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pro vyhledávání: '"Shane Glasgow"'
Palmitic acid is a toll-like receptor 4 ligand that induces human dendritic cell secretion of IL-1β.
Autor:
Dequina A Nicholas, Kangling Zhang, Christopher Hung, Shane Glasgow, Aruni Wilson Aruni, Juli Unternaehrer, Kimberly J Payne, William H R Langridge, Marino De Leon
Publikováno v:
PLoS ONE, Vol 12, Iss 5, p e0176793 (2017)
Palmitic acid (PA) and other saturated fatty acids are known to stimulate pro-inflammatory responses in human immune cells via Toll-like receptor 4 (TLR4). However, the molecular mechanism responsible for fatty acid stimulation of TLR4 remains unknow
Externí odkaz:
https://doaj.org/article/f4f7cabda7da4fb6ac03a7ce1cbd7027
Autor:
Aruni Wilson Aruni, Kangling Zhang, Christopher Hung, Shane Glasgow, Juli Unternaehrer, William H. R. Langridge, Marino De Leon, Kimberly J. Payne, Dequina A. Nicholas
Publikováno v:
PLoS ONE, Vol 12, Iss 5, p e0176793 (2017)
PLoS ONE
PLoS ONE
Palmitic acid (PA) and other saturated fatty acids are known to stimulate pro-inflammatory responses in human immune cells via Toll-like receptor 4 (TLR4). However, the molecular mechanism responsible for fatty acid stimulation of TLR4 remains unknow
Autor:
Lawrence D. Longo, Shane Glasgow, Sean M. Wilson, Donald M. Bers, Noah Osman, Leighton T. Izu, Xiaoxiao Tao, Jose L. Puglisi, Monica Romero, David A. Hessinger
Publikováno v:
The FASEB Journal. 28
Ryanodine receptor (RyR) activity causes Ca2+ sparks in cerebral arterial myocytes by activating adjacent Ca2+-activated K+ (BK) channels, which can dilate arteries. Previous studies show ontogeny increases Ca2+ sparks and long-term hypoxia (LTH) inc
Autor:
Gema Suarez, Jose L. Puglisi, Leighton T. Izu, Sean M. Wilson, Shane Glasgow, Lawerence Longo, Noah Osman, Donald M. Bers, Monica Romero
Publikováno v:
The FASEB Journal. 28
Antenatal chronic hypoxia can lead to pulmonary hypertension in newborns or more severe vascular remodeling and dangerous elevations in pressure. We have previously shown that antenatal chronic hypoxia deregulates Ca2+ spark activity, which are impor
Autor:
Sean M. Wilson, Ricardo Paez, Michael Francis, Shane Glasgow, Monica Romero, Quintin Blood, Lawerence Longo, Noah Osman, Mark S. Taylor, Chetas Manjunath
Publikováno v:
The FASEB Journal. 28
High altitude is a risk factor in the development of pulmonary hypertension (PH). Treatment often includes the use of phosphodiesterase (PDE) inhibitors of PDE3 (milrinone, cAMP) and PDE5 (sildenaf...