Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Shane, English"'
Autor:
Brittany Dennis, Adam Deane, François Lauzier, Nicole Zytaruk, Miranda Hardie, Naomi Hammond, Simon Finfer, Yaseen Arabi, John Marshall, Lois Saunders, Diane Heels-Ansdell, John Myburgh, Serena Knowles, John Muscedere, Marlies Ostermann, Dorrilyn Rajbhandari, Shane English, Karlo Matic, Bala Venkatesh, Abdulrahman Al Fares, Gordon Guyatt, Waleed Alhazzani, Hassan Mumtaz, Alexis Poole, Feng Xie, Lehana Thabane, Richard Hall, Deborah Cook
Publikováno v:
BMC Medical Research Methodology, Vol 24, Iss 1, Pp 1-10 (2024)
Abstract Background During the COVID-19 pandemic, many intensive care units (ICUs) halted research to focus on COVID-19-specific studies. Objective To describe the conduct of an international randomized trial of stress ulcer prophylaxis (Re-Evaluatin
Externí odkaz:
https://doaj.org/article/bd70c4426fae4e6585d45506d3cf8e59
Autor:
Greg Knoll, Bram Rochwerg, François Lauzier, Marat Slessarev, Michaël Chasse, Karen E A Burns, Alexis F Turgeon, John Gordon Boyd, Frédérick D'Aragon, Shane English, Matthew Weiss, Maureen Meade, Sonny Dhanani, Marie-Hélène Masse, François-Martin Carrier, Steven Hanna, Andrew Healey, Simon J W Oczkowski, Anne-Julie Frenette, Anique Ducharme, Prosanto Chaudhury, Markus Selzner, Ruth Breau, Mélanie Masse, Héloïse Cardinal, Brigitte Bolduc, Caroline Lamarche, Etienne Couture, Sandra Holdsworth, Liz Bertholz, Heather Talbot, Patrick Luke, M Khaled Shamseddin, Jeffrey Zaltzman, Darin Treleaven
Publikováno v:
BMJ Open, Vol 14, Iss 6 (2024)
Introduction Most solid organ transplants originate from donors meeting criteria for death by neurological criteria (DNC). Within the organ donor, physiological responses to brain death increase the risk of ischaemia reperfusion injury and delayed gr
Externí odkaz:
https://doaj.org/article/0da023b6c5d4443aad540ffec3e61c6c
Autor:
Diane Heels-Ansdell, Laurent Billot, Lehana Thabane, Waleed Alhazzani, Adam Deane, Gordon Guyatt, Simon Finfer, François Lauzier, John Myburgh, Paul Young, Yaseen Arabi, John Marshall, Shane English, John Muscedere, Marlies Ostermann, Bala Venkatesh, Nicole Zytaruk, Miranda Hardie, Naomi Hammond, Serena Knowles, Lois Saunders, Alexis Poole, Abdulrahman Al-Fares, Feng Xie, Richard Hall, Deborah Cook
Publikováno v:
Trials, Vol 24, Iss 1, Pp 1-9 (2023)
Abstract Background The REVISE (Re-Evaluating the Inhibition of Stress Erosions in the ICU) trial will evaluate the impact of the proton pump inhibitor pantoprazole compared to placebo in invasively ventilated critically ill patients. Objective To ou
Externí odkaz:
https://doaj.org/article/f43b3946a0134c0d91e8980efc07406e
Autor:
Brittany B. Dennis, Lehana Thabane, Diane Heels-Ansdell, Joanna C. Dionne, Alexandra Binnie, Jennifer Tsang, Gordon Guyatt, Aijaz Ahmed, François Lauzier, Adam Deane, Yaseen Arabi, John Marshall, Nicole Zytaruk, Lois Saunders, Simon Finfer, John Myburgh, John Muscedere, Shane English, Marlies Ostermann, Miranda Hardie, Serena Knowles, Deborah Cook, For the REVISE Investigators the Canadian Critical Care Trials Group
Publikováno v:
Trials, Vol 24, Iss 1, Pp 1-10 (2023)
Abstract Background Critically ill patients commonly receive proton pump inhibitors (PPIs) to prevent gastrointestinal (GI) bleeding from stress-induced ulceration. Despite widespread use in the intensive care unit (ICU), observational data suggest t
Externí odkaz:
https://doaj.org/article/bdfab15867474f8e8cd4f0e5dcbdda5e
Autor:
Lehana Thabane, Gordon Guyatt, Diane Heels-Ansdell, Deborah J Cook, Yaseen Arabi, John Muscedere, Paul Young, Feng Xie, François Lauzier, Laurent Billot, Waleed Alhazzani, Marlies Ostermann, Shane English, Daniel Johnson, John C Marshall, Nicole Zytaruk, Balasubramanian Venkatesh, Simon Finfer, John Myburgh, R Hall, Mobeen Iqbal, Abdulrahman A Al-Fares, Gilmar Reis, Alexis Poole, Adam M Deane, Marianne J Chapman, Dorrilyn Rajbhandari, Naomi E Hammond, Serena Knowles, Miranda Hardie, Lois Saunders
