Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Shane V. Formica"'
Autor:
Junyi Liang, Aditya Menon, Taylor Tomco, Nisha Bhattarai, Iris Nira Smith, Maria Khrestian, Shane V. Formica, Charis Eng, Matthias Buck, Lynn M. Bekris
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 17, p 9667 (2024)
Alzheimer’s disease is the most common form of dementia, characterized by the pathological accumulation of amyloid-beta (Aβ) plaques and tau neurofibrillary tangles. Triggering receptor expressed on myeloid cells 2 (TREM2) is increasingly recogniz
Externí odkaz:
https://doaj.org/article/5914e3ba6a4540d7a117040e2ecea11c
Autor:
Shane M. Bemiller, Nicole M. Maphis, Shane V. Formica, Gina N. Wilson, Crystal M. Miller, Guixiang Xu, Olga N. Kokiko-Cochran, Ki-Wook Kim, Steffen Jung, Judy L. Cannon, Samuel D. Crish, Astrid E. Cardona, Bruce T. Lamb, Kiran Bhaskar
Publikováno v:
Journal of Neuroinflammation, Vol 15, Iss 1, Pp 1-11 (2018)
Abstract Background Fractalkine (CX3CL1) and its receptor (CX3CR1) play an important role in regulating microglial function. We have previously shown that Cx 3 cr1 deficiency exacerbated tau pathology and led to cognitive impairment. However, it is s
Externí odkaz:
https://doaj.org/article/42a96fed8e3844aa981cac936e896290
Autor:
Shane M. Bemiller, Tyler J. McCray, Kevin Allan, Shane V. Formica, Guixiang Xu, Gina Wilson, Olga N. Kokiko-Cochran, Samuel D. Crish, Cristian A. Lasagna-Reeves, Richard M. Ransohoff, Gary E. Landreth, Bruce T. Lamb
Publikováno v:
Molecular Neurodegeneration, Vol 12, Iss 1, Pp 1-12 (2017)
Abstract Background Genetic variants of the Triggering Receptor Expressed on Myeloid Cells-2 (TREM2) confer increased risk of developing late-onset Alzheimer’s Disease (LOAD) and other neurodegenerative disorders. Recent studies provided insight in
Externí odkaz:
https://doaj.org/article/d537fc31545b4db78783ea737d60c189