Zobrazeno 1 - 10
of 51
pro vyhledávání: '"Shane Plunkett"'
Autor:
Mateusz Rytelewski, Karine Haryutyunan, Felix Nwajei, Meenakshi Shanmugasundaram, Patrick Wspanialy, M. Anna Zal, Chao-Hsien Chen, Mirna El Khatib, Shane Plunkett, Sergei A. Vinogradov, Marina Konopleva, Tomasz Zal
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 7, Iss 1, Pp 1-13 (2019)
Abstract Background Low availability of oxygen in tumors contributes to the hostility of the tumor microenvironment toward the immune system. However, the dynamic relationship between local oxygen levels and the immune surveillance of tumors by tumor
Externí odkaz:
https://doaj.org/article/4bf32cd720d5400e8da29de1f33ac7bd
Autor:
Mateusz Rytelewski, Karine Harutyunyan, Natalia Baran, Saradhi Mallampati, M. Anna Zal, Antonio Cavazos, Jason M. Butler, Sergej Konoplev, Mirna El Khatib, Shane Plunkett, Joseph R. Marszalek, Michael Andreeff, Tomasz Zal, Marina Konopleva
Publikováno v:
Frontiers in Oncology, Vol 10 (2020)
Abnormally low level of interstitial oxygen, or hypoxia, is a hallmark of tumor microenvironment and a known promoter of cancer chemoresistance. Inside a solid tumor mass, the hypoxia stems largely from inadequate supply of oxygenated blood through s
Externí odkaz:
https://doaj.org/article/04b6ea0b0f514755b3a0d14df43854f4
Publikováno v:
Org Lett
Methyl groups can imbue valuable properties in organic molecules, often leading to enhanced bioactivity. To enable efficient installation of methyl groups on simple building blocks and in late-stage functionalization, a nickel-catalyzed reductive cou
Autor:
Mathias O. Senge, Pınar Arpaçay, Alina Meindl, Ahmed M. El-Zohry, Shane Plunkett, Omar F. Mohammed, Werner J. Blau, Partha Maity, Sevilay Akca
Publikováno v:
The Journal of Physical Chemistry C. 123:14283-14291
Push–pull porphyrins are made of an electron donor (D), an electron acceptor (A), and a conjugated bridge connecting the D and A units. The tunability of their highest occupied molecular orbital (H...
Publikováno v:
Journal of the American Chemical Society. 141:2257-2262
A Negishi cross-coupling of alkyl pyridinium salts and alkylzinc halides has been developed. This is the first example of alkyl–alkyl bond formation via cross-coupling of an alkyl amine derivative with an unactivated alkyl group, and allows both pr
Publikováno v:
Organic letters. 22(19)
A convergent method for the rapid preparation of substituted isocoumarins is reported. The transformation takes advantage of a spontaneous intramolecular cyclization that follows the Pd-catalyzed α-arylation of aldehydes with 2-halobenzoic esters. T
Autor:
Joshua E. Collins, Anand Kumar, Shane Plunkett, Sergei A. Vinogradov, Jason E Porter, Ikbal Sencan, Sava Sakadžić, Mirna El Khatib
Publikováno v:
Nanoscale
Lanthanide-based upconverting nanoparticles (UCNPs) are known for their remarkable ability to convert near-infrared energy into higher energy light, offering an attractive platform for construction of biological imaging probes. Here we focus on in vi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::426cf3d2f2a80dce8903d1f38696f257
https://europepmc.org/articles/PMC7101076/
https://europepmc.org/articles/PMC7101076/
Autor:
Mathias O. Senge, Keith J. Flanagan, Aoife A. Ryan, Alina Meindl, Susan Callaghan, Shane Plunkett
Publikováno v:
European Journal of Organic Chemistry. 2017:3565-3583
Contemporary applications in optics, medicine, solar cells, or material science are increasingly reliant on unsymmetrically substituted porphyrins. Due to their widespread applications and rise in demand we undertook a comparative analysis of synthet
Publikováno v:
Org Lett
An alkyl-alkyl cross-coupling of Katritzky alkylpyridinium salts and organoboranes, formed in situ via hydroboration of alkenes, has been developed. This method utilizes the abundance of both alkyl amine precursors and alkenes to form C(sp3)-C(sp3) b
Autor:
Shane Plunkett, Edward B. Brown, Xinping Zhang, Sergei A. Vinogradov, Jiajia Xue, Younan Xia, Mirna El Khatib, Kevin Schilling
Publikováno v:
ACS applied materialsinterfaces. 11(37)
Tissue oxygenation is one of the key determining factors in bone repair and bone tissue engineering. Adequate tissue oxygenation is essential for survival and differentiation of the bone-forming cells and ultimately the success of bone tissue regener