Výsledky vyhledávání - "Shane O. LeBeau"

Benign call rate and molecular test result distribution of ThyroSeq v3

Autor: Pooja Manroa, N. Paul Ohori, Shane O. LeBeau, Marina N. Nikiforova, Yuri E. Nikiforov, Raja R. Seethala, Michael S. Landau, Sally E. Carty, Karen E. Schoedel, Linwah Yip

Publikováno v: Cancer Cytopathology. 127:161-168

Background The benign call rate (BCR) is the percentage of cytomorphologically indeterminate cases with subsequent benign or negative molecular results. For rule-out tests, the BCR is an important parameter because these molecular "negative" cases ma

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a82a28517335faf59b07d9d0c7b8d241
https://doi.org/10.1002/cncy.22088

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Comparison of the collection approaches of 2 large thyroid fine-needle aspiration practices reveals differing advantages for cytology and molecular testing adequacy rates

Autor: Thomas M. Pearce, Sally E. Carty, Jenna Wolfe, Kelly L. McCoy, Michael S. Landau, Mitchell Tublin, Shane O. LeBeau, Linwah Yip, N. Paul Ohori

Publikováno v: Journal of the American Society of Cytopathology. 8(5)

At our institution, almost all thyroid fine-needle aspiration (FNA) procedures are performed by either Endocrinology or Radiology personnel. In this study, we compared the cytology and molecular adequacy rates of these 2 thyroid FNA practices, which

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::27dc302281de92fe48145e05c6cbe673
https://pubmed.ncbi.nlm.nih.gov/31543223

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Significance of what is not sampled: Characteristics of thyroid nonmicrocarcinomas (>1.0 cm) that were not targeted

Autor: Sally E. Carty, Steven P. Hodak, Jenna Wolfe, Karen E. Schoedel, Marina N. Nikiforova, Yuri E. Nikiforov, Shane O. LeBeau, Linwah Yip, N. Paul Ohori

Publikováno v: Cancer Cytopathology. 123:678-683

BACKGROUND Although most unsuspected thyroid carcinomas qualify as microcarcinomas (≤1 cm), larger, nontargeted carcinomas may be found also. This study evaluated the significance of these nonmicrocarcinomas (>1 cm) in the setting of a large-volume

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::895e996e8d7e7a46681ffc623edc50b8
https://doi.org/10.1002/cncy.21603

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The influence of the noninvasive follicular thyroid neoplasm with papillary-like nuclear features (NIFTP) resection diagnosis on the false-positive thyroid cytology rate relates to quality assurance thresholds and the application of NIFTP criteria

Autor: Linwah Yip, Sally E. Carty, Karen E. Schoedel, Shane O. LeBeau, Jenna Wolfe, N. Paul Ohori, Raja R. Seethala, Aaron N. Berg, Yuri E. Nikiforov

Publikováno v: Cancer cytopathology. 125(9)

BACKGROUND Noninvasive follicular thyroid neoplasm with papillary-like nuclear features (NIFTP) is a newly defined entity and recent studies have suggested a decrease of a few percentage points in the rate of malignancy (ROM) for the positive-for-mal

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::27b96c3dd8dab81bf19d417056ef032e
https://pubmed.ncbi.nlm.nih.gov/28678437

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Correct extent of thyroidectomy is poorly predicted preoperatively by the guidelines of the American Thyroid Association for low and intermediate risk thyroid cancers

Autor: Sally E. Carty, Kelly L. McCoy, Mashaal Dhir, Cameron D. Adkisson, Linwah Yip, Shane O. LeBeau, N. Paul Ohori

Publikováno v: Surgery. 163(1)

Recent guidelines from the American Thyroid Association recommend thyroid lobectomy for intrathyroidal differentiated thyroid cancers4 cm. Our aim was to examine histology from patients with cytologic results that were positive or suspicious for mali

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::576b0a69fff72924528f0a540f404ce8
https://pubmed.ncbi.nlm.nih.gov/29128175

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Highly accurate diagnosis of cancer in thyroid nodules with follicular neoplasm/suspicious for a follicular neoplasm cytology by ThyroSeq v2 next-generation sequencing assay

Autor: Christopher J. Coyne, Sally E. Carty, Simon I. Chiosea, Raja R. Seethala, N. Paul Ohori, Robert L. Ferris, Mitchell Tublin, Steven P. Hodak, Umamaheswar Duvvuri, William E. Gooding, Linwah Yip, Yuri E. Nikiforov, Marina N. Nikiforova, Shane O. LeBeau

Publikováno v: Cancer. 120:3627-3634

Background Fine-needle aspiration (FNA) cytology is a common approach to evaluating thyroid nodules, although 20% to 30% of FNAs have indeterminate cytology, which hampers the appropriate management of these patients. Follicular (or oncocytic) neopla

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::02936e46290903b9c9e655799796aabe
https://doi.org/10.1002/cncr.29038

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Thyroid nodules withKRASmutations are different from nodules withNRASandHRASmutations with regard to cytopathologic and histopathologic outcome characteristics

Autor: Shane O. LeBeau, Steven P. Hodak, Kelly L. McCoy, Linwah Yip, Karen E. Schoedel, Yuri E. Nikiforov, Raja R. Seethala, N. Paul Ohori, Marina N. Nikiforova, Lisa A. Radkay, Simion I. Chiosea, Sally E. Carty

Publikováno v: Cancer Cytopathology. 122:873-882

BACKGROUND Mutations in the RAS gene in the thyroid gland result in the activation of signaling pathways and are associated with a follicular growth pattern and the probability of a carcinoma outcome ranging from 74% to 87%. In the current study, the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::0b3ae8ac9fe376bc3050710d5ccea18d
https://doi.org/10.1002/cncy.21474

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Thyroid Nodules (≥4 cm): Can Ultrasound and Cytology Reliably Exclude Cancer?

Autor: Biatta Sholosh, Kelly L. McCoy, Sally E. Carty, Linwah Yip, N. Paul Ohori, Laura I. Wharry, Mitch E. Tublin, Steven P. Hodak, Yuri E. Nikiforov, Michaele J. Armstrong, Michael T. Stang, Ari Silbermann, Shane O. LeBeau

Publikováno v: World Journal of Surgery. 38:614-621

Whether a threshold nodule size should prompt diagnostic thyroidectomy remains controversial. We examined a consecutive series of patients who all had thyroidectomy for a ≥4 cm nodule to determine (1) the incidence of thyroid cancer (TC) and (2) if

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e3c0750a60d03457534768e71fb7eec7
https://doi.org/10.1007/s00268-013-2261-9

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Nodule size is an independent predictor of malignancy in mutation-negative nodules with follicular lesion of undetermined significance cytology

Autor: Jonas T. Johnson, Christopher Coyne, Mitchell Tublin, Linwah Yip, Kelly L. McCoy, Marina N. Nikiforova, Rohtesh S. Mehta, Steven P. Hodak, N. Paul Ohori, Yuri E. Nikiforov, Shane O. LeBeau, Sally E. Carty, Michael T. Stang

Publikováno v: Surgery. 154:730-738

Background In thyroid nodule fine-needle aspiration (FNA) cytology, the atypia of undetermined significance or follicular lesion of undetermined significance (AUS/FLUS) category has a 5–15% malignancy risk that increases to 85–99% when mutation t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a90cd6965fa91c1145e77b854d8548f
https://doi.org/10.1016/j.surg.2013.05.015

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