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Autor:
Jeng Yie Chan, Thomas W.H. Kay, Katsuya Dezaki, Kim Loh, James Cantley, Esteban Nicolas Gurzov, Stacey N. Walters, Kailun Lee, Chi Kin Ip, Shane St Grey, Ross Laybutt, Toshihiko Yada, Herbert Herzog, Yan-Chuan Shi, Helen E. Thomas, Michaela Waibel, Masanori Nakata, Mohammed Bensellam
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-12 (2017)
Nature Communications
Nature communications, 8 (1
Nature Communications
Nature communications, 8 (1
Failure to secrete sufficient quantities of insulin is a pathological feature of type-1 and type-2 diabetes, and also reduces the success of islet cell transplantation. Here we demonstrate that Y1 receptor signaling inhibits insulin release in β-cel