, Benjamin Smith, Joseph Arndt, Zhaohui Shao, Richelle Sopko, R. Blake Pepinsky, Mia Rushe
Publikováno v:
mAbs
LINGO-1 is a membrane protein of the central nervous system (CNS) that suppresses myelination of axons. Preclinical studies have revealed that blockade of LINGO-1 function leads to CNS repair in demyelinating animal models. The anti-LINGO-1 antibody
Autor:
Crystal Cabral, Katherine Molloy, Joseph P. Nkolola, Alison L. Hill, David Jetton, Kathryn E. Stephenson, Maria G. Pau, Nelson L. Michael, Hanneke Schuitemaker, Peter Abbink, Lauren Peter, Jinyan Liu, Abishek Chandrashekar, Romas Geleziunas, Jeffrey M. Gerold, Galit Alter, Merlin L. Robb, Jessica Jimenez, Mark G. Lewis, Dan H. Barouch, Benjamin C. Lee, Jerome H. Kim, Joseph Hesselgesser, David Ng’ang’a, Erica N. Borducchi, Shanell Mojta, Amanda L. Brinkman, Jade Mondesir
Publikováno v:
Nature
The development of immunologic interventions that can target the viral reservoir in HIV-1-infected individuals is a major goal of HIV-1 research. However, little evidence exists that the viral reservoir can be sufficiently targeted to improve virolog
Autor:
Richard A. Koup, Amanda L. Brinkman, Dan H. Barouch, Brandon F. Keele, Boris Julg, Stephen D. Schmidt, Xuejun Chen, John R. Mascola, Jinyan Liu, Katherine Molloy, Shanell Mojta, Michael S. Seaman, Katherine Callow, Abishek Chandrashekar, Jinghe Huang, Peter Abbink, Keyun Wang, Amarendra Pegu, Mark Connors
Publikováno v:
Journal of Virology. 91
Passive immunotherapy against HIV-1 will most likely require broadly neutralizing antibodies (bnAbs) with maximum breadth and potency to ensure therapeutic efficacy. Recently, the novel CD4 binding site antibody N6 demonstrated extraordinary neutrali
Autor:
Richard G. Jarman, Kittipos Visitsunthorn, Michael R. Boyd, Ramya Nityanandam, Priya Gandhi, Shreeya Khatiwada, Ovini Nanayakkara, Marinela Kirilova, Nelson L. Michael, Kayvon Modjarrad, Rafael A. Larocca, Abishek Chandrashekar, Zhenfeng Li, Kenneth H. Eckels, Peter Abbink, Rafael De La Barrera, Mark G. Lewis, Stephen J. Thomas, David Jetton, Gregory D. Gromowski, Noe B. Mercado, Shanell Mojta, Erica N. Borducchi, Jake A. LeSuer, Dan H. Barouch, Rebecca Peterson
Publikováno v:
Science translational medicine. 9(420)
An effective Zika virus (ZIKV) vaccine will require long-term durable protection. Several ZIKV vaccine candidates have demonstrated protective efficacy in nonhuman primates, but these studies have typically involved ZIKV challenge shortly after vacci
Autor:
George H. Neubauer, Dan H. Barouch, Michael R. Boyd, Peter Abbink, Rafael De La Barrera, Mark G. Lewis, Jessica Jimenez, Richard G. Jarman, Christine A. Bricault, David Jetton, Noe B. Mercado, Edward T. Moseley, Jean Pierre Schatzmann Peron, Stephen J. Thomas, Nelson L. Michael, Arshi Agarwal, Crystal Cabral, Mayuri Shetty, Amanda L. Brinkman, Galit Alter, Brad Finneyfrock, Marinela Kirilova, Ramya Nityanandam, Shanell Mojta, Erica N. Borducchi, Kayvon Modjarrad, Rafael A. Larocca, Zhenfeng Li, Katherine Molloy, Benjamin C. Lee, Paolo Marinho de Andrade Zanotto, Abishek Chandrashekar, Patricia B. Giglio, Kathryn E. Stephenson, Ovini Nanayakkara, Johnathan Misamore, David Ng’ang’a, Kenneth H. Eckels
Publikováno v:
Science (New York, N.Y.). 353(6304)
Zika virus (ZIKV) is responsible for a major ongoing epidemic in the Americas and has been causally associated with fetal microcephaly. The development of a safe and effective ZIKV vaccine is therefore an urgent global health priority. Here we demons