Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Shane Walls"'
Autor:
Joshua A. Ballard, Timothy Kercher, David Abraham, Ryan Brecht, Nathan A. Brooks, Thomas Buckles, Desta Bume, David Busha, Ernst Peder Cedervall, Kevin Condroski, Kevin Ebata, Severine Isabelle Gharbi, Robert Hazlitt, Tony Morales, Nisha Patel, Jessica Podoll, Kaveri Urkalan, Sandra Gomez Villalain, Shane Walls, Faith Watson, Peiyi Yang, Barbara J. Brandhuber, Steven W. Andrews
Publikováno v:
Molecular Cancer Therapeutics. 20:P141-P141
Alterations in the fibroblast growth factor receptors (FGFRs) have been identified as oncogenic drivers in many human cancers. Specifically, activating FGFR3 gene alterations are found in ~15% of metastatic bladder cancers. One pan-FGFR inhibitor has
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::646b0e135391091fa9dfbd075ced65a3
https://doi.org/10.1158/1535-7163.targ-21-p141
https://doi.org/10.1158/1535-7163.targ-21-p141
Autor:
Shane Walls, Wei Wang, Yugen Zhu, Austin Jolly, Xiang Wang, Jessica D. Podoll, Lakota Cleaver
Publikováno v:
European Journal of Medicinal Chemistry. 125:130-142
Antibiotic-resistant bacterial infections have seen a marked increase in recent years, while antibiotic discovery has waned. Resistance-modifying agents (RMA) offer an intriguing alternative strategy to fight against resistant bacteria. Here we repor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::39a2c99ab7fc8c647b9eb90e36eb02e4
https://doi.org/10.1016/j.ejmech.2016.09.034
https://doi.org/10.1016/j.ejmech.2016.09.034
Publikováno v:
Journal of Medicinal Chemistry
Previously we discovered a tricyclic indoline, N-[2-(6-bromo-4-methylidene-2,3,4,4a,9,9a-hexahydro-1H-carbazol-4a-yl)ethyl]-4-chlorobenzene-1-sulfonamide (1, Of1), from bioinspired synthesis of a highly diverse polycyclic indoline alkaloid library, t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::51443f5f67d7f145e668054854ea9db2
https://pubmed.ncbi.nlm.nih.gov/24694192
https://pubmed.ncbi.nlm.nih.gov/24694192
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 110(39)
The continuous emergence of resistant bacteria has become a major worldwide health threat. The current development of new antibacterials has lagged far behind. To discover reagents to fight against resistant bacteria, we initiated a chemical approach
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d1ae627a4187d266d168a3d16cbcf535
https://pubmed.ncbi.nlm.nih.gov/24019472
https://pubmed.ncbi.nlm.nih.gov/24019472
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America; 9/24/2013, Vol. 110 Issue 39, p15573-15578, 6p
Autor:
Michaud, Thomas
Publikováno v:
Innovation, Between Science & Science Fiction; 2017, p1-66, 66p
Autor:
Thomas Michaud
Fantasy and science fiction are both involved in the process of innovation in techno-scientific societies. Long regarded as a hindrance to rationality, and to science, science fiction has become the object of praise in recent decades. Innovative orga
