Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Shanel Raghubeer"'
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-13 (2024)
Abstract Diabetes mellitus (DM) is characterized by impaired glucose and insulin metabolism, resulting in chronic hyperglycemia. Hyperglycemia-induced inflammation is linked to the onset and progression of diabetes. Resveratrol (RES), a polyphenol ph
Externí odkaz:
https://doaj.org/article/2869789dff8d43dd9672ea91a4a51d28
Autor:
Yvonne Prince, Glenda M. Davison, Saarah F.G. Davids, Rajiv T. Erasmus, Andre P. Kengne, Shanel Raghubeer, Tandi E. Matsha
Publikováno v:
Heliyon, Vol 10, Iss 10, Pp e31559- (2024)
Disturbances in the oral microbiota may be due to several mechanisms and factors, such as smoking. An imbalance in oral bacteria may result in changes to the innate immune system and the development of periodontal disease. This study aimed to investi
Externí odkaz:
https://doaj.org/article/7342323f3c8441fa89c6e15438ec2799
Autor:
Yvonne Prince, Glenda M. Davison, Saarah F. G. Davids, Rajiv T. Erasmus, Andre P. Kengne, Lisa M. Graham, Shanel Raghubeer, Tandi E. Matsha
Publikováno v:
Biomedicines, Vol 11, Iss 1, p 3 (2022)
The oral microbiota plays a crucial role in both systemic inflammation and metabolic syndrome (MetS), which is characterised by low-grade inflammation. Studies have analysed the gut microbiota using stool specimens from subjects with MetS; however, t
Externí odkaz:
https://doaj.org/article/815c53bf8b494b8ab8c9fd30a2b4b1aa
Autor:
Cecil J. Weale, Don M. Matshazi, Saarah F. G. Davids, Shanel Raghubeer, Rajiv T. Erasmus, Andre P. Kengne, Glenda M. Davison, Tandi E. Matsha
Publikováno v:
Frontiers in Genetics, Vol 12 (2021)
Aim: The influence of disease duration and anti-diabetic treatment on epigenetic processes has been described, with limited focus on interactions with microRNAs (miRNAs). miRNAs have been found to play key roles in the regulation of pathways associat
Externí odkaz:
https://doaj.org/article/9379b3e8f54f4bf597f7cfb184cd8158
Autor:
Don M. Matshazi, Cecil J. Weale, Rajiv T. Erasmus, Andre P. Kengne, Saarah F. G. Davids, Shanel Raghubeer, Glenda M. Davison, Tandi E. Matsha
Publikováno v:
Frontiers in Genetics, Vol 12 (2021)
MicroRNAs are non-coding, post-transcriptional regulators of gene expression and their dysregulation has been associated with development of various diseases, including hypertension. Consequently, understanding their role in the pathogenesis and prog
Externí odkaz:
https://doaj.org/article/2dfb007e921b4233948dca301a242b23
Autor:
Don M. Matshazi, Cecil J. Weale, Rajiv T. Erasmus, Andre P. Kengne, Saarah F. G. Davids, Shanel Raghubeer, Stanton Hector, Glenda M. Davison, Tandi E. Matsha
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 8 (2021)
Hypertension has a complex pathogenesis and symptoms appear in advanced disease. Dysregulation of gene expression regulatory factors like microRNAs has been reported in disease development. Identifying biomarkers which could help understand the patho
Externí odkaz:
https://doaj.org/article/f36ace27c13b41ac87f18b507fab83ac
Publikováno v:
Applied Sciences, Vol 11, Iss 20, p 9436 (2021)
Maturity-Onset Diabetes of the Young (MODY) is the most common form of monogenic diabetes resulting from a single gene mutation. It is characterized by mild hyperglycemia, autosomal dominant inheritance, early onset of diabetes (
Externí odkaz:
https://doaj.org/article/d7f76be2a64e49ec8786870d45d7d9e5
Autor:
Cecil J. Weale, Don M. Matshazi, Saarah F. G. Davids, Shanel Raghubeer, Rajiv T. Erasmus, Andre P. Kengne, Glenda M. Davison, Tandi E. Matsha
Publikováno v:
Diagnostics, Vol 11, Iss 6, p 949 (2021)
This cross-sectional study investigated the association of miR-1299, -126-3p and -30e-3p with and their diagnostic capability for dysglycaemia in 1273 (men, n = 345) South Africans, aged >20 years. Glycaemic status was assessed by oral glucose tolera
Externí odkaz:
https://doaj.org/article/0334ae5876444e069f74c91a88b55d81
Autor:
Wendy L. Solomon, Stanton B. E. Hector, Shanel Raghubeer, Rajiv T. Erasmus, Andre P. Kengne, Tandi E. Matsha
Publikováno v:
Epigenomes, Vol 4, Iss 3, p 19 (2020)
Metformin, which is used as a first line treatment for type 2 diabetes mellitus (T2DM), has been shown to affect epigenetic patterns. In this study, we investigated the DNA methylation and potential lncRNA modifications in metformin-treated and newly
Externí odkaz:
https://doaj.org/article/a8d7db81f8104bd786d016335df68dc6
Autor:
Shanel Raghubeer
Publikováno v:
Seminars in Cell & Developmental Biology.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::098ed9e496c5d2e15aedd57d067ebce0
https://doi.org/10.1016/j.semcdb.2023.02.006
https://doi.org/10.1016/j.semcdb.2023.02.006