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pro vyhledávání: '"Shane Mackey"'
Autor:
Alexander Sands, Allison L. Bayer, Jennifer Rodriguez, Cecilia Cabello-Kindelan, Alberto Pugliese, Shane Mackey, Claudia Vazquez
Publikováno v:
Diabetes. 69:215-227
Optimal immune-based therapies for type 1 diabetes (T1D) should restore self-tolerance without inducing chronic immunosuppression. CD4+Foxp3+ regulatory T cells (Tregs) are a key cell population capable of facilitating durable immune tolerance. Howev
Autor:
Cecilia, Cabello-Kindelan, Shane, Mackey, Alexander, Sands, Jennifer, Rodriguez, Claudia, Vazquez, Alberto, Pugliese, Allison L, Bayer
Publikováno v:
Diabetes
Optimal immune-based therapies for type 1 diabetes (T1D) should restore self-tolerance without inducing chronic immunosuppression. CD4(+)Foxp3(+) regulatory T cells (T(regs)) are a key cell population capable of facilitating durable immune tolerance.
Publikováno v:
Current Transplantation Reports. 2:191-201
There is a clear need to develop strategies to induce tolerance without the need of chronic immunosuppression in transplant recipient and in patients with autoimmunity. Adoptive T regulatory cell (Treg) therapy offers the potential of long-lasting pr