Zobrazeno 1 - 10
of 112
pro vyhledávání: '"Shane R, Thomas"'
Publikováno v:
Antioxidants, Vol 13, Iss 7, p 788 (2024)
Coronary artery disease (CAD) and myocardial infarction (MI) remain leading causes of death and disability worldwide. CAD begins with the formation of atherosclerotic plaques within the intimal layer of the coronary arteries, a process driven by pers
Externí odkaz:
https://doaj.org/article/0f81422dbd9148138d9a6cf5b33e08ad
Autor:
Patrick T. San Gabriel, Thomas R. O’Neil, Alice Au, Jian K. Tan, Gabriela V. Pinget, Yuyang Liu, Genevieve Fong, Jacqueline Ku, Elias Glaros, Laurence Macia, Paul K. Witting, Shane R. Thomas, Belal Chami
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 8, p 4258 (2024)
Neutrophil-myeloperoxidase (MPO) is a heme-containing peroxidase which produces excess amounts of hypochlorous acid during inflammation. While pharmacological MPO inhibition mitigates all indices of experimental colitis, no studies have corroborated
Externí odkaz:
https://doaj.org/article/f31e89a4fabc4ba4a937df683ac62071
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 12, Iss 4 (2023)
Excessive inflammation and impaired healing of cardiac tissue following a myocardial infarction (MI) can drive the development of heart failure. Cardiac repair begins immediately after the onset of MI and continues for months. The repair process can
Externí odkaz:
https://doaj.org/article/c8d050a11f154a329b0e223e6f0d8978
Autor:
Maria Parvaneh, Paul K. Witting, Jaqueline Ku, Tala Moradi, Elif Eroglu, Ben Freedman, Greg T. Sutherland, Andrew McCorkindale, Boris Guennewig, Phannaphat Choowong, Kim Bell-Anderson, Gregory Cooney, Shane R. Thomas, Joerg Eberhard
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-10 (2021)
Abstract The treatment of periodontitis has numerous positive effects on established chronic health conditions, including cardiovascular disease and diabetes. However, ethical considerations do limit the establishment of human trials to investigate w
Externí odkaz:
https://doaj.org/article/3290d562eb7d40e5b7d7eca71b22cb2f
Autor:
Tien K. Nguyen, Stephanie Paone, Enoch Chan, Ivan K. H. Poon, Amy A. Baxter, Shane R. Thomas, Mark D. Hulett
Publikováno v:
Cells, Vol 11, Iss 20, p 3198 (2022)
Cardiovascular disease (CVD) is the leading cause of death and disability worldwide, and its management places a huge burden on healthcare systems through hospitalisation and treatment. Atherosclerosis is a chronic inflammatory disease of the arteria
Externí odkaz:
https://doaj.org/article/46bfd90df202454d8a17f3786326abb2
Autor:
Siân P. Cartland, Hanis H. Harith, Scott W. Genner, Lei Dang, Victoria C. Cogger, Melissa Vellozzi, Belinda A. Di Bartolo, Shane R. Thomas, Leon A. Adams, Mary M. Kavurma
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-12 (2017)
Abstract Non-alcoholic fatty liver disease (NAFLD) incorporates steatosis, non-alcoholic steato-hepatitis (NASH) and liver cirrhosis, associating with diabetes and cardiovascular disease (CVD). TNF-related apoptosis-inducing ligand (TRAIL) is protect
Externí odkaz:
https://doaj.org/article/08febdc07f6d49f998e77ef88d225185
Autor:
Bikash Manandhar, Elvis Pandzic, Nandan Deshpande, Sing-Young Chen, Valerie Wasinger, Maaike Kockx, Elias Glaros, Kwok Leung Ong, Shane R. Thomas, Marc R. Wilkins, Renee M. Whan, Blake J. Cochran, Kerry-Anne Rye
Objective:High cholesterol levels in pancreatic β-cells cause oxidative stress and decrease insulin secretion. β-cells can internalize apolipoprotein (apo) A-I, which increases insulin secretion. This study asks whether internalization of apoA-I im
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::71940cb463272863273b924c9e868188
https://doi.org/10.1101/2023.04.03.535492
https://doi.org/10.1101/2023.04.03.535492
Autor:
Chris K. Hewson, Alexander Capraro, Sharon L. Wong, Elvis Pandzic, Ling Zhong, Bentotage S. M. Fernando, Nikhil T. Awatade, Gene Hart-Smith, Renee M. Whan, Shane R. Thomas, Adam Jaffe, Wallace J. Bridge, Shafagh A. Waters
Publikováno v:
Antioxidants, Vol 9, Iss 12, p 1204 (2020)
Systemic glutathione deficiency, inflammation, and oxidative stress are hallmarks of cystic fibrosis (CF), an inherited disease that causes persistent lung infections and severe damage to the respiratory system and many of the body organs. Improvemen
Externí odkaz:
https://doaj.org/article/ded626cf578c43c38dbe8569a71c6601
Autor:
Rabab Nasrallah, Kathy Knezevic, Thuan Thai, Shane R. Thomas, Berthold Göttgens, Georges Lacaud, Valerie Kouskoff, John E. Pimanda
Publikováno v:
Biology Open, Vol 4, Iss 7, Pp 819-829 (2015)
During embryonic development, hematopoietic cells develop by a process of endothelial-to hematopoietic transition of a specialized population of endothelial cells. These hemogenic endothelium (HE) cells in turn develop from a primitive population of
Externí odkaz:
https://doaj.org/article/7170c9b962c04c36a9031f2807d3dc38
Publikováno v:
Best Practice & Research Clinical Endocrinology & Metabolism. 37:101689
The high density lipoprotein (HDL) fraction of human plasma consists of multiple subpopulations of spherical particles that are structurally uniform, but heterogeneous in terms of size, composition and function. Numerous epidemiological studies have
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::99c5fbeadff7939904c6a2e6985cf8d7
https://doi.org/10.1016/j.beem.2022.101689
https://doi.org/10.1016/j.beem.2022.101689