Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Shane Houston"'
Autor:
Bas Brouwers, Edson Mendes de Oliveira, Maria Marti-Solano, Fabiola B.F. Monteiro, Suli-Anne Laurin, Julia M. Keogh, Elana Henning, Rebecca Bounds, Carole A. Daly, Shane Houston, Vikram Ayinampudi, Natalia Wasiluk, David Clarke, Bianca Plouffe, Michel Bouvier, M. Madan Babu, I. Sadaf Farooqi, Jacek Mokrosiński
Publikováno v:
Cell Reports, Vol 34, Iss 12, Pp 108862- (2021)
Summary: The Melanocortin-4 Receptor (MC4R) plays a pivotal role in energy homeostasis. We used human MC4R mutations associated with an increased or decreased risk of obesity to dissect mechanisms that regulate MC4R function. Most obesity-associated
Externí odkaz:
https://doaj.org/article/47adf08d015c4c769ac1331dc6211c1b
Autor:
Gavin Mooney, Shane Houston
Publikováno v:
Cadernos de Saúde Pública, Vol 24, Iss 5, Pp 1162-1167 (2008)
Communitarianism acknowledges and values, and not just instrumentally, the bonds that unite and identify communities. Communitarians also value community per se. This paper argues that trust is likely to be stronger in communities where these bonds a
Externí odkaz:
https://doaj.org/article/e92d8d6b0b8a4e24bd05ff8c866d4590
Autor:
Bianca Plouffe, Angeliki Karamitri, Tilman Flock, Jonathan M. Gallion, Shane Houston, Carole A. Daly, Amélie Bonnefond, Jean-Luc Guillaume, Christian Le Gouill, Phillipe Froguel, Olivier Lichtarge, Xavier Deupi, Ralf Jockers, Michel Bouvier
Publikováno v:
Plouffe, B, Karamitri, A, Flock, T, Gallion, J M, Houston, S, Daly, C A, Bonnefond, A, Guillaume, J-L, Le Gouill, C, Froguel, P, Lichtarge, O, Deupi, X, Jockers, R & Bouvier, M 2022, ' Structural elements directing G proteins and β-arrestin interactions with the human melatonin type 2 receptor revealed by natural variants ', ACS Pharmacology & Translational Science, vol. 5, no. 2, pp. 89-101 . https://doi.org/10.1021/acsptsci.1c00239
G protein-coupled receptors (GPCRs) can engage distinct subsets of signaling pathways, but the structural determinants of this functional selectivity remain elusive. The naturally occurring genetic variants of GPCRs, selectively affecting different p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a10e88db95d723db444f3c797d249364
https://doi.org/10.1021/acsptsci.1c00239
https://doi.org/10.1021/acsptsci.1c00239
Autor:
M. Madan Babu, Elana Henning, Maria Marti-Solano, Bianca Plouffe, Carole A. Daly, Julia M. Keogh, Michel Bouvier, Bas Brouwers, Rebecca Bounds, Jacek Mokrosinski, Fabiola B.F. Monteiro, I. Sadaf Farooqi, Suli-Anne Laurin, Vikram Ayinampudi, David Clarke, Natalia Wasiluk, Edson Mendes de Oliveira, Shane Houston
Publikováno v:
Cell Reports
Brouwers, B, Mendes de Oliveira, E, Marti-Solano, M, B.F. Monteiro, F, Laurin, S-A, M. Keogh, J, Henning, E, Bounds, R, Daly, C A, Houston, S, Ayinampudi, V, Wasiluk, N, Clarke, D, Plouffe, B, Bouvier, M, Babu, M M, Farooqi, I S & Mokrosinski, J 2021, ' Human MC4R variants affect endocytosis, trafficking and dimerization revealing multiple cellular mechanisms involved in weight regulation ', Cell Reports, vol. 34, no. 12, 108862 . https://doi.org/10.1016/j.celrep.2021.108862
Cell Reports, Vol 34, Iss 12, Pp 108862-(2021)
Brouwers, B, Mendes de Oliveira, E, Marti-Solano, M, B.F. Monteiro, F, Laurin, S-A, M. Keogh, J, Henning, E, Bounds, R, Daly, C A, Houston, S, Ayinampudi, V, Wasiluk, N, Clarke, D, Plouffe, B, Bouvier, M, Babu, M M, Farooqi, I S & Mokrosinski, J 2021, ' Human MC4R variants affect endocytosis, trafficking and dimerization revealing multiple cellular mechanisms involved in weight regulation ', Cell Reports, vol. 34, no. 12, 108862 . https://doi.org/10.1016/j.celrep.2021.108862
