Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Shane A. Saywell"'
Publikováno v:
The Journal of Physiology. 588:4431-4439
Since protein kinase-dependent modulation of motoneuronal excitability contributes to adaptive changes in breathing, we hypothesized that cGMP-dependent pathways activating protein kinase G (PKG) modulate motoneuronal inspiratory drive currents and l
Publikováno v:
The Journal of Neuroscience. 27:4435-4442
In vitrolong-term facilitation (ivLTF) is a novel form of activity-independent postsynaptic enhancement of AMPA receptor function in hypoglossal (XII) motoneurons that can be induced by intermittent activation of 5-HT2receptors.In vivorespiratory lon
Publikováno v:
The Journal of Physiology. 579:765-782
The descending control of respiratory-related motoneurones in the thoracic spinal cord remains the subject of some debate. In this study, direct connections from expiratory bulbospinal neurones to identified motoneurones were investigated using spike
Publikováno v:
Respiratory Physiology & Neurobiology. 147:131-143
Motoneuronal excitability is highly modulated by various inputs; however, comparatively little is known about postsynaptic signal transduction cascades that affect motoneuron excitability. In this review, we discuss the role of intracellular signalin
Autor:
Jack L. Feldman, Shane A. Saywell
Publikováno v:
The Journal of Physiology. 554:879-889
The balance of excitation and inhibition converging upon a neurone is a principal determinant of neuronal output. We investigated the role of inhibition in shaping and gating inspiratory drive to hypoglossal (XII) motoneuronal activity. In neonatal r
Autor:
Revers Donga, C. F. Meehan, Tim W. Ford, Natalia P. Anissimova, Peter A. Kirkwood, Jeremy Road, Shane A. Saywell
Publikováno v:
The Journal of Comparative Neurology. 472:281-291
Retrograde transport of horseradish peroxidase, applied to cut peripheral nerves, was used to determine the rostrocaudal distribution of motoneurones supplying different branches of the ventral ramus for a single mid- or caudal thoracic segment in th
Publikováno v:
Physiological Reports
Renshaw cells are widely distributed in all segments of the spinal cord, but detailed morphological studies of these cells and their axonal branching patterns have only been made for lumbosacral segments. For these, a characteristic distribution of t
Propriospinal interneurons in the thoracic spinal cord have vital roles not only in controlling respiratory and trunk muscles, but also in providing possible substrates for recovery from spinal cord injury. Intracellular recordings were made from suc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b05cf69ef268eded208fb57bf6e0a9ea
https://europepmc.org/articles/PMC3059177/
https://europepmc.org/articles/PMC3059177/
Publikováno v:
The Journal of physiology. 588(Pt 22)
Since protein kinase-dependent modulation of motoneuronal excitability contributes to adaptive changes in breathing, we hypothesized that cGMP-dependent pathways activating protein kinase G (PKG) modulate motoneuronal inspiratory drive currents and l
Publikováno v:
The Journal of neuroscience : the official journal of the Society for Neuroscience. 23(4)
Plasticity underlying adaptive, long-term changes in breathing behavior is hypothesized to be attributable to the modulation of respiratory motoneurons by intracellular second-messenger cascades. In quiescent preparations, protein kinases, including