Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Shane M Ceraul"'
Autor:
Rebecca S Pelc, Jennifer C McClure, Simran J Kaur, Khandra T Sears, M Sayeedur Rahman, Shane M Ceraul
Publikováno v:
PLoS ONE, Vol 10, Iss 3, p e0119283 (2015)
Peptide Nucleic Acids (PNAs) are single-stranded synthetic nucleic acids with a pseudopeptide backbone in lieu of the phosphodiester linked sugar and phosphate found in traditional oligos. PNA designed complementary to the bacterial Shine-Dalgarno or
Externí odkaz:
https://doaj.org/article/9f533af26cf149b4a6368b4e50f6d12b
Autor:
M Sayeedur Rahman, Joseph J Gillespie, Simran Jeet Kaur, Khandra T Sears, Shane M Ceraul, Magda Beier-Sexton, Abdu F Azad
Publikováno v:
PLoS Pathogens, Vol 9, Iss 6, p e1003399 (2013)
The long-standing proposal that phospholipase A2 (PLA2) enzymes are involved in rickettsial infection of host cells has been given support by the recent characterization of a patatin phospholipase (Pat2) with PLA2 activity from the pathogens Ricketts
Externí odkaz:
https://doaj.org/article/a9dec9b022fd4010afd1f888fee6c68a
Autor:
Khandra T Sears, Shane M Ceraul, Joseph J Gillespie, Edwin D Allen, Vsevolod L Popov, Nicole C Ammerman, M Sayeedur Rahman, Abdu F Azad
Publikováno v:
PLoS Pathogens, Vol 8, Iss 8, p e1002856 (2012)
Surface proteins of the obligate intracellular bacterium Rickettsia typhi, the agent of murine or endemic typhus fever, comprise an important interface for host-pathogen interactions including adherence, invasion and survival in the host cytoplasm. I
Externí odkaz:
https://doaj.org/article/84c3396a75874741b90fc8e06fe95039
Autor:
Joseph J Gillespie, Kelly Williams, Maulik Shukla, Eric E Snyder, Eric K Nordberg, Shane M Ceraul, Chitti Dharmanolla, Daphne Rainey, Jeetendra Soneja, Joshua M Shallom, Nataraj Dongre Vishnubhat, Rebecca Wattam, Anjan Purkayastha, Michael Czar, Oswald Crasta, Joao C Setubal, Abdu F Azad, Bruno S Sobral
Publikováno v:
PLoS ONE, Vol 3, Iss 4, p e2018 (2008)
Completed genome sequences are rapidly increasing for Rickettsia, obligate intracellular alpha-proteobacteria responsible for various human diseases, including epidemic typhus and Rocky Mountain spotted fever. In light of phylogeny, the establishment
Externí odkaz:
https://doaj.org/article/ca2718f17ef5494d84359b74b0b8300d
Publikováno v:
Insect Molecular Biology
The importance of tick defensins is evidenced by their expression in a wide variety of tick tissues and prevalence across many tick genera. To date, the functional and biological significance of defensin-2 as a rickettsiastatic or rickettsiacidal ant
Autor:
Vsevolod L. Popov, Khandra T. Sears, Shane M. Ceraul, Magda Beier-Sexton, Abdu F. Azad, M. Sayeedur Rahman, Ashley Chung
Publikováno v:
Infection and Immunity. 79:321-329
A defining facet of tick- Rickettsia symbioses is the molecular strategy employed by each partner to ensure its own survival. Ticks must control rickettsial colonization to avoid immediate death. In the current study, we show that rickettsial abundan
Publikováno v:
Journal of Bacteriology. 192:3294-3303
Phospholipase A 2 (PLA 2 ) has long been proposed to be involved in rickettsial entry into host cells, escape from the phagosome to evade destruction by lysosomal exposure, and lysis of the host cells. However, the corresponding rickettsial gene(s) e
Autor:
Joseph J. Gillespie, J. M. Anderson, R. C. Jochim, S. C. Lesnick, Shane M. Ceraul, Sheila M. Dreher-Lesnick, Jesus G. Valenzuela, Abdu F. Azad
Publikováno v:
Insect Molecular Biology. 19:229-241
Murine typhus is a flea-borne febrile illness that is caused by the obligate intracellular bacterium, Rickettsia typhi. The cat flea, Ctenocephalides felis, acquires R. typhi by imbibing a bloodmeal from a rickettsemic vertebrate host. To explore whi
Publikováno v:
Journal of Medical Entomology. 45:68-74
Publikováno v:
Experimental and Applied Acarology. 36:207-223
Antimicrobial midgut proteins and peptides that result from blood digestion in feeding American dog ticks Dermacentor variabilis (Say) were identified. Midgut extracts from these ticks showed antimicrobial activity against Micrococcus luteus, regardl