Cell Reports, Vol 34, Iss 12, Pp 108862-(2021)
Summary The Melanocortin-4 Receptor (MC4R) plays a pivotal role in energy homeostasis. We used human MC4R mutations associated with an increased or decreased risk of obesity to dissect mechanisms that regulate MC4R function. Most obesity-associated m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3bfbe7d13739699591dbf337515cfb5d
Autor:
Shane Houston
Publikováno v:
The Medical journal of Australia. 205(1)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d40c7d5758e6829f079795eb6d09cb04
https://pubmed.ncbi.nlm.nih.gov/27362680
https://pubmed.ncbi.nlm.nih.gov/27362680
Autor:
Ian Anderson, Stephen Jan, Michael E. Otim, Edward Shane Houston, Margaret Kelaher, Ranmalie Jayasinha
Publikováno v:
International Indigenous Policy Journal, Vol 6, Iss 3 (2015)
Indigenous Australians have significantly poorer health outcomes than the non-Indigenous population worldwide. The Australian government has increased its investment in Indigenous health through the "Closing the Health Gap" initiative. Deciding where
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9457902c58e00611a8cd23d176012150
http://ir.lib.uwo.ca/iipj/vol6/iss3/8/
http://ir.lib.uwo.ca/iipj/vol6/iss3/8/
Autor:
Shane Houston
Publikováno v:
Health Promotion Journal of Australia. 17:206-210
Equity has in many instances been framed around the notion of fairness. But the metric used to determine what is fair leaves some people at a disadvantage because the things that they value are not always taken properly into account. If I value mango
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d2e4e9df9a9ad23859a44070bde1176b
https://doi.org/10.1071/he06206
https://doi.org/10.1071/he06206
Publikováno v:
Medical Journal of Australia. 180:517-520
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0f49a1337560025ae99122ef9852ad21
https://doi.org/10.5694/j.1326-5377.2004.tb06056.x
https://doi.org/10.5694/j.1326-5377.2004.tb06056.x
Autor:
Rinaldo, Bellomo, Satoshi, Suzuki, Bruno, Marino, Graeme K, Starkey, Brenton, Chambers, Michael A, Fink, Bao Zhong, Wang, Shane, Houston, Glenn, Eastwood, Paolo, Calzavacca, Neil, Glassford, Alison, Skene, Daryl A, Jones, Robert, Jones
Publikováno v:
Critical care and resuscitation : journal of the Australasian Academy of Critical Care Medicine. 14(3)
Liver transplantation is a major life-saving procedure, and donation after cardiac death (DCD) has increased the pool of potential liver donors. However, DCD livers are at increased risk of primary graft dysfunction and biliary tract ischaemia. Normo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::c31dcec1f857f896399dd682cc029a53
https://pubmed.ncbi.nlm.nih.gov/22963210
https://pubmed.ncbi.nlm.nih.gov/22963210
Autor:
Gavin Mooney, Shane Houston
Publikováno v:
Applied health economics and health policy. 3(1)
This article outlines an approach to resource allocation in healthcare that embraces the concepts of ‘capacity to benefit’ and management economic social and human (MESH) infrastructure. Health service jurisdictions differ in terms of their capac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c89711af72d5af69ae2d386018ef7939
https://pubmed.ncbi.nlm.nih.gov/15702937
https://pubmed.ncbi.nlm.nih.gov/15702937