Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Shane E. Holloway"'
Autor:
Rolf A. Brekken, Jason B. Fleming, Carlton C. Barnett, Adam W. Beck, David S. Shames, James P. Sullivan, Andrew F. Miller, Shane E. Holloway, Kristi D. Lynn, Sean P. Dineen
Macrophages are an abundant inflammatory cell type in the tumor microenvironment that can contribute to tumor growth and metastasis. Macrophage recruitment into tumors is mediated by multiple cytokines, including vascular endothelial growth factor (V
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f45ef1dcba6a7d75b06ca7fd89fa5e97
https://doi.org/10.1158/0008-5472.c.6497619
https://doi.org/10.1158/0008-5472.c.6497619
Autor:
Rolf A. Brekken, Jason B. Fleming, Carlton C. Barnett, Adam W. Beck, David S. Shames, James P. Sullivan, Andrew F. Miller, Shane E. Holloway, Kristi D. Lynn, Sean P. Dineen
Supplementary Figure 1 from Vascular Endothelial Growth Factor Receptor 2 Mediates Macrophage Infiltration into Orthotopic Pancreatic Tumors in Mice
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ff2279db85e6902270362bfc1318dcb
https://doi.org/10.1158/0008-5472.22374867.v1
https://doi.org/10.1158/0008-5472.22374867.v1
Autor:
Rolf A. Brekken, Jason B. Fleming, Carlton C. Barnett, Adam W. Beck, David S. Shames, James P. Sullivan, Andrew F. Miller, Shane E. Holloway, Kristi D. Lynn, Sean P. Dineen
Supplementary Figure 2 from Vascular Endothelial Growth Factor Receptor 2 Mediates Macrophage Infiltration into Orthotopic Pancreatic Tumors in Mice
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a9bd11671179becb40bde5f48a5cd0e
https://doi.org/10.1158/0008-5472.22374864.v1
https://doi.org/10.1158/0008-5472.22374864.v1
Publikováno v:
Journal of the American College of Surgeons. 207:731-736
Background We sought to evaluate the feasibility and outcomes of laparoscopic resection of symptomatic hepatic cysts. Study Design Fifty-one patients underwent laparoscopic resections for symptomatic hepatic cysts. Resection was accomplished laparosc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a374f6d09972d41a4041f6e8b4b8eea7
https://doi.org/10.1016/j.jamcollsurg.2008.07.009
https://doi.org/10.1016/j.jamcollsurg.2008.07.009
Autor:
Shane E. Holloway, Latha Shivakumar, Adam W. Beck, Jessica Shih, Jason B. Fleming, Rolf A. Brekken
Publikováno v:
Annals of Surgical Oncology. 13:1145-1155
Vascular endothelial growth factor (VEGF), a key regulator of angiogenesis, is critical for growth of human pancreatic adenocarcinoma. Preclinical studies demonstrate that blockade of VEGF activity can control the growth of pancreatic tumors in mice.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2df553ae5fd51e644dc66b10271ad883
https://doi.org/10.1245/aso.2006.05.049
https://doi.org/10.1245/aso.2006.05.049
Autor:
Adam W. Beck, Christopher R. Conner, Shane E. Holloway, Troy A. Luster, Carlton C. Barnett, Philip E. Thorpe, Jason B. Fleming, Andrew F. Miller, Rolf A. Brekken
Publikováno v:
International Journal of Cancer. 118:2639-2643
Pancreatic cancer continues to have a dismal prognosis and novel therapy is needed. In this study, we evaluate a promising new target for therapy, phosphatidylserine (PS). PS is an anionic phospholipid located normally on the inner leaflet of the pla
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1fbe18553f5ee0db2eb05cd5bcfe3993
https://doi.org/10.1002/ijc.21684
https://doi.org/10.1002/ijc.21684
Autor:
John S, Hammond, Jan, Franko, Shane E, Holloway, Jason T, Heckman, Phillip D, Orons, T Clark, Gamblin
Publikováno v:
Hepato-gastroenterology. 61(133)
Transcatheter arterial chemoembolization (TACE) has been shown to increase survival in patients with unresectable hepatocellular carcinoma (HCC), however toxicity from commonly used agents limits its use in unresectable disease. Gemcitabine is a well
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::bd7b45fc5415766cafc3fa11e3a3759a
https://pubmed.ncbi.nlm.nih.gov/25436307
https://pubmed.ncbi.nlm.nih.gov/25436307
Publikováno v:
Molecular Cancer Research. 3:413-423
Mutation of the K-ras gene is an early event in the development of pancreatic adenocarcinoma and, therefore, RNA interference (RNAi) directed toward mutant K-ras could represent a novel therapy. In this study, we examine the phenotypic and molecular
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::122bc80ef8a3db961e2bce0a3a7632a3
https://doi.org/10.1158/1541-7786.mcr-04-0206
https://doi.org/10.1158/1541-7786.mcr-04-0206
Autor:
Shane E. Holloway, M. Raffat Jaber, Luc Girard, Carlton C. Barnett, Adam W. Beck, Rolf A. Brekken, Jason B. Fleming
Publikováno v:
Journal of the American College of Surgeons. 200:371-377
Background Identification of extracellular matrix proteins (ECM) associated with tumor cell metastasis may generate targets for future therapy against pancreatic cancer metastases. We hypothesized that comparison of ECM-associated gene expression in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ede8dc7d7a70e5109e0343d0439e0025
https://doi.org/10.1016/j.jamcollsurg.2004.10.005
https://doi.org/10.1016/j.jamcollsurg.2004.10.005
Publikováno v:
International Journal of Gastrointestinal Cancer. 33:61-70
Genetic alterations impacting the TGF-β/Smad4 pathway are found in nearly all pancreatic adenocarcinomas, and recent reports have identified a relationship between DPC4/Smad4 expression and patient survival. In this study we use a clinically relevan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b7fc641c1fffc1d9ce45b147d6d54afa
https://doi.org/10.1385/ijgc:33:1:61
https://doi.org/10.1385/ijgc:33:1:61