Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Shane Formica"'
Publikováno v:
Mol Immunol
Alzheimer's disease (AD) is characterized by the accumulation in the brain of extracellular amyloid β (Aβ) plaques as well as intraneuronal inclusions (neurofibrillary tangles) consisting of total tau and phosphorylated tau. Also present are dystro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1db1ef4906ba134f8824b7c3b11434e6
https://europepmc.org/articles/PMC8147571/
https://europepmc.org/articles/PMC8147571/
Alzheimer’s disease (AD) is characterized by the accumulation in the brain of extracellular amyloid β (Aβ) plaques as well as intraneuronal inclusions (neurofibrillary tangles) consisting of total tau and phosphorylated tau. Also present are dyst
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d9c891d3cbc14da529e18fed858ca3c2
https://doi.org/10.1101/2020.10.08.329938
https://doi.org/10.1101/2020.10.08.329938
Autor:
Lynn M. Bekris, James B. Leverenz, Rumana Akhter, Shane Formica, McKenzie Shaw, Maria Khrestian, Yvonne Shao
Publikováno v:
Neurobiology of Aging. 63:110-119
Recent reports in Alzheimer's disease (AD) research suggest that alterations in microRNA (miRNA) expression are associated with disease pathology. Our previous studies suggest that A Disintegrin and Metalloproteinase 10 (ADAM10) expression is importa
Autor:
Richard M. Ransohoff, Samuel D. Crish, Guixiang Xu, Shane M. Bemiller, Gary E. Landreth, Olga N. Kokiko-Cochran, Shane Formica, Tyler J. McCray, Kevin C. Allan, Cristian A. Lasagna-Reeves, Gina N. Wilson, Bruce T. Lamb
Publikováno v:
Molecular Neurodegeneration, Vol 12, Iss 1, Pp 1-12 (2017)
Molecular Neurodegeneration
Molecular Neurodegeneration
Background Genetic variants of the Triggering Receptor Expressed on Myeloid Cells-2 (TREM2) confer increased risk of developing late-onset Alzheimer’s Disease (LOAD) and other neurodegenerative disorders. Recent studies provided insight into the mu
Autor:
Maria Khrestian, Shane Formica, Thomas J. Montine, Lynn M. Bekris, Yvonne Shao, James B. Leverenz, McKenzie Shaw, Jeffrey A. Zahratka, Kaitlin Todd
Publikováno v:
Neurobiology of Aging. 51:43-53
Neurofibrillary tangles (NFTs), composed of hyperphosphorylated tau, are a key pathologic feature of Alzheimer's disease (AD). Tau phosphorylation is under the control of multiple kinases and phosphatases, including Fyn. Previously, our group found a
Autor:
Ki-Wook Kim, Steffen Jung, Samuel D. Crish, Judy L. Cannon, Nicole Maphis, Guixiang Xu, Astrid E. Cardona, Kiran Bhaskar, Shane Formica, Bruce T. Lamb, Olga N. Kokiko-Cochran, Gina N. Wilson, Crystal M. Miller, Shane M. Bemiller
Publikováno v:
Journal of Neuroinflammation, Vol 15, Iss 1, Pp 1-11 (2018)
Background Fractalkine (CX3CL1) and its receptor (CX3CR1) play an important role in regulating microglial function. We have previously shown that Cx 3 cr1 deficiency exacerbated tau pathology and led to cognitive impairment. However, it is still uncl
Autor:
Yvonne Shao, Rumana Akhter, Lynn M. Bekris, Maria Khrestian, James B. Leverenz, Shane Formica, McKenzie Shaw
Publikováno v:
Alzheimer's & Dementia. 13