Publikováno v:
BMJ Open, Vol 13, Iss 11 (2023)
Introduction The Re-Evaluating the Inhibition of Stress Erosions (REVISE) Trial aims to determine the impact of the proton pump inhibitor pantoprazole compared with placebo on clinically important upper gastrointestinal (GI) bleeding in the intensive
Externí odkaz:
https://doaj.org/article/6494babd732e4acaa7d4de624fcce7da
Autor:
Julia F Shaw, Yongdong Ouyang, Dean A Fergusson, Tracy McArdle, Claudio Martin, Deborah Cook, Ian D Graham, Steven Hawken, Colin J L McCartney, Kusum Menon, Raphael Saginur, Andrew Seely, Ian Stiell, Alison Fox-Robichaud, Shane English, John Marshall, Kednapa Thavorn, Monica Taljaard, Lauralyn A McIntyre
Publikováno v:
JMIR Research Protocols, Vol 12, p e51783 (2023)
BackgroundNormal saline (NS) and Ringer’s lactate (RL) are the most common crystalloids given to hospitalized patients. Despite concern about possible harm associated with NS (eg, hyperchloremic metabolic acidosis, impaired kidney function, and dea
Externí odkaz:
https://doaj.org/article/8521863c0cd044cbb66fb0f5dfed7cd3
Autor:
Charles Weijer, Loretta Norton, Teneille Gofton, Marat Slessarev, Michaël Chasse, John Gordon Boyd, Frédérick D'Aragon, Shane English, Maureen Meade, Sam Shemie, Sonny Dhanani, Andreas H Kramer, Jennifer Chandler, Eileen Campbell, Jeffrey Singh, Yun-Hee Choi, Maxwell J Smith, Erika Chamberlain, Nathan B Scales, Nicholas Murphy, Derek Debicki, Tadeu A Fantaneanu, Julie Kromm, Tracey C Bentall
Publikováno v:
BMJ Open, Vol 13, Iss 4 (2023)
Introduction In donation after circulatory determination of death, death is declared 5 min after circulatory arrest. This practice assumes, but does not explicitly confirm, permanent loss of brain activity. While this assumption is rooted a strong ph
Externí odkaz:
https://doaj.org/article/a52f80cfa80a47258d986aeed2940013
Autor:
Robert S Green, Dean A Fergusson, Demetrios J Kutsogiannis, Ryan Zarychanski, Kosar Khwaja, Donald Griesdale, François Lauzier, Alison Fox-Robichaud, Ian Ball, Alexis F Turgeon, John Gordon Boyd, Paul C Hébert, Shane English, Timothy Walsh, Andreas H Kramer, John C Marshall, Damon Scales, Olivier Costerousse, Annemarie Docherty, Andrea Rigamonti, Maude St-Onge, Lucy Clayton, Marie-Pier Patton, Karen E. A. Burns, Paule Lessard Bonaventure, Xavier Neveu, Vincent Laroche
Publikováno v:
BMJ Open, Vol 12, Iss 10 (2022)
Introduction Traumatic brain injury (TBI) is the leading cause of mortality and long-term disability in young adults. Despite the high prevalence of anaemia and red blood cell transfusion in patients with TBI, the optimal haemoglobin (Hb) transfusion
Externí odkaz:
https://doaj.org/article/08d78388f188440695220058ef5266a2
Autor:
Luciana Souza-Moreira, Yuan Tan, Yan Wang, Jia-Pey Wang, Mahmoud Salkhordeh, Jennifer Virgo, Maria Florian, Aidan B.P. Murray, Irene Watpool, Lauralyn McIntyre, Shane English, Duncan J. Stewart, Shirley H.J. Mei
Publikováno v:
iScience, Vol 25, Iss 5, Pp 104188- (2022)
Summary: Mesenchymal stem cells (MSCs) are being studied for the treatment of COVID-19-associated critical illness, due to their immunomodulatory properties. Here, we hypothesized that viral mimic-priming improves MSCs’ abilities to rebalance the d
Externí odkaz:
https://doaj.org/article/219bbd6189184d6dae0755e8c2f65c0d
Autor:
Dean A Fergusson, Alan J Forster, Alan Tinmouth, Kednapa Thavorn, Steven Hawken, Kumanan Wilson, Michaël Chasse, Shane English, Nadine Shehata, Jason P Acker, Angie Tuttle, Iris Perelman, Nancy Cober, Heather Maddison, Melanie Tokessy
Publikováno v:
BMJ Open, Vol 11, Iss 2 (2021)
Introduction With over 1 million units of blood transfused each year in Canada, their use has a significant clinical and economic impact on our health system. Adequate screening of blood donors is important to ensure the safety and clinical benefit o
Externí odkaz:
https://doaj.org/article/f7205ca7f0cb4b5d8ab8e1161e95